That’s if he’s able to maintain the recovery I’m hoping he does we have to wait and see.
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Ur receptors might be working, ours are not, for us the levels of testosterone and hpta matters nothing, i have had a perfect hormone level still i was disabled, plz try to understand this. It’s called pfs. Some have no other option but to try a stronger steroid that has much more affinity to the receptors than testosterone, that’s what he’s doing.
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Not here to argue, just educating newbies who might think this is a universal cure. Hope for the best!
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I am not at all arguing sir, i am just saying that the situation is not same for everyone here. Some have serious receptor problems that a level of even 1000 feels nothing, while u may feel awesome in that. I have had T/E2 levels of 585 and 32 in the past, still i was dying everyday. So we have very less options to even try. Plz don’t discourage anyone.
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Says who? I’ve used Propecia + generic finesteride for years and have deeply suffered for 10+ years. I nearly had every symptom in the book and more. Please don’t speak on my behalf. Journey to recovery was long and hard with too many dark turns and misfortunes. It’s everyone’s responsibility toward this community to warn others about a perilous treatment that may cause chemical castration. No one warned us about finesteride in first place and here we are, remember that.
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And u should certainly not speak behalf of every pfs patients. This is what u said regarding how u feel when u take exogenous hormones. I can vouch that 90% people with pfs don’t feel like their old self when taking testosterone but u feel like that. Having pfs and responding to something like testosterone is almost impossible for most people.
Comparing proviron and DHEA (which is OTC btw) and even full-blown testosterone to a chemical castrating compound like trestolone/MENT is pitiful. No one knows what PFS really is. 10 years later and here I’m still figuring it out. I also mentioned elsewhere that I was on cortisone + proviron on top of testosterone at the time. So, it could very much be that testosterone on its own wouldn’t have worked.
U have pfs since almost a decade? Were u responding to testosterone and proviron in early years of pfs?
In last year oct, i took a tablet of proviron and didn’t feel anything for 2 weeks, maybe felt worse, but then suddenly in 3rd week i started to feel my androgens strongly, i was functional enough to do anything, it lasted for a week. I don’t know why it took 2-3 weeks to show it’s effects when the half life of that drug itself is just 12 hrs !
Unfortunately, yes. Only time I had long remission were on testosterone + proviron + topical corticosteroid. Going off trt (and corticosteroid) resulted in symptoms relapsing. Proviron on its own didn’t do much, if anything. I still have bunch of it laying around. I think having chronically low E2 may explain why proviron isn’t working anymore. I’m experiencing all symptoms of high DHT:
- increased strength when working out
- facial hair growing faster than ever
- thinning hair
- aggression
This leads me to believe that more androgens is counterintuitive in my case. I’m not sure if testosterone would still be effective for me at this point. Trestolone may be helping because it raises E2 in unparalleled way.
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Ur androgen function is fine but estrogen is not? But what made u to be low on e2? U took finasteride right? I thought e2 problems only arise if we take something like that arimidex or aromasin, becoz these two drugs act on estrogen receptors just like fin acting on androgen receptors !!
I fuc*** up my body in so many ways over the years. Finesteride gave me high E2/low T & low DHT profile. I later did arimidex and aromasin to control E2, which initially worked and libido was fully restored, but eventually left me with low E2 since 2017. I shifted my attention to autoimmunity hypothesis. What’s your story?
I hope to god he’s going to recover I’m willing to try this sooner or later myself
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Alright guys, first of all, this is not a “recovery” thread. The only symptom that Trest helped was erections. It made them stronger and they did not go away as easy. Typically if I try to change position or lose stimulation, I could easily lose my erection. It seems to take longer for the erections to lower in strength now. I have only been able to test this solo though, as I filed for divorce and for some reason my wife doesn’t want to have sex anymore. My morning wood is def. harder too. But I am still not getting any random erections and my libido has not improved.
I actually have noticed that my flaccid penis also feels more full rather than hallow. I have been doing more IC / pelvic floor exercises lately as well (glute bridges, bicycles crunches, hindu squats) so who knows if that helps.
I have not continued taking the Trest beyond the 5 or so days I took it. Idk if it would make more sense to cycle it or just take it for a while. I am still taking 80mg test cyp.
Nothing else to note. I am actually planning on getting a penile implant in a few months, so this who situation kind of puts me into a conundrum.
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Thanks for taking the time to provide an update. I’m terribly sorry to hear about your divorce. Stay strong. Did you happen to get a bloodwork whilst on trestolone? I’m trying to build a hypothesis about its mode of action. It’s presumed that it favors T to E2 pathway