I am deeply into this stuff, even trying to make an appointment with a doc in india to do it on me. Zadig didn’t do it, he wanted to, but never did it. There was a report on pfs from a guy claiming he knew another guy that tried it for 4 days, got ill, and quit. The guy could get drunk after these 4 days again. He said this guy tried aza, which doesnt cross the blood brain barrier, deca does. And also he did it only 4 days, and the real demethylation takes place the 2nd cycle, so the 2nd 4 days (u cycle 4 days with a week in between). On the pssd forum no one has tried, I have pssd and read the forums there. I just find it unusual no one has tried it yet while people are commiting suicide. On the other hand its extremey hard to get, so I understand. I think it’s very promising, especially knowing methyl donors worsen us. I also found an artical talking about epigenetic changes taking place after drugs use/during withdrawal, this happened to me too. "Co-author Fal Yadid, of Bar Ilan University, added:
'Surprisingly, we discovered that the biggest changes in DNA methylation occurred not during the exposure to the drug but during withdrawal.
'During this period of withdrawal, hundreds of genes changed their state of DNA methylation including genes that were known before to be involved in addiction."