Crashed Vitamin d3

one of supplements i was taking at moment where i started having crashes again was vitamin d3 so its possible it can affect negativily some of us

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My situation was very serious but still stable but unfortunately I made a mistake, to try Vitamin d3 (Dibase Cholecalciferol 50.000Ui) a single dose and I got seriously worse. Since I had a total loss of muscle-bones, I decided to try the vitamin in question. Within half an hour of taking it I had a worsening of all neurological, physical and sexual symptoms. After 4 days I wake up one morning with new symptoms I list:

Total anesthesia to the body
Tingling of the limbs
Very dry skin
Pale, dehydrated skin
Very dry hair
Penis disappeared
Darker penis skin
Light / soft bones
Hypermobility of the joints (Look Video)
Light bones that shock
Total loss of muscle mass
Increased depression
Extreme tiredness
Strong stomach weight
Constipation
Swollen belly
Yellow stools

I feel like I’m dying, like I’ve lost the electrolytes and my stomach has “broken off”. I know it sounds absurd but that damned Vitamin D3 must have given me an Estrogenic version of PFS, I can feel it, I have something at the ER receptor. Otherwise my new symptoms are not explained. Cholecalciferol is transformed into Calcitriol the active form of Vitamin D3 and this appears to be an Aromatase inhibitor and a subregulator of the ER receptor.

See this study http://clincancerres.aacrjournals.org/content/clincanres/6/8/3371.full.pdf

The same thing happened with a Saw Palmetto PFS guy using Aromatis:
The symptoms he describes are practically the same and he even committed suicide.

The same happened to another boy Konflict with Vitamin E.

So I am not surprised if the same thing happened to me with Vitamin D3.
And the problems of connective tissue-collagen is due only to estrogen.

I don’t think it’s an increase in free Testosterone to cause me this.

Since the E2 exams are fine, I think about the ER receptor.
I really don’t know what to do, I thought to try Eutirox.

A dose that dose of Vitamin D3 was fatal.

I believe they are in the same direction as douglasmich.

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Stay away from damn vitamin d.

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Decreasing aromatization of steroids with vitamin D

Aromatization, in simple terms, is the process by which androgens (e.g. testosterone) are converted to estrogens (e.g. β-estradiol) by the action of the enzyme aromatase .

The aromatization of androgens to estrogens in the testes and extra glandular tissues of man is realized by the same enzyme complex present in the ovary and placenta, CYP19. The aromatization of androgens involves sequentially: hydroxylation, oxidation and removal of the C(19) with the aromatization of the A ring of the steroid.13

3 mole of NADPH and 3 mole of oxygen are needed to convert 1 mole of testosterone or androstenedione to estrone and estradiol, respectively.13 The oxidation in this process, involves a specific cytochrome P450 (CYP 19). Enzymes involved appear to be linked to a microsomal complex that includes the NADPH-cytochrome P450 reductase and cytochrome itself.13

From about 45 mg daily of estradiol produced in the body of a young male, only about 10 to 15% comes directly from testicular secretion, the remaining 85 to 90% are derived from peripheral aromatization of androstenedione (for estrone) and testosterone. 13 The formation of estrogens in the testes appears to be influenced by the levels of luteinizing hormone (LH) and human chorionic gonadotropin (hCG).13 Aromatization in peripheral tissues, although it does not seem to be affected by gonadotropins, increases with age.13

Vitamin D has demonstrated the ability to reduce the expression of the enzyme aromatase , primarily in adipocytes and estrogen-sensitive breast carcinoma.14 Moreover, in this type of cancers, Vitamin D decreases the action of prostaglandins in the breast tissue by suppressing cyclooxygenase-2 ( COX-2 ), elevating simultaneously 15-hydroxyprostaglandin dehydrogenase (which catalyzes prostaglandin degradation.)14 Prostaglandins stimulate aromatization, so they are major players in estrogen dependent diseases.14

Although this study was done in rats,14 the effect of the inhibition of aromatase in human seems a very plausible hypothesis with vitamin D. This work also showed an increase on the effect of aromatase inhibitors (anastrozole, letrozole and exemestane), when administered with vitamin D.14

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i used vitamin d3 like a year ago or something along with coq10,dhea,vitamin C,multivitamin, rhodiola and eleuthero… I think started crashing after using them didn’t really know if its possible they cause things like that but now I see im not only one :frowning:

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50.000Ui dose is completely crazy. Do you know that a maximum for a day is 2,000?

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How many units did you take?

I’m 100% dead from this. I have numbness of the whole body, totally insensitive skin, total dehydration, hypermobile joints! I wonder if I hypercalcemia or hypervitaminosis d? But I didn’t have hypermobile joints before the vitamin! This does not cause it! I feel my body totally lifeless I soon dead

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50,000 or 5000?

High doses of vitamins D is toxic. I think you should be consulting a doctor and having some blood tests before asking any advice from us. GO TO YOUR DOCTOR OR URGENT CARE! You have some very serious symptoms. Yellow stool? I had this when I was 10 in the hospital and almost dead after my body shut down from dehydration and sickness. Go get some blood tests man!

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50.000 ui

I very scared

I take 5000 recommended by my doctor but my cholesterol is high. The new recommendations have changed and most doctors are saying 5000 is good … but not 50,000!

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I believe it has nothing to do with calcium or parathyroid hormone. I have hypermobile articulations like douglasmich and even Konflict.

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You need to see a doctor. None of us are medically educated.

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i read your post man, first of all, chill tf out… eat a lot of veggies and fat and water… you will be fine.

use liquid vitamin D, K, A on skin only, not internal, never surpass 10kIU of vitamin D, your body only absorbs 10% of vitamin from skin, so if you use 50k IU of liquid drops on skin, you will absorb 5kIU if you rub it in, vitamin K/A is needed as co factors to vitamin D, you probably are just low on vitamin K, get liquid K2, A, and D, take only a few drops of K on skin, only 5k IU of A is really needed, here’s a good source of K2: https://www.healthnatura.com/TrueK2-s/1874.htm they sell D and A also

never take any supplement internal ever again, only take those above, use cronometer to hit your vitamin needs, also eat calcium (not a supplement), when you take D, it’s letting your body absorb calcium, if you dont eat calcium, your body will suck it out of your bones, which is probably what is happening here

vit D should be between 50-60 ideally, check it with bloodwork at yo docta

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there are so many different reasons for yellow stool. it doesn’t mean he is almost going to die. fear mongering is not a good idea.

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Yea let’s pat him on the back and tell him it will be ok while giving him medical advice and suggestions on herbs to take. Vit D is toxic at high doses. If you overdose on vitamins or supplements the last thing you need to do is get on a forum and ask medical advice from any of us.

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50.000Ui is way too much. I had very low vitamin D. Took 500 to 1000 in a day for a month and it went back to normal range. I don’t think Vitamin D is a good thing to play with. I am not a doctor, but even doctors say crazy things nowadays. IMO, people should not prescribe themselves more than 500 UI.

  1. Don’t panic
  2. Limit your calcium intake for a while
  3. Check your kidneys and gallbladder for stones after a while
  4. Don’t take high dosages of anything
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