Maybe I’m just being simple minded, but if you inhibit the AR with 5ari, the body will work twice as hard to make the AR work. Then if you stop inhibiting it, all of a sudden the AR work twice as much as they should.
If that is so, and if it reacts in the same general fashion as the rest of the body, you could weaken the AR by giving them less work over a period of time. Like a muscle that gets no exercise gets weaker.
Could that make sense ?
“The immune response is under significant regulation by the AR which is my opinion as to why we see immune related symptoms sometimes”
Tell me about it. I can’t eat carbs anymore and I’m reacting to all kinda food that I used to eat.
Maybe I crashed recently because of the DIM rich veggie juices I have been drinking for 2 weeks.
I just read “DIM inhibits DHT stimulation of DNA synthesis” so once again, I’m inhibiting what DHT was supposed to synthetise. That can’t be good ! http://www.jbc.org/content/278/23/21136.full.pdf
I was thinking of balancing my elevated cortisol with its antagonist: DHEA (which stimulate the production of testesterone and estrogen) but I think I will just stay away from anything, food, supplements, amino acids or drugs that has a direct impact on hormone levels.
Instead, I will just let my hormones play themselves out and my body find its balance.
At the same time, I will take the aminos that produces the neurotransmitters or neurosteroids for which I have symptoms of depletion, but not overly so and with pauses in between. Again, to prevent some conversion mechanisms from getting lazy yet at other times providing the precursors so that other conversion mechanisms, the next step over, won’t get lazy.
We always try to eliminate all the unpleasant symptoms but maybe some pain is inevitable in the healing process. (I mean just some, not all the pain)
Just food for thoughts…
Anyway. I find this prep improvement interestingly surprising and I wanted to be part of the thread so i can follow the developments.