thanx Mew. Maybe then body create anti bodies against DHFin but can not diffrentiate between DHT and DHFin( both look same) and attack both at the same time. Since DHT binds to AR, AR also become affected. Maybe this is the reason when you stop the drug / start TRT feel short lived recovery.
Last question. Mew is there a test to detect DHfin in the body? What if liver can not break it down for a longer period of time?
Total IgE - 239 (range less than 100) 
Taken back in 09. I did not notice it on the paper.
Will try to retest.
4 out of 4 people with high igeâŚ
what lab tested you?
what these IgE are against?
high IgE means that all we have testosterone allergy or immunized to T or somethings similar.
That is nothing but speculation and opinion.
Provide scientific papers that state âhigh IgE means that all we have testosterone allergy or immunized to Tâ to back up your claims.
yes it is speculation, but not against T but against probably DHfinasteride. I really think solution is cleaning/changing our blood eith by
dialysis
blood donation.
read this
My test was total IgE in blood. As 4 out of 4 people have high IgE It would be good if some more people tested to see how consistent this is in PFS sufferers. It is hard to conclude anything from this. Maybe it could be an indicator to susceptibility, maybe not who knows. Lets keep the search for links going do not delay.
plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0014794
Conclusion
Our findings show that a sizeable subgroup of csU patients expresses IgE antibodies against thyroid peroxidase. These autoantibodies could cause âautoallergicâ mast cell activation, a novel pathomechanism of chronic spontaneous urticaria.
This indicates there is such thing as an IgE antibody for an enzyme.
antibodies-online.com/resources/16/677/anti-Immunoglobulin+E+IgE+secondary+antibodies/
all known antibodies test is required for a give us a hint about our illnessâŚ
scbt.com/table-testosterone.html
Testosterone Antibodies listed here and âIgG1â isotype not igE.
Good find. I think if you have high IgE its worth mentioning that study to a Doctor. Along with this study; ncbi.nlm.nih.gov/pubmed/21360500 that shows an autoimmune reaction towards an enzyme can be triggered by using an enzyme inhibitor. It also says that such a reaction is sustained after medication is stopped when the enzyme regenerates (in fact the full paper says such a reaction can get worse after stopping).
Hopefully that may be enough to get a doctor to order more tests.
People seem to suggest that 5ar activity is very high in the scrotal skin. It is weird that I have had a permanent red scrotum since finasterie. It is not some kind of external rash because I can see there is clear line of skin that runs though the center from the back that has no inflammation. The degree of redness varies but there has been persistent inflammation since taking or quiting fin ( cant remember exact time day it started).
after various crashes,i have vitiligo like hypo pigmentation-redness on my scrotum(there is nothing seen outside when penis shaft layed upon the scrotum,perfect 1-1 fit )-where penis shaft layed upon the scrotum area- most probably those immune cells attacked on my 5ar and scrotum pigments.
From what I can see here. EVEY BODY has lower than normal body temperature and low cortisol. The immune system regulates cortisol production. The immune system partly controls cortisol output â youtube.com/watch?v=ac0npV7dA70 Cortisol is immuno suppressive so it makes sense that the body lowers its production when it is trying to fight something.
There was also another mechanism mentioned in this thread as to how an auto immune problem could lower temps.
viewtopic.php?f=4&t=4208 - These are the temp logs so far. Everyone is low.
So we all have low body temps - low cortisol - everyone tested so far has high IgE. To me it looks quite conclusive we have some auto immune issue. Whether this is the root cause, I do not know.
I do know, me and others here have fully recovered for short periods. During my recovery I had very strong libido at some times, possibly stronger than ever. So I think our bodies are not damaged to a point where our libido has been âdeletedâ from our body/mind.
We need more immune system testing.
Most probably any GPO or Endo will not help. Google for companies which are manufacturing anti Testosterone, DHT , 5 AR anti bodies and then beg them to test you for antibodies. I think that is the only way
Almost everything that has improved symptoms on this board suppresses the immune system.
Isn;t it our body that would be producing antibodies? Why would we need to buy them?
the first day i take t4 for hashimoto thyroid, i felt better , and still i am in a better phase 2 months passed with my t4 meds, if i give up for 1 day i felt a crashh , think about it
Great post. I am currently working on getting immune testing done.