I read that EGCG is good for blocking a certain enzyme responsible for peripheral l-dopa >>> dopamine conversion. This leads to more l-dopa crossing BBB and hence increasing brain dopamine (i.e libido). I used to take it alongside mucuna pruriens for this specific purpose.
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Thanks for the info sir. I just drank some green tea. Can’t go crazy with this theoretical 5ari stuff. I have felt a libido increase with it before like you describe.
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I did (and still do) keto and have been for 10 years to keep by body looking good. I take breaks but do it 6 months of the year. It only Mildly helped my PFS. By nature, ketones make you very clear headed and give you a slight buzz. The gym did the most benefit for my PFS and i pushed myself to go daily. I also have 2 massive drawers of pills from green tea, tribulus, arginine. Ashwaganda, … i tried 100 supplements and thousands of $$$$s. I also have a drawer full of things like clomid, cialis and AIs and proviron and 20 other chemicals and injectibles like peptides and hero’s. My refrigerator has HGH. After 10 years of this crap, The only thing that worked for me was injecting testosterone and testosterone ONLY! No AI’s no HCG … nada. No dhea … no handfuls of supplements. Lock the crap away and try just Testosterone for 3 months. It took 2 years to get my protocol and dosing correct and was by no means easy but now I’m normal. I inject every 2 days and the only thing I add Im is some HCG once a month to keep my balls atrophying but HCG messes with me a little
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Thanks for sharing your experience. Can you say what your T levels were before TRT helped you out?
Around 350 … sometimes 400. Free T was low and I don’t remember the number
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I leave you this protocol here.
Is quite similar to your hypothesis.
That guy was onto something.
I’m trying it, and i’m noticing an improvement.
This guys theory is very close to mine. I beleive it will work if we stay with it and listen to our body.
He also focused on a diet to apport 4 types of HDAC inhibitors through garlic, broccoli/cabbage, camomille and “food butyrates”.
If you look all the post carefully he connected all the system from inflammation to demethylation.
Is the most complete theory i’ve seen there. It simply connect all the dots.
Is probably the most underrated protocol of the board.
Im trying to relieve inflammation through a different way, im trying different peptides now both subq and intranasally.
Hey man, how are you going now?
I too am following a similar protocol. @Headsup really seemed like he was onto something, I wish there was a way to get in contact with him.
For what it’s worth, I had a consult with LeoandLongevity (check him out on Youtube) and this was one of the key takeaways I got from him.
“What happens in PFS is that short-term environmental changes (e.g. finasteride) cause long-term epigenetic changes. If I were in your position, I would optimize my use of HDAC inhibitors to encourage my epigenetics to change to reflect my new environment”
Very similar advice to what @headsup was advocating for.
Leo then goes on to recommend sodium valproate and Tributryin (sodium / magnesium / calcium butyrate). I personally will not be taking these compounds and strongly advise you to avoid them as well, just take a look what happened to Papasmurf after experimenting with Sodium Butyrate:
Personally, I will be following @headsup’s advice, optimise my diet to inhibit HDACs, reduce oxidative stress, and inflammation. Foods to focus on for inhibiting HDACs include:
- Sulforaphane. Broccoli Sprouts.
- Cooked and then cooled white potatoes. Cold potatoes are the best way to increase Butyrate in the gut.
- Chamomile Tea.
- Celery.
- Garlic.
- Ashwagandha.
- NAC.
There are more (see study below), but these are the specific foods / compounds recommended by @headsup, they are also listed in the study.
Interested to hear how you are progressing.
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Thanks for sharing man. I agree, his banning was a shame and wasted potential. Good luck with your recovery and keep in touch. Cheers
How’re you travelling?
Hi Alex,
How’re the HDAC inhibitors working?
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Hey man,
i suppose you are headsup?
if correct, we can initiate a debate!
I hope you returned just to check the site and you still doing well.
Yeah I’m Heads up!
A debate lol…What about?
I’m feeling pretty good😁
i’m really glad for you! 
I couldn’t add neither brocolli nor camonille nor garlic. Just potatoes, meat and oats and almond milk. The rest crashed me heavily…
(i got really impressed to crash on those simplement foods)
My modifications are
Sometimes i use normal milk.
I do intermittent fasting
i have to take an SSRI
and i’m taking metformin, which lowers testosterone but degrades AR mRNA
i’m killing my recovery doing that?
Shortly after making that post I ran a microbiome analysis, the results were interesting - turns out I have the bacterial profile of somebody with chronic fatigue syndrome. My focus consequently shifted to fixing my microbiome and I have not been consistent with the HDAC inhibitors. I plan to run a course of HDAC inhibitors in the future, likely Tributyrin, Lithium, Beta-HydroxyButyrate, Raw Unmodified Potato Starch, and the foods I mentioned earlier, however this will be at a later date once I fix my microbiome. I don’t like taking too many things at once. Better to have one focus area at a time in my opinion. Good to see you back!
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did you try out your theory? Any results?
Hey yes keto is the way to go. I can’t eat carbs anymore as I get immediately stuffy and brain fogged and my dick goes cold.
I just read a study that backed up my theory. It states that tnf alpha and the eventual NADPH oxidase upregulation will directly damage the penis.
Interesting that suppression of TNF with a drug called Infliximab improved erectile dysfunction.
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I know nothing about this
Will this TNF damage the penis even in none PFS patients?
Are you saying poor choices in diet can actually make you worse apart from the traditional reasons why?