Well my T is in normal range as I’m taking only 40mg per week (plus HCG).
E2 is thus in range too. I know this from previous blood tests.
So, which hormones are ‘completely off’?
I received the Andractim 5 minutes ago and have taken it already. I agree I may not respond to Andractim.
I also cannot afford to go off everything totally, for the sake of my psychological and physical health. My symptoms before TRT were such that I, like ‘40’, spent my days trembling on my bed.
JN
You can try to mix Andractim with DMSO to see the difference
1gr DMSO and 19gr Andractim. Use one half at morning and one halt at bedtime. But I wouldnt use DMSO all the time because it transports unhealthy incredients of Andractim gel into the body!
Your input is appreciated cytochrome.
I’m sure DMSO does indeed improve the extraction of DHT. See wikipedia link:
en.wikipedia.org/wiki/Dimethyl_sulfoxide
However, I don’t see why this is necessary. The medical literature states that DHT metabolites are sufficiently elevated using the preparation it comes in. I’m happy to titrate dose to clinical effect, monitoring AdiolG and T4 levels (thyroid hormone levels can sometimes be effected, clinically unremarkable).
JN
DMSO primarily helps the DHT to sink through the skin and into the circulatory system. Don’t think it enters in to any reactions inside the body involving DHT.
JN, PM me privately on Andractim. kazman
ncbi.nlm.nih.gov/pubmed/1551803
Look, I think Adiol G is really important. Please have a look at this study. It basically shows that supplementing DHT is not going to necessarily increase 3AdiolG directly.
We need to get DHT to target tissues. I don’t think Andractim will do this.
Listen, Josh Fuller (he seemed to be the first sufferer before 2001) tried Andractim. It didn’t work. Others have tried Andractim. It doesn’t work. Elevating serum DHT WILL NOT really help.
Here is his story
propeciahelp.com/forum/viewt … avefulmore
What helped Josh Fuller? He said DHT injections made him feel good and gave him good erections. When I used Masteron, it gave me good erections and made me feel good.
I think our lack of androgenicity is 2 fold:
I think we need to raise Adiol G. I think we need an injectable DHT. Full stop. Kazman, Anonn1, Scardmale30, Mew and Awor…please respond to this.
We need make sure our adrenals are functioning properly.
PLEASE respond to the above. Emotion aside, our lives are moving quickly.
JN
Then what about cyclosporin? Have u tried this? It seems that all the approaches thus far you have taken are purely hormonal…
No, I haven’t. My only approach is ‘hormonal’. My aim (whether it be the correct aim or not) is to increase AdiolG to a normal value as this is the best marker of DHT metabolism.
Previous blood results have indicated my adrenals are ok. (High cortisol and low ACTH) although I will thoroughly eliminate adrenal problems with andrologist next week.
I respond to Proviron
I respond to Masteron
I am responding to Andractim, but insufficiently (I know it has only been a day!).
I am wondering about the dose of bioavailable DHT I may require
Please look at the DHT heptanoate study (type it in search). It required 250mg of DHT heptanoate to reach the TOP of normal DHT metabolites for one of the individuals.
I attach the following link for everyone’s perusal. You guys in the States, why don’t you get the telephone numbers of the guys who did the research (scroll down to the bottom)??? Beg them for information on how to say, increase AdiolG (ie) is transdermal gel good enough??
I’m going to make some phone calls later, but please chaps, pick up the phone and make a phone call. Intrude on their time, annoy them, pester them. They’ll probably enjoy it. It’s their expert field.
Please, don’t just read all this. Act now.
I should have Ann Conway and David Handelsman’s opinion next week.
They feature on the list.
I am still confident this is a DHT availability issue and am very interested by Josh Fuller’s report (from years ago) (His email address is strangely davefulmore@hotmail.com - if you type this into google, you’ll get a link to his conversation about Andractim not working, but DHT injections working well). This is KEY.
elitefitness.com/forum/bodyb … 00396.html
posted for my reference.
JN
Well, I’m sure you have seen the study, but from what I have read cyclosprine raises adiol g levels segnifigantly. If this is your primary goal, then why not persue this route instead of more and more trt based treatments?
I saw that one side effect of cyclosprine was hirsuitism, which, interestingly, is something that finasteride is used to treat. So perhaps it’s an avenue worth taking.
Cyclosporin is a potent immunosuppressant. It’s a good point Golf, but longterm use of Cyclosporin will cause increased infections and cancer. I’ve seen it used on patients. It’s a hardcore drug.
JN
I have read what it is - but if you do not currently have cancer i’m unsure it can cause it… Its used for transplants and dry eyes in it’s liquid drop form (note, dry eyes, another common symptom) but obviously it is your choice. If I was ten years down the road I would personally attempt it, at least a short period, and note symptomatic response.
Right, feeling ok on Andractim. We’ll see how it goes.
Get this. My skull has changed shape. When I took HGH, my occipital and temporal bones grew disproportionately, and stayed like it.
Then I took Masteron. My frontal and parietal bones grew, I swear, and I verified it using photos and by palpation. I stopped taking Masteron and the frontal and parietal bones shrunk a bit. Now I’ve started taking Andractim, (another DHT) and I swear my frontal and parietal bones are filling in somewhat again. After a day? (I hear you say)! Yes, I swear. After a day.
