I am beginning to think more and more that addressing Allopregnanolone deficits might be the key to our recoveries.
Sage-217 looks like it will be great, but it’s at least two years away.
Has anyone here considered Etifoxine or Lithium? Both seem to increase Allopregnanolone a lot. At least one person on the PSSD forums has reported total recovery, after 10 years of severe sexual dysfunction, within only a couple weeks of starting Lithium. Etifoxine looks possibly even better for directly increasing Allopregnanolone.
I’m very interested in seeing what some of you think of these drugs and their use as stop-gap therapy ahead of the introduction of Sage-217. Trying them out might at least give us insight into how large a role Allopregnanolone really has in our syndrome.