Can someone explain this to me now… How could dexamethazone even work…? If it suppresses the immune system, that means that it shuts it down completely, meaning it leaves your body open to other infections and stops the body from fighting the infection we may have as it is… I guess the theory behind dexa is that our immune system is attacking the prostate? Thats the only idea I see dexa helping at all… If i’m wrong in the idea behind this, can someone please correct me…
Sounds about right to me. The two ideas are surely mutually exclusive. Dexa (and the other Glucocorticoids, like HC) suppresses the immune system. Therefore if you have a bacterial infection (like Prostatitis) it will get WORSE if you take Dexa.
Could be autoimmune Prostatitis? Well thats not what Dr G is treating. Prostatitis may not even be anything to do with this situation.
There are a few stories of people getting better/improving with Glucocorticoids: if that is true (if, if) somewhere must be inflammed. I also remember Solonjk telling us that he initially remembered his genitals returning to normal size with hydrocortisone + Cipro.
Did you read his post completely? He is getting momentary relief due to anti-inflammatory drugs due to possibly prostatitis. And T4 is garbage and you shouldn’t believe a single story saying that he recovered with it. I have been using it for the past 2? years and i even increased the dosage during finasteride and have kept on with it. Obviously no recovery. T4 kept me functioning but didn’t prevent fatigue and brainfog which were due to something else (have had hypothyroidism even before finasteride)
Basically, it’s a temporary recovery. Or perhaps the guy was incredibly lucky and only had thyroid issues after finasteride.
I’d still advise that you USA guys consider if it’s wise to pour money on any USA urologists if you are considering to cure prostatitis. I’ve heard of some of their treatments even over here and they seems conflicting. harryp is from USA and he doesn’t know if you can get an insurance company behind this.
I mean i don’t want to push/patronize or anything but always consider that whatever money you use on other drugs, supplements and doctors/tests is off from the money you could possibly save for Georgiadis. That is if you want to beat prostatitis. You can let your parents know much beforehand so that they can consider this or that they could save money for it for a good time. Idk just some ideas.
yeah, sounds about right. I don’t know if you are wondering aloud the initial reason why this happened to us (i can’t tell from your post) but i do know that i cataclysted an ongoing prostatitis for me. It could be the same for others or that the finasteride for us weakened our prostrate to a point that the infections occured easily.
For how many of my symptons for me is due to this and for how many to others, i don’t know yet. Dunno if this helps the PFS symptons either too but i did have that arousal episode one day at the clinic plus solon’s and noniman’s experiences with sexual improvements so there might be something in this.
poga told me that at the beginning of his PFS the anti-inflammatories helped his sexual symptons. It was pleasant to hear, uh relieving in prostate angle… but yeah, not holding my breath over recovery ofc.
Don’t take cipro plus hc like solon though jesus. it was a mistake even though he improved for a short while.
basically, yes. I used hydrocortisone and T3. i had a recover of all mental + fatigue/weakness sides.
only thing left sexual sides and prostate sides
[btw. i just realized you already knew that via our PMs]
I believe that dexa is helping people in a different way. Read my “partial recovery + theory” here…
stress, anxiety, and binge drinking. all 3 of these reek havoc on the immune system. you were susceptible to a crash because your immune system was low.
my crash also came after a week of binge drinking (spring break). many others have reported that their crash came after a night of drinking or after stress. many also note that they had weird infections (candida, step throat, rashes, etc) show up right after/during this crash as well.
also, we were all likely genetically susceptible to prostate issues, and this crash/lowered immune reaction just allowed the prostate to inflame acutely. male pattern baldness = prostate inflammation. same mechanism. personally i have had a genetic test saying that i have the male pattern baldness gene and also have a 12% chance of prostate cancer (average male is only 6%, that is 2x the chance)
glucocorticoids (dexa, HC, prednisone) will only suppress your immune system if it (your cortisol levels) is normal. i think most of us realize by now that our immune systems are low.
In theory, solonjk use cipro and HC EARLY in his PFS stage, so his prostatitis was not strong as it was before he abused all those hormones…
Does Georgiadis give you a TRUS at the end of treatment to show the cleared/ reduced inflammation? or does he go on how you are feeling?
Or does he just let you go and you have to rely on his word that things improve over the next year?
This is a pretty important question in my opinion
He gave blasé a post treatment trus which was greatly improved, according to blasé
Edit: I meant noniman
I just want to share my personal opinion on the role of the prostate and why i think it is important:
-
I have prostate pain. Pain in perineum, pain where prostate is on anterior wall of rectum. This was confirmed on a PR exam
-
I improved about 20% on doxycycline which i took for a prolonged period of time. Stopping this as i have makes me get slowly worse
-
I feel worse when i have a full bladder or need to empty my bowels - one reason why if I lie in the morning i feel terrible - both bladder and bowel fill and there might be pressure on prostate.