Further research has led me to the latest theory of hairloss. The causative mechanism for MPB? The skull growing. What is responsible for the skull growing? DHT. Where do men go bald? Over the frontal and parietal bones.
Where do they not go bald? The temporal and occipital areas (that’s HGH territory).
This would be fascinating if I wasn’t such a fucking human guinea pig.
JN
I agree with your second statement! Thats what I am trying to do. My opinion is, that Finasterid effects the adrenal system AND it effects 5arII on the receptor in specific organs.
So I try to let my adrenals work better and I try to highe my 5arII
I think that the lack of 5arII under Finasteid medication is the reason why adrenal system is altered in a wrong way. Healing the receptor sensitivity, forster 5arII via DHT shuts once a week and creatin monohydrat. And adding DHEA (only low levels). I feel good with this regime
Hey chaps,
Current regimen:
T 50 or 60mg per week
HCG 250iu twice a week
Andractim 5 grams twice a day
Vitamin D 10, 000iu per day.
Had blood levels done other day. T is normal 26 scale (9 to 55). So have increased T from 40 mg per week to 60mg per week.
I know my body intimately and clearly I am surviving ok with normal T. I believe the Andractim is holding me ok. Sexual function is obviously still poor and with Andractim, I see androgenic effects than Masteron, even less than Proviron. But it is holding me.
As previous chaps have noted, I don’t believe Andractim is the cure for this (cytochrome, Awor etc). I believe that whilst it elevates DHT metabolites (see scientific literature), it has a LOCAL effect (men use it for gynaecomastia, penis extension, even increasing beard growth). They use this topically.
I believe I need intramuscular DHT preparation. I have successfully filled out an access form for Mesterolone (1 methylated androgenic DHT) and will get the powder posted to me from China. Using the same supplier as where I got Drostanolone (Masteron from). Trustworthy.
I will formulate the IM Mesterolone in my kitchen. I have all the agents and apparatus.
I will stop Andractim and use IM Mesterolone. If it works, I will go about adding an enanthate ester onto the Mesterolone, to make it longer acting, so I don’t have to inject every day.
This is my last attempt to get better.
JN
Let’s use this thread positively. Everyone who has contributed to this thread needs to sign up for Dr Irwig’s excellent trial.
We NEED PEOPLE to sign up for this. WE NEED NUMBERS. Please.
It is easy. This is how I did it.
Print off the consent form. Sign it and fax it to Dr Irwig. The fax number is highlighted. If you have no fax, please email it or scan it to propeciastudy@gmail.com
Send an email to propeciastudy@gmail.com with your name and your telephone number.
It took me 2 minutes. Maybe 3 minutes.
THE DOCTORS WE RELY ON TREAT US NEED A SIGNIFICANT STUDY. We need this study.
Please.
I am desperate. I have a brother and sister who I love dearly but haven’t been able to love them properly for 9 years. I now live in a different country to them cos I ran away cos Finasteride ruined me.
I weighed 48kg in 2004 before I started TRT.
I have a lovely girlfriend I can’t have sex with because my dick is too limp cos of Finasteride.
Any of this sound familiar?
Every person in this study is a DIRECT stepping stone to getting this sorted.
PLEASE PLEASE PLEASE fill it out and send it. Yes, you. YOU.
My interview is on Monday 26th April. He phones me. Easy.
JN
This is the link. Do it now. Not tomorrow. You do it now.
Thank you, JN. This is the best post you wrote. I can comprehend very well your mood and really hope that all the users who are attentive to your story will follow in your footsteps and take part to this important study.
Bye
40
Dr Irwig is seriously qualified to lead this study. Here is his profile. Hopefully putting a face to a name will encourage some more participants.
JN
Reading my update are you?? Looking to see how ‘Human Guinea Pig’ JN is doing? Tactically logging in as a guest to see what JN has up his sleeve? Well, I’m about to inject what I believe the cure is. I have the needle right next to me and I’m about to plunge it into my right ass cheek.
I’m not updating my Recoveries section until Professor Irwig has received another 15 sufferers for his trial.
If you are reading this, and want an update on my potential cure, then you will be disappointed.
Please read this first
[b]
Spstriken, have you submitted your form?
Propeciasideeffects, have you done yours?
Fanjeera, I’ve been doing a load of research on sperm motility and I think I know how I can make your 99% malformed sperm into well formed ones.
I’m only going to contribute to this site when the study has been performed and adequate numbers have partaken.
Otherwise, what is the point. If you are reading this, and have not taken part in the trial, you are directing yourself in the wrong way. We need 10 more people to do what is so terribly easy…submit the form.
Now I’m going to inject myself.
JN[/b]
JN, I don’t know how r u healthwise but your brain has become faster thatn average guy.
No I did not submitted my form b/c I took Saw palmetto. If you think I will not distact Dr Irwig I will submit for suret. Indeed I thought many times to submit mine but I thought I did not qualify.
thanks
sps
JN, I recently e-mailed Dr. Irwig. Unfortunately, I am not eligible to participate in the study after disclosing to him my medical history.
Guys it doesn’t hurt to submit the form just disclose whatever you think makes you ineligible up front. The 20 seconds it takes him to review the case will not matter!