Hi! This is Damon's Story


#1

Hi! This is my story

Where are you from (country)?
Italy

How did you find this forum (Google search – if so, what search terms? Via link from a forum or website – if so, what page? Other?)
Search for symptoms on google

What is your current age, height, weight?
27, 1.72, 56kg (first I was 63kg)

What specific drug did you use (finasteride, dutasteride, saw palmetto, isotretinoin/Accutane, fluoxetine, sertraline, citalopram, leuprorelin, etc…)?
I used Escine; Heparin; Saline diethylamine like ointment on the penis!

"Heparin", inhibits 5-alfareductase and antagonizes androgen receptors:

"Heparin-binding epidermal growth factor-like growth factor stimulates androgen-independent prostate cancer growth and antagonizes androgen receptor function." (Adam RM, Kim J, Lin J, Orsola A, Zhuang L, Rice DC, Freeman MR Endocrinology. 2002, Dec. 143 (12): 4599-608) https://www.ncbi.nlm.nih.gov/pubmed/12446587

"Because dihydrotestosterone was approximately 4-fold more potent than testosterone in stimulating basal FSH release, we examined the effects of testosterone in the presence of heparin, an inhibitor of steroid 5-reductase activity (Krzanowski and Troop, 1968; Steinberger and Fisher, 1971; Leveque and Grotjan, 1982). If the action of testosterone is mediated in part via 5a-reduction to dihydrotestosterone (or other 5a-reduced metabolites), inhibition of steroid 5-reductase should shift the testosterone dose-response curve to the right." (Interaction of progesterone with testosterone and dihydrotestosterone on follicle-stimulating hormone release by cultures of rat anterior pituitary cells. Leveque NW, Grotjan HE Jr. 1982 Aug;27(1):110-7) https://watermark.silverchair.com/biolreprod0110.pdf

In the topical compositions comprising the 5-alpha reductase inhibitors there is the other ingradient of the Reparil gel diethylamine which, among other things, also causes harmful effects on the nervous system. ( Topical compositions comprising 5-alpha reductase inhibitors, Dr Reddy’s Laboratories Inc Priority date 2008-08-21) https://patents.google.com/patent/US20100048598

Furthermore, Diethylamine appears to be similar to the structure and effect of Methyl salicylate, which blocks the production of prostaglandins and causes platelet dysfunction. " reducing the formation of prostaglandins, and cause platelet dysfunction." https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+1935

What dose did you take (eg. 1 mg/day, 1 mg every other day etc.)?
For 15days, I had the symptoms after a week!

What condition was being treated with the drug?
A reaction to the skin of the penis!

For how long did you take the drug (weeks/months/years)?
15Days

How old were you, and WHEN (date) did you start the drug?
28 June

How old were you when you quit, and WHEN (date) did you quit?
27

How did you quit (cold turkey or taper off)?
What does it mean?

How long into your usage did you notice the onset of side effects?
From July 3 onwards …

What side effects did you experience that have yet to resolve since discontinuation?
All!

Check the boxes that apply. You can save your post first, then interactively check/uncheck the boxes by clicking on them. If your symptoms change, please update your list.

Sexual
[:diamonds:] Loss of Libido / Sex Drive
[:diamonds:] Erectile Dysfunction
[:diamonds:] Complete Impotence
[:diamonds:] Loss of Morning Erections
[:diamonds:] Loss of Spontaneous Erections
[:diamonds:] Loss of Nocturnal Erections
[:diamonds:] Watery Ejaculate
[:diamonds:] Reduced Ejaculate
[:diamonds:] Inability or Difficulty to Ejaculate / Orgasm
[:diamonds:] Reduced Sperm Count / Motility

Mental
[:diamonds:] Emotional Blunting / Emotionally Flat
Difficulty Focusing / Concentrating
Confusion
Memory Loss / Forgetfulness
Stumbling over Words / Losing Train of Thought
Slurring of Speech
Lack of Motivation / Feeling Passive / Complacency
[:diamonds:] Extreme Anxiety / Panic Attacks
[:diamonds:] Severe Depression / Melancholy
[:diamonds:] Suicidal Thoughts

Physical
[:diamonds:] Penile Tissue Changes (narrowing, shrinkage, wrinkled)
Penis curvature / rotation on axis
Testicular Pain
[:diamonds:] Testicular Shrinkage / Loss of Fullness
[:diamonds:] Genital numbness / sensitivity decrease
Weight Gain
Gynecomastia (male breasts)
[:diamonds:] Muscle Wastage
[:diamonds:] Muscle Weakness
[:diamonds:] Joint Pain
Dry / Dark Circles under eyes

Misc
Prostate pain
[:diamonds:] Persistent Fatigue / Exhaustion
Stomach Pains / Digestion Problems
[:diamonds:] Constipation / “Poo Pellets”
Vision - Acuity Decrease / Blurriness
Tinnitus (ringing or high pitched sound in ears)
Hearing loss
Increased hair loss
Frequent urination
Lowered body temperature

Other (please explain)
To the penis: loss of sensibility, gumming, darker wrinkled and loose skin, glans wet! Loss of skin sensitivity of the whole body and gummy.

What (if any) treatments have you undertaken to recover from your side effects since discontinuation of the drug?
For now nothing yet! My mother believes me crazy

If you have pre or post-drug blood tests, what hormonal changes have you encountered since discontinuing the drug (please post your test results in the “Blood Tests” section and link to them in your post)?
Yes, after the problem arose…

Testosterone Total (4,59 ng / ml)
Estradiolo (29, pg / ml)
PRL (11,79 ng / ml)
FSH (5,6 mUI / ml)
LH (5,0 mIU / ml)
Testosterone Free (17,00 pg / ml)

Wait for DHEA-S, DHEA, DHT, SHBG.