-
Alcohol on the whole worsens things.
-
When i ejaculate i feel discomfort from my prostate - i can feel it contract. When i masturbate i feel discomfort below - feel this stops my penis getting as erect as it should. This actually makes sense because i can get harder erections if i don’t touch myself - as soon as i do the discomfort stops it progressing.
-
If i’m at home and sitting down all day i feel worse - if i’m walking about it helps.
-
My hormones have bar prolactin on one occasion been completely normal.
-
Taking tribulus gave me all around an androgenic boost but made my prostate pain worse and i felt awful with worsened vision.
-
Other treatments including xyrem, t3, prednisolone have done nothing really useful for me.
-
Solonjk and boston have both had major improvements. Solonjk has been here for a long time and there’s no reason to doubt him.
-
Prostate pain is not a feature of the androgen hypersensitivity leading to Ar signal downregulation theory.
So my experiences purely on a what works and what makes things worse basis point more to prostate as a cause. Whether it is a major symptom or root cause is speculation.
If other people report success or major improvement then i am willing to take the plunge. The difficulty is finding time and money.
Btw when on doxycycline it took 3-4 weeks to note real benefit.
So, Blase has finished treatment? that makes 4?
. Solonjk
. Gefauinuser (alomst)
. Nomiman
. Blase (?)
Not true (you remembered wrong but it’s okay). He does TRUS at the beginning and the end of the treatment. He can tell with his finger and the patient’s health alone how the patient’s inflammation and so infection is doing but the TRUSes are still important. I have seen TRUSes before and after treatment from at least two guys and they are certainly improving a lot after the treatment.
and yeah, should our condition is linked to prostatitis/from prostatitis angle, the anti-inflammatories takes weeks or MONTHS to work/improve you. decice if it’s worth it to put so much money on them ofc, maybe maybe not.
I thought Blase just started his treatment…
"Harry,
My best guess - having looked into the matter of semen variation - is that
your prostate is reacting to an attack or perceived attack (autoimmune
reaction)
I had the same thing you have, much lower volume and weird changes in my
prostate fluid, which makes up the bulk of your semen
I suggest you have your testosterone level checked and have a semen analysis
done. There is some chance that your sperm are being killed off when they reach
the prostate. There is also a chance that your semen is very alkaline.
I am over my prostatitis and my semen is returning to normal. I also had a
semen analysis done and everything is now in normal range and I have no
problems with my fertility.
I suggest you try Bactrim it works well.
A two month course of Dexamethasone, a rather powerful steroid, stopped my
prostatitis in its tracks (by the way I am not recommending this as a therapy
just reporting my own experience)
As I said I had the weird ejeculations including pure hot alkaline (salty)
watery muck ejeculations.
I assumed I was sterile, I am not.
I assumed that my prostate was damaged beyond repair and that blurps of salty
gray muck is all that I would produce for the rest of my life.
It has taken about three years for my semen to get back to normal (although
volume is still an issue) If and when your prostatis “burns out” look for your
semen to change for the better."
Taken from here:
medkb.com/Uwe/Forum.aspx/prostatitis/88/Fat-Bodies-in-semen
Of course, this is just an anecdotal report - but nevertheless someone else that in this case, found an incredible benefit from dexamethasone.
1 Like
the lack of communication/reporting of results from these guys (bar Solonjk) is not the best feeling…
Firstly, i don’t think Blase has finished treatment at all, infact i believe he has just begun. Secondly, why has there communication been bad? all 3 have gave us updates - if you read back you will see that nomiman is feeling better but nothing miraculous to report. Gefauinuser, hasn’t quite finished yet and again, nothing miraculous to report.
the lack of positive results posted + ambiguity of the posts some what worries me, that is all i’m saying.
This guy is going to be there in a few days, hopefully he updates us a bit more with clarity.
viewtopic.php?f=30&t=5326&p=40396#p40396
Well, in a couple of months there will be answers.
Dexamethasone is very interesting to me. Anyone else considering giving it a go?
If I could get a doctor to prescribe it to me, which is bleak…
thank you so much for the update. Lets keep this thread about updates from the guys in Greece. If you notice any dramatic changes please let us all know. Best wishes!
I find dexamethasone interesting as it is a very powerful anti-inflammatory. It is sometimes given BEFORE antibiotics in bacterial meningitis as when bacteria die they can cause inflammation in themselves. So its not mutually exclusive.
Also if it turns out antibiotics are not a be all this might prove useful:
jimmunol.org/content/177/12/8504.full
These data show a novel indication for vitamin D receptor agonists and indicate that treatment with Elocalcitol may inhibit the intraprostatic inflammatory response in chronic prostatitis/chronic pelvic pain syndrome patients.
Interesting to see vit D pop up. As vitamin D in itself is an agonist this might explain why some benefit on it.
It’ll take a month i imagine before any positives are noted.