New idea about our condition

Persistent infection(s) are always a possibility. However, I’m leaning toward the notion that antibiotic may have induced favorable, yet temporary, shift in microbiome leading to positive outcome(s). Newer studies suggest there’s a link between microbiome and inflammation/immune response. Gut dysbiosis may lead to Th1 or Th2 dominance via increasing inflammatory cytokines. I’ve witnessed similar experience trialing with various herbal antibiotics, prebiotics and probiotics. Problem is, it’s a moving target so results don’t usually replicate.

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Solid decision. Which fish oil brand are you on? I’m looking for one that has all the omegas (3, 6 & 9).

Isn’t fish oil a 5ari?

This is why I haven’t been taking it. Same reason I’ve been avoiding green tea.

Such a shame as both are wonderful superfoods

I doubt that fish oil is 5ari. Did not find anything related to this assumption at least.

Have you already got worse because of green tea or any other food ?

No, I haven’t attributed any food to worsening of symptoms thus far. In fact I used to be a big green tea drinker back in the day, but I’ve been paranoid to drink it for the last 3 years after reading EGCG inhibits DHT.

I felt a little better in certain areas years ago when I used to take supplements such as a b-complex multivitamin, but for a long time, I’ve been paranoid to take anything really.

Maybe I’ll start b-complex and drink green tea again. Also thinking of l-arginine for erections.

Any supplements you recommend?

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Fish oil is a 5ARI. Pretty much all poly fat is. Also, Ornithine is superior to arginine because it shuts off arginase.

Ornithine can also fix gout as it lowers uric acid.

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I think we should stop looking at everything as 5AR inhibitor. It will drive us all insane. We should try to look elsewhere. When we find cures as well try to find mechanisms of these cures. Not everything is just white and black 5ar inhibitor vs not.

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Based on my daily journal, there were high libido periods while consuming fish oil. Green tea is also anti-estrogenic. I think the 5ari effect is negligible depending on your baseline.

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I read that EGCG is good for blocking a certain enzyme responsible for peripheral l-dopa >>> dopamine conversion. This leads to more l-dopa crossing BBB and hence increasing brain dopamine (i.e libido). I used to take it alongside mucuna pruriens for this specific purpose.

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Thanks for the info sir. I just drank some green tea. Can’t go crazy with this theoretical 5ari stuff. I have felt a libido increase with it before like you describe.

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I did (and still do) keto and have been for 10 years to keep by body looking good. I take breaks but do it 6 months of the year. It only Mildly helped my PFS. By nature, ketones make you very clear headed and give you a slight buzz. The gym did the most benefit for my PFS and i pushed myself to go daily. I also have 2 massive drawers of pills from green tea, tribulus, arginine. Ashwaganda, … i tried 100 supplements and thousands of $$$$s. I also have a drawer full of things like clomid, cialis and AIs and proviron and 20 other chemicals and injectibles like peptides and hero’s. My refrigerator has HGH. After 10 years of this crap, The only thing that worked for me was injecting testosterone and testosterone ONLY! No AI’s no HCG … nada. No dhea … no handfuls of supplements. Lock the crap away and try just Testosterone for 3 months. It took 2 years to get my protocol and dosing correct and was by no means easy but now I’m normal. I inject every 2 days and the only thing I add Im is some HCG once a month to keep my balls atrophying but HCG messes with me a little

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Thanks for sharing your experience. Can you say what your T levels were before TRT helped you out?

Around 350 … sometimes 400. Free T was low and I don’t remember the number

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I leave you this protocol here.
Is quite similar to your hypothesis.
That guy was onto something.
I’m trying it, and i’m noticing an improvement.

https://forum.propeciahelp.com/t/just-my-thoughts-and-ongoing-hypothesis-continuously-changing-and-in-draft-mode-so-please-do-not-take-any-of-this-information-as-a-recovery-treatment/39408

This guys theory is very close to mine. I beleive it will work if we stay with it and listen to our body.

He also focused on a diet to apport 4 types of HDAC inhibitors through garlic, broccoli/cabbage, camomille and “food butyrates”.
If you look all the post carefully he connected all the system from inflammation to demethylation.
Is the most complete theory i’ve seen there. It simply connect all the dots.
Is probably the most underrated protocol of the board.

Im trying to relieve inflammation through a different way, im trying different peptides now both subq and intranasally.

Hey man, how are you going now?

I too am following a similar protocol. @Headsup really seemed like he was onto something, I wish there was a way to get in contact with him.

For what it’s worth, I had a consult with LeoandLongevity (check him out on Youtube) and this was one of the key takeaways I got from him.

“What happens in PFS is that short-term environmental changes (e.g. finasteride) cause long-term epigenetic changes. If I were in your position, I would optimize my use of HDAC inhibitors to encourage my epigenetics to change to reflect my new environment”

Very similar advice to what @headsup was advocating for.

Leo then goes on to recommend sodium valproate and Tributryin (sodium / magnesium / calcium butyrate). I personally will not be taking these compounds and strongly advise you to avoid them as well, just take a look what happened to Papasmurf after experimenting with Sodium Butyrate:

Personally, I will be following @headsup’s advice, optimise my diet to inhibit HDACs, reduce oxidative stress, and inflammation. Foods to focus on for inhibiting HDACs include:

  • Sulforaphane. Broccoli Sprouts.
  • Cooked and then cooled white potatoes. Cold potatoes are the best way to increase Butyrate in the gut.
  • Chamomile Tea.
  • Celery.
  • Garlic.
  • Ashwagandha.
  • NAC.

There are more (see study below), but these are the specific foods / compounds recommended by @headsup, they are also listed in the study.

Interested to hear how you are progressing.

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Thanks for sharing man. I agree, his banning was a shame and wasted potential. Good luck with your recovery and keep in touch. Cheers

How’re you travelling?