Androgen receptor overexpression and sensitivity to hormones reversed by epigenetic therapy that restores Pur-α to a transcriptional repressor complex of AR deregulated in HRPC

Lashes_to_lashes (RIP), someone with whom I share similar circumstances as he suffered from severe insomnia like I do and took resveratrol. Whereas I took a potent brand of cacao nibs for fatigue which contains resveratrol and quercetin among a crap ton of antiandrogenic plant phenols like that chart that stronguy posted. I was actually on my way to recovery from finasteride and wasn’t active on the forum when I took the cacao nibs.

Lashes took resveratrol for a few days, had better sleep then crashed and killed himself earlier this year. He was a good dude. Similarly my insomnia has been greatly worsened by cacao nibs for 9 months and counting now with no improvement.

That isn’t to say that I am not determined to get better and share the same fate as him as I often caught myself ruminating about that for a good part of the year.

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People are careful to point out how these plant based HDAC inhibitors are potentially dangerous substances to us. So no one is actually taking them beyond talking about hopefully, except for one guy here who loves his chamomile tea.

Hello Moonchild. I sent you a private message asking some questions. When you have time, could you help me? Thank you!

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Passing by to drop my little support.

Interestingly Melcani study in Italy found altered gut microbiome composition.
Butyrate is made by gut microbiome, my first symptom was sleep pattern alteration and lack of sleep ( sleep problem in general )

Butyrate, a metabolite of intestinal bacteria, enhances sleep

https://www.nature.com/articles/s41598-019-43502-1

I leave it to you guys to came up with your own conclusion.

Good luck

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Definitely a possibility, reduced allopregalone in the CSF makes more sense to be a bigger contributor in my opinion.

Doesn’t allopregalone help the GABA receptors function and they are responsible for sleep, reduced allopregalone might be why we struggle with sleep and muscle twitches.

Moonchild, you said in the topic below in March this year that you had recovered your erections and libido using tribulus and mucuna.

So did BHB and Butyrate only improve your sleep problems?

Would BHB and Butyrate also regain libido? I’m almost buying the brands you suggested plus a ketogenic diet, but I need to better understand your healing process.

I just want to recover from my sexual problems, and I don’t know if I try Tribulus + Mucuna or BHB + Butyrate.

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BTW, I found a study that suggests butyrate is a strong HDAC inhibitor, much more so than BHB. But together they may have a synergistic effect. I have some butyric acid caps coming from Amazon but it’s going to take a while, like after Christmas. I might want to expedite things by ordering butyrate salts elsewhere with faster shipping.

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Bro my account had been threatened to be suspended by moderators in this forum, I still don’t understand why, but I don’t care, the only reason I return back is to support with my experience those in desperate need.
Thank you :blush:

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I remember why:

Cause you kept shaming people who didn’t want to try experiments and wanted to wait it out

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Lakehouse, I never shame anybody, I never push anybody to any experiment, ok ?
The reason was clarified, was because a post that I did before posting about PSF saying that I should state ( I believe ) because users can take the post as fact…
You can ask [Dubya_B] if that is your concern.
And I will ask you a favor please do not talk to me, do not reply any thing to me, do not replay my post…
Anything that I post here is not for you…are we clear ?, put your nose where fit you better.

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Okay I’ll stop replying to you after this so you won’t be triggered by me anymore

:slight_smile:

EDIT:

after thinking further, i change my mind.

i will keep responding to you where i see fit @MOONCHILD

You know what, I will make zero post in this forum, I don’t need to be agraviated from people like you, I am feeling extremely good so I will going to live my life and it is very probably that you are going to stick for many years to come in this forum looking for a solution.

Bye

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Season of goodwill guys. Cut the bickering out. Any further posts like that not relevant to the thread topic will be deleted.

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Has anybody tried bicalutamide, or know someone who did?..

Moonchild, where you at Bro, are you missed here. How are you doing?

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I’m in contact with him he’s still doing good

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Ive stopped being vegan for months, been using bhb and eating meat + keto diet. Its even worse than before.
Sometimes its like some guys here think they have PFS but in reality they suffer from something else and that’s why they recover whereas their “cure” doesn’t work for people with PFS.
Back to vegan, the pain was less severe. I regret I tried bhb, keto, meat, …

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Bhb gave me bad anxiety @Xorack

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Do we have more people using BHB + Butyrate? What have been the effects so far?

@Xorack

Weren’t you doing well here with BHB? What do you have to say about progesterone? Is it still working?

Yeah I thought it was going well. But I was too optimistic as always when I feel better even for just one day.
I’m using progesterone 10 days a month, cycling. I don’t know what I m doing … I think I should stop trying to find my cure and let it go.