Mens Rea's Battle against PFS.

Dude, prog is a feminizing hormone… it is not the answer at all…

Here’s an idea: why don’t you move on with your life for the time being, accept that you can have sex with or even without pde-5s, be thankful you don’t have tanked hormones or typical wider PFS symptoms, and stop driving yourself to distraction and posting all the time.

Wrong thread (edit)

It can be when in excess, but it also have absolutely vital functions of cross-relation to DHT and E2. It balances against them. Why do you think Dr Hertoghe takes 100mg a day to control his e2? Balance of Prog/T/E/DHT is abolutely vital.

Do your reading, man. Many endos use prog to treat adrenal insufficiency, in fact.

Sorry but acceptance is not an option; only improvement and eventual recovery is. I am purposely building this thread as proof you can think your way through PFS by positive and systematic action.

You seem to imply this has side-tracked my life or something. That is untrue. This is on the side. I’m not stopping until im happy with my sexual condition. Right now my penis is smaller, thinner and i have ED etc. That is unacceptable at 25. I refuse to use worse-off examples of PFS to excuse my condition…because PFS is all forms is unexcusable. Sexual dysfunction and particularly genital tissue changes isn’t something you accept. Clearly, there’s something wrong inside my body and i intend to redress this. My E2 and DH2 are both dangerously high…i intend to redress this so far as feasible.

If my persistence irriates you then its probably because you need some of your own.

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Luckfax, your always saying the same old sob story about how your worse off than others. Give it a break.

Right and wrong. You’ll get feminizing effects only if progesterone doesn’t convert to cortisol, because, in that case, you will have too much progesterone floating around in your blood. This scenario usually happens to those males whose thyroid hormones are not high. If, on the other hand, you are supplementing with thyroid hormones, then good part of the progesterone will be converted into cortisol, which will give you energy and will downregulate the production of T. This will result in a decrease of E2.

In few words, progesterone is the healthy “feminizing” hormone that you want to have, not E2. Remember that, when you were young, you were not losing your hair because of your high progesterone. Then, when you grew older, your body downregulated the level of progesterone, which resulted in hair loss, which eventually lead you to this board.

Personally, I am taking transdermal progesterone every day (on top of thyroid medications) and I am feeling very good in terms of energy. When I first started it, my libido went up to 80% pre-fin. Then, it sadly went back down. But, in my experience, it’s one of the most “masculizing” hormones I’ve tried!

Yes, it’s all about balance.

It literally offsets against E2 and DHT to retain a vital balance.

It’s shocking that this board doesn’t know these things.

As you say cortisol conversion is very important but if anyone actually took time to look at the flow chart and educating them they’d also see it even downstreams to allopregnanolone for instance. Those vital downstream effects in addition to the necessary balancing of my elevated E2 and DHT makes it very logical to try prog (given pregnenolone was downstreaming the other direction as explained above).

A few slideshows from Dr Hertoghe’s teachings:

and

and

Solonjk has been to Dr Hertoghe, and he couldnt fix him either…

I’m not Solonjk.

Mens Rea, I thought prog is a powerful 5-alpha reductase inhibitor. So we’re going back to the scene of the crime? (serious q)

See my previous few posts about prog and the links.

You are right but it’s a perfectly natural 5-AR inhibitor and it’s a very important hormone to be balanced with T/E/DHT. The endoctrine system is all about healthy balance which isn’t what my levels exhibit.

Okay well things are still a bit weird.

I’m currently trying to find my “sweetspot” on the progesterone cream. Last night i tried 60mg (going up from 40mg) i.e. 3 pumps before bed.

I also took a doxy capsule for the first time. I decided to run it for 5 days as an experiment.

Anyway, i went to sleep and woke up about 30 minutes later with a very strange feeling down below. I felt a strong urge to urinate but i didn’t actually have to go. I got out of bed and looked down and my shaft was really thick at the bottom inch but tiny the rest. It looked deformed. I looked like the blood couldn’t get through or something.

I went to toilet but didn’t really need to go. I felt a tingling, what i would describe as tickly, sensation in my protrate area.

WTF.

I’ve put 60mg prog on again this morning and havent taken a doxy tablet yet. I want to find out which it was. I believe it was the doxy. If so, what is this telling me??

Honestly mate, asking the forum what this might tell you is completely unreliable. Any answer is likely to be totally wrong. The shaping of your penis which you just described happens to me all the time by the way, it goes very thin in the middle and normal elsewhere like blood can’t get through. Without an official diagnosis, there is no way that a person a forum can tell you what this type of thing is down to. It could be prostate related, it could be hormonal, it could be stress etc etc.

Some on the peyronie’s disease site call this the hourglass shape.

Take a look here if there’s a match. Warning: graphic photos (NSFW)

I had something similar to the top drawing. Natural Vit E helped.

i get hourglass too but in pre erection state
now when is full erect is not noticeable (3 yrs after crash)

after my crash it was also in erection

did u get penile ecocolordoppler?
i want to get one in order to understand if my penis has some kind of fibrosis

we have to better understand what kind of shrinl is occurrd

I have a urologist appointment booked for next Tuesday (private).

Just got those full bloods back from last time:

Testosterone: 40.5 nmol/l (10-30)
Oestradiol: 245pmol/l (<156)

FSH: 2.0
LH: 4.3

Prolactin: 54 mU/L (86 - 324) <------Cabergoline!!

IGF-1: 56.6 nmol/L (15-45)

A little strange that LH dropped a little despite Testosterone going up. T and E both at an all time high. Madness. That was two weeks after stopping arimidex.

My God, your Estradiol is crazy. Maybe you should call the lab and double check the reading. I have never seen one that high.

Your IGF-1 is through the roof. It’s much too high. Boston332 had the same problem, although I believe his level normalized somewhat now. If it stay high too long it can cause problems.

Mens Rea,

Have you ever taken a x4 saliva test? In theory, low cortisol should be the cause of your incredibly

It’s high but i have seen higher. I’m getting another blood taken this thursday id imagine it’s normalised a little <200pmol/L now ive been off arimidex for a long while. We’ll see. If not, aromasin will be taken for sure.

It’s definately an accurate reading. My others are 199, 196 etc.

No. I’ll try get a pm cortisol blood taken soon, though.

I’ve taken prog and preg without much success recently. I dont think i absorb well.

Anyway, urologist appointment this evening so that’ll be fun. Bringing with me a few studies and Dr Andrew Rynne’s (from Ireland) blog on fin just as a reference point. But i’ll be ultimately telling him im open to his direction and want him to explore everything really. Will report back later.