Anything not listed in the above questions you’d like to share about your experience?
I do not know, you can ask

Tell us your story, in your own words, about your usage and side effects experienced while on/off the drug.

I applied ointment on the penis recommended by doctor to restore skin and, I exercised a perhaps too intense masturbation (maybe worse). The 4 July I wake up with a dead penis, atrophied that the smaller and less dense than it was normally in flaccid state; it is extremely very soft. The penis appears gelatinous and flat, if it is empty inside! So much so that it bends in every way and in all directions to make a knot and as if it were empty inside so as to appear extreme flat, I no longer have any sensitivity and feel a total detachment of the penis as if it were a foreign body, it is also very light and not heavy as it was before decadent to dead weight! The skin is loose and wide and burns, penis numb to the maximum none sensitivity to ice, the penis to the touch burns a lot. I have no libido or desire and no erection night or morning, manually they are very soft! Viagra (Rabestrom) does not work. What happened to me? I Scared!

What scares me most is the noticeable reductions in the penis, in length, width and fullness. The penis literally appears to be FLAT as if the fabric were missing!

I see a darker dorsal nerve respecting or how long it was, as if it were more darker (???)

Veins on the right side of the penis are dried

Now it is some days that I present the numbness and loss of touch and gummy skin to the rest of the body, especially hands! I lost weight and muscles

Unlike yours, I applied directly on the penis!
Reason for which I present aggressive to the penis

I would like to kill myself, all this is absurd.
Ruined by a shit gel!

Now I urologically visit, test the blood and look for a possible cure or therapy!

I will update!

Omar. (My name)


#2

Hi Omar, sorry that you’ve found yourself here.

Don’t kill yourself.

I felt much the same initially. I feel better now. You should know that lots of people’s symptoms get better with time.

Are you sleeping well? You will feel better if you try and reduce your stress. It seems that most people do better when they are calmer and rested.

I don’t know if there’s anything anyone here can do today to help your situation so you might have to just wait it out for a while. Hopefully someone will offer some suggestions though. Make sure you keep warm to help your circulation and try to eat healthy unprocessed foods. I would avoid prescription medication if possible, especially anything that is a 5 Alpha Reductase Inhibitor.

Please keep updating.


#3

Hi Greek, unfortunately I can not sleep and I constantly think there, with thoughts even obscure. I do not know if I can resist, even my body is leaving me, it’s really a fucking nightmare! Thank you for your solidarity, we must find a solution! I keep you updated


#4

You should try meditation if you cannot sleep. I know it is easier said than done. I still struggle to sleep but it is better than it was.

I prepare for sleep by doing yoga / stretches.

You can search YouTube for yoga stretches and for “guided meditation” which will show you what to do. If you can’t find anything, let me know and I’ll find some links for you.


#6

Ciao Damon!
I read your story, what a nightmare. I also have suicidal thoughts, my family want to close me in a mental facility.The thing is what is the point of living without hope? My only hope now is to wait if there is any cure, any solution, to try to educate and talk to doctors in my country, but I am not naive - certain things can’t; be regained…

At least you are in Italy - have some red wine, great pasta…Although personally, I feel that even if someone gave me a ticket for free now to beautiful Italy, if I feel like shit, I would probably not even care and enjoy myself…If your are shit, you are shit everywhere…

Take care Italian boy!


#7

Both our stories are nightmares and my family does not believe me! Thinks me’s crazy! We have been ruined by doctors, and while we are sick they laugh and live happily. It is simply a nightmare. If you come to Italy you are welcome, Asia! We make pasta and pizza! Take care of yourself, dear! :kissing_heart::kissing_heart::kissing_heart:


#8

Asia, where do you come from?..


#9

Hi Andrea.Poland, and you?


#10

Andrea comes from Italy like me :wink::wink::wink:


#11

Asia, come in Italy? We’ll have a pizza :smiley:


#12

hahaha, Damon, I am sure that if you saw me in person after Spironolactone you would not want to hang out with me at all :smiley: You would not even admit that I’m your friend - I look like your old aunt.20 years of aging in a couple of months. At least we can laugh about it, if no attractiveness, sex, or youth - then at least pizza and pasta is left…

PS. Do you have a girlfriend and how did she react to your problems?


#13

The same goes for me, I look like an old man now! Yes, really, the only thing we can do and laugh on and eat pasta and pizza hahaha! No, I do not have a girlfriend, but the person I love brought me to this situation. She knows everything. How did you react? He just abandoned me and did not care about me. I still did a good job not to make her feel guilty. And you? I ask you the same question :slight_smile:


#14

Hey man,
No, I don’t have anyone and now for sure I will never again have one, but at least I can be friends with people.
Sometimes my whole life passes in front of my eyes, just last year a was a fat young woman, and now I look so old and the skin is leathery and thin, I’m just praying if they can find a cure to restore some moisture and elasticity. Depressing…


#15

I know, the same depressing thing applies to me.
I do not know if there will ever be a cure.
We could hope for CRISPR …


#16

I look like this woman: https://www.instagram.com/p/BrQkHEznhVU/

Only her skin is more shiny and oily than mine.
If you want, you can PM your before and after skin pictures and I will do the same, but only if you keep it for yourself :smiley:


#17

Yes keep for me :slightly_smiling_face::slightly_smiling_face:


#18

@Greek my Damon’s Story has to be updated and rewritten, initially I was not sure what had caused the problem. Now I know. It is not this gel that I thought but Oxerutina. I will rewrite it.


#19

Yes Asia, as Damon already sayed, I come from Italy.


#20

:slightly_smiling_face::slightly_smiling_face::slightly_smiling_face:


#21

HI, @Andrea123.

It looks as if this thing is happening all over the world:sweat:
Do you guys have a trustworthy doctor in Italy?