For all those that can follow on the line of thought, that some form of silencing of the AR signal is at the root of our problem, there might be some hope. The main molecular mechanism behind persistent epigenetic changes in gene expression is DNA methylation. As methylation is also implied in cancer, much research attention is going into the question of reversing this process through demethylation via demethylating agents.
I would like to dedicate this thread to the subject of such demethylating agents. If anyone finds interesting information on the subject, please post it here.
A real “here and now” treatment option is Procaine (Novocaine):
If anything promising has come along my way recently, this is it. I am going to try to get my doc to shoot me up with this stuff.