Progesterone treatment?

That has to be the best feeling in the world, seeing all that come back online. Very happy for you, man. :slight_smile:

How many people have tried selegeline? Someone mentioned that this is what the scientists were interested in?

to finatruth,so does this TELOGEN EFFLUVIUM hair loss grow back??? or is it lost forever like m.p.b???

Dgreene- I always wondered if it was the selegeline that kick starts the recovery process. It would make sense since its a dopamine booster and these recent studies indicate abnormally low levels o dopamine. I also have to admit, for the last few weeks I obsesse less and am much much more positive and have been getting unbelievable sexual functioning. There is a chance that just being positive and eating right will boost the process. Here is something else that is truly amazing, most people who recovered or felt 90% or so better, all had pretty positive outlooks or exercised and ate right etc. they seem to have the outlook from the onset of symptoms. I think that is quite telling. I believe I am one of the more positive people in this forum, and my last 6 weeks had been incredible with no real dips in orgasm, full sensitivity, and libido. If this syndrome is truly in our head which is what the research is showing, I encourage all of us to change our thinking to be more positive.

Robbo- IMO, yes hair will regrow. I don’t think it’s a coincidence that a majority of the people took this product because they felt like their hair was receding. However, effluviums are hormonal and can take forever to stop cycling. I am curious of how many who have this rapid hair shed are shocked by the fact that they are not bald yet.

Being positive is great, yes. Always. But what piece of research even remotely suggests that this is in our head?

the abstracts form the neurosteroid symposium indicating depleted progesterone metabolites in the CNS. Perhaps you were confused by what I mean, I didnt mean it was all in our head from a psychological standpoint, I meant form a physiological point.

ah gotcha.

Am I the only one here who has had a major improvement after 10 months? Meaning, erections are improving, energy and zest back, libido is near 100%. Have any of you had this for a sustained period of 4-5 weeks?

Maybe you are recovering naturally.

this is all from using progesterone right???,i felt that good on my first round of it i was thinking to myself at the time (did i really used to feel this good before fin) energy and zest were great,that is the only real improvement i have felt since the crash some 6 years ago…

Finatruth, I have had periods of 3-4 weeks(give or take) full recovery quite a few times in the past 16 months since I quit. Those happened mostly in the summer, on vacation (or post vacation) or at the beginning of a cycle of creatine/tribulus and such… So at least for me it has happened before several times even without progesterone. Because full recoveries have happened for me in the past, I’m reluctant to jump on the theory that progesterone could be a silver bullet for all cases… But I still think it is worth a try.

By the way I’m on the second day of my second cycle of being off of progesterone for about 5 days. The major things I have to report are that I feel slightly more energetic to get things done and go to the gym and also that on day 1 off of progesterone I had a nice morning wood that would not go down for at least 20 minutes after I got up. It has been about 8 months since that last happened to me without any cialis being involved in the process. I did have a few drinks the night before though and am not sure if this could have had some effect…

ncbi.nlm.nih.gov/pubmed/9058009

Progesterone stimulates in vitro release of prolactin and thyrotropin involving cAMP production in rat pituitary.
Tsai SC, Lu CC, Lau CP, Hwang GS, Lee HY, Chen SL, Huang SW, Shih HC, Chen YH, Chiao YC, Wang SW, Wang PS.
Source
Department and Graduate Institute of Physiology, National Yang-Ming University, Shih-Pai Taipei, Taiwan, Republic of China.
Abstract
Effects of progesterone administration in vivo or in vitro on the release of pituitary prolactin (PRL) and thyroid stimulating hormone (TSH) in vitro, as well as the generation of pituitary cyclic adenosine 3’, 5’-monophosphate (cAMP) were studied in ovariectomized (Ovx) rats. Ovx rats were either decapitated or injected subcutaneously with progesterone, or oil for 3 days before decapitation. The anterior pituitary glands (APs) of progesterone treated Ovx rats were incubated with Locke’s medium containing thyrotropin-releasing hormone (TRH, 10 nM) and/or 3-isobutyl-1-methylxanthine (IBMX, 1 mM) at 37 degrees C for 30 min. The APs of untreated Ovx rats were incubated in vitro with IBMX and progesterone (0, 0.1, 1, 10 nM). Progesterone increased spontaneous and TRH-induced release of PRL and TSH in vitro. Administration of progesterone, either in vivo or in vitro, increased the production of pituitary cAMP following incubation of IBMX. These results suggest that progesterone increases the release of PRL and TSH through a mechanism associated with an increase of cAMP production in rat APs.

I think what may be happening is that by taking progesterone, people are increasing their TRH and thus boosting thyroid function (hence the warm feeling, etc.). HOWEVER, TRH increases prolactin and prolactin inhibits GnRH which reduces LH, FSH, ultimately reducing testosterone and this is VERY bad (I’m wondering if this is the cause of the tired feeling many of you are experiencing). We DO NOT want to further deprive ourselves of androgens. So, for those of you who are experimenting with progesterone, you need to take Deprenyl (or a dopamine agonist) to increase dopamine and thus inhibit prolactin, thus preventing a reduction in androgens.

Nah, I am getting full of energy lately

Are you on progesterone right now?

No, just 2 months ago with 5 days on.

Progesterone inhibits GnRH and thus testosterone via prolactin while your on it

Did you use Selegiline at the same time?

I mentioned before that my T levels showed no real improvement from the four tests I reported. LEt me specify that they did adjust slightly. While on or just off progesterone they were in the low- mid Ts (213, 243). Two of the tests were taken while off Progesterone for a week: 293, 299. Small sample, and not a huge change but indicative of some T suppression, perhaps.