This was the experience of @douglasmich
The same happened a me to Konflict with Vitamin E-K2.
Better shut up, indian.
Anti-estrogen vitamins are dangerous to us.
Vitamin D is anti-estrogenic where it’s needed
According to an animal and cell study that endocrinologists at Stanford University published in Endocrinology, the active form of vitamin D – calcitriol [structural formula shown below] – is an anti-oestrogenic compound. The study is interesting for bodybuilders too, as the anti-estrogenic effect of vitamin D is expressed mostly in the fat tissue. What’s more, vitamin D enhances the effect of anti-oestrogens like anastrozole, letrozole and exemestane.
Study
The researchers want to know whether dietary changes can reduce the chance of breast cancer in women and improve treatment chances in women who already have breast cancer. Estradiol causes most breast cancer cell types to grow faster. So doctors treat breast cancer with drugs that reduce the concentration of estradiol. The researchers already knew that vitamin D blocks the production of the alpha-estradiol receptor in cells, and wondered whether vitamin D also reduces the production of estradiol itself. That would happen by inhibiting the enzyme aromatase, which converts androstenedione and testosterone into estradiol.
To answer this question the researchers did trials with female mice that had had human cancer cell implants. The mice were given 0.1 mg androstenedione daily, and for the three days before the researchers analyzed them they were given a daily injection of 0.75 mg calcitriol as well. [Cal] A control group was given injections containing inactive ingredients. [Veh]
Results
The figure below shows that the cancer cells and the fat cells of the Cal mice produced less aromatase.
The figure to the right shows that in human cells estradiol production declines as the concentration of calcitriol increases. This effect is interesting for chemical bodybuilders.
Less estradiol means that fat cells can’t grow so easily and so shrink faster. It also means less risk of gyno. At least, if it’s valid to extrapolate the results of this study to humans.
The researchers also studied the joint effect on the growth of cancer cells of aromatase inhibitors when taken with arimidex, exemestane and letrozole on the one hand and with vitamin D on the other. The researchers grew human cancer cells in test tubes and added testosterone together with aromatase inhibitors and vitamin D. The figure below shows that vitamin D enhances the effect of arimidex, and the figures for exemestane and letrozole were pretty similar.
Conclusions
The researchers used 0.1 and 1.0 nanomol concentrations of calcitriol. Concentrations of calcitriol in humans vary between 0.05 and 0.16 nmol. Because westerners in general have too little vitamin D in their blood, many chemical bodybuilders will derive more effect from the aromatase inhibitors they take by adding a supplement that contains extra vitamin D.
Racism? I do not see anything.
Do I blame you if you are Indian? lol
And THIS what’s that instead?
Better shut up, you too.
Still dangerous advice.
I would ban you too.
Why would u mention the fact he is an Indian, Italian?
I can ask the same question to you.
I did it because u did it to him, why did you do it?
Do you get offended if I tell you you’re Hollander?
It is useless for you to defend him, I am right.
But, why, did u do it? What was the purpose? The relevance.
Racismmm hahahaha
Feel men, no purpose, no longer talk to me.
I do not tolerate dangerous advice.
U used his nationality in an insulting sentence. U said, shut up, Indian. Zero need to mention his nationallity, u just want to insult him. U can ofcourse say no no, i just said his nationallity, what’s bad about that. But we all know better, and u will probably not take responsibility for this either.
Comment on this.
Ciao Holland Boy.
For me it closes here.
Wake up!
You have to worry for the health of patients
instead of idiot and national bullshit.
This is enough. I will close this thread and will contact people individually once I have more time. Neither insults nor irresponsible advice is welcomed here.