Testosterone, dihydrotestosterone or 5ar2 antibodies.

I don’t care. Now it is established fact that Saw palmetto, finasteride, dutasteride, and accutane all cause the same effects.

That is not true.

If that were not true then why would Awors very own research proposal have 5ar inhibitors in the title and include SP, Accutane, etc in the body of work?

Shedding the hair might be genetics… like for me propecia didn’t even stop my hairloss at all.

Why would the “androgen system” down regulate itself after working fine for a “period” of time?

Also the samethings you mention here bring the androgen receptor down-regulation theory into question as well, unless you have a theory to explain alterations in androgen receptor activity occurring seemingly randomly.

Once again, I’m not saying this is it. I’m only saying its something that should be looked at, because it hasn’t been yet.

From what I understood, awor said there is nothing that indicates autoimmune disease. But, in order to 100% eliminate autoimmune maybe we should have antibody testing as part of the upcoming study.

only symptoms can be treated.

God bless him for his work on this whole issue, but are you really that blind to follow the advice of one man and only one man? He’s a smart guy but he isn’t solving this on his own and he’s not really a scientist or doctor as I know. Once again I’m not bashing the guy but for god’s sake have an open mind about this.

Every single possible idea should be pursued (unless completely absurd), especially those that have not been tested yet.

Bro easy with the pointless posts.

I assume his opinion is decided by his communication with the doctors and scientists who are in fact involved with the research. In other words, none of the researchers think its autoimmune. I could be wrong though, and I do suggest we include this in a future research so we can rule it out or not.

Bare in mind there is also a scientist in New York who thinks its some form of “withdrawl” from the finasteride…

Makes no sense to me but I suppose it could be possible in some twisted way as the drug does influence the central nervous system… however drugs that cause “withdrawal” tend to effect everyone… not just a handful of users.

I agree with Broken-Pecker. I have read several threads on this forum and what has escaped me is that lack of codification of symptoms. I really believe we need much more input with regards to the side effects experienced, duration, severity, etc…perhaps as objective as possible. I encourage everyone to be more involved, I sat on the sidelines for 5 months but now I am participating because it is important. Every angle needs to be explored. I asked under theories if anyone ever had a hyper sensitive reaction to cold weather, only 5 people responded! We definitely need much more input.

This is exactly correct. But I would like to add 2 things that make this idea superior to the other theory.

1. Autoimmune endocrine diseases are already known to occur. Permanent-Post-receptor-hypersensitivity-epigentic-changes to hormones are not.

2. This idea is quick and cheap and easy to rule out. We could have answers in a few months and move on to treatment options. The ‘AR theory’ is complex, time consuming and extremely expensive: and it may not even be possible to ever truly rule-out as a cause.

It’s well known that vasectomies can lead to autoimmune disorders and low testosterone.

It’s also well documented that when TRT is used in such cases it works very well - the opposite of what usually happens when we try it.
That is enough to rule it out for me.

Whats that got to do with Testosterone, dihydrotestosterone or 5ar2 antibodies??? I really worry about the quality of people on this forum sometimes.

Yeah, like you.

You mentioned autoimmune endocrine disorders in the previous posts.

Never mind, go back to your sad little world of trolling, shit theories and ruling yourself out of doing anything productive ever for the PFS community.

You should have been banned long ago.

Somebody direct me to where I can get these tests done. I have the money. Can’t sit around and wait for somebody to do something forever.

These are specialist tests and from what i can see, are not available in your average medical lab.
Such tests would need to be done in a proper medical research laboratory.

A potential option would be for the research to be organised by the PFS foundation.
That way, we could all donate towards the research costs rather than expecting one person to pay for it.

Any idea how much a test like this would cost?

You would have to find an institute that is capable of preforming the test, then tell them you could fund it.

Not sure what the cost would be, may not be too over the top as it is just blood tests.

He need to find a institue? Tim1911 and Oscar you are so deep in the autoimmun theorie and cant tell him where he can do a test??? Sorry, when I would be so sure i would have ckecked many institutes where he can go and write him the links. You guyes even have not ckecked what such things will cost? Are you kidding? He should do the work? for you? If you want to do something anything than go and help him seach a institute. Than you guys show that you are doing something and this shows just, that you have no clue, where he can make such a test and what it cost.