The Key to Safely and Effectively Using Progesterone Cream
If you want to copy nature and reproduce a hormonal environment that most closely resembles a normal premenopausal woman the first logical step would be to get the hormones directly into your blood stream, just the way your ovary does.
Hormones carefully measured and formulated in an appropriate cream or gel need only be rubbed once or twice a day into your mucous (epithelial) membranes. Since there are no destructive detours through your GI tract when administered this way, your tissues are exposed to the appropriate concentrations of the hormone without the side effects of 30 different liver metabolites.
I first started using these creams in the early 1990s be became gradually disenchanted with them after I noticed that they typically worked wonderfully initially but then invariably stopped working. This is now known as “dermal fatigue”.
What happens, not only for progesterone cream, but for ANY hormone preparation you use by applying as a cream to your skin is that within a few weeks to a few months you will saturate the fat tissue with the hormones and they will actually stop working or can even make your symptoms worse.
The problem relates to the fact that progesterone is highly fat soluble and once applied to your skin will store itself in your fat tissue. When one initially uses the cream, there aren’t any problems as the fat stores are very low. But as time goes on, the cream accumulates and contributes to disruptions in your adrenal hormones such as DHEA, cortisol, and testosterone. I have learned that although progesterone cream is an enormously useful tool, it needs to be used very cautiously.
I found that many of the women who were on the cream have terribly elevated levels of this hormone. Progesterone is normally a cyclical hormone and the body really needs to see a change in the concentration to affect a proper physiological response. If the level is constantly above the concentration that it recognizes as “off” or low, this is not possible.
Fortunately, this is repairable. But it may involve going off the cream for as long as two years to wash the progesterone out of your system.
Best Way to Use Progesterone Cream
The key mistake that many well intentioned knowledgeable doctors, including myself made is to advise to use the cream on your skin. While this certainly provides better results than swallowing the hormones, it can still be improved.
There is a relatively minor tweak you can make with the creams which avoids nearly all of the side effects of applying the cream on your skin.
If you apply the cream to your mucous epithelial membranes that line your uterus and vagina you obtain a virtually ideal administration system. Not only is absorption through these membranes more complete than through your skin, but hormones absorbed through your vaginal membranes enter the very same pelvic plexus of veins that your ovaries normally empty into.
From here the hormones are carried to your heart and lungs and distributed to your tissues just as if your ovary had actually produced them.
Men also require hormones. Obviously men don’t have a vagina to use but we do have a rectum that has a similar mucosal epithelial surface and can be used to administer the hormones in a near ideal fashion without any of the complications previously described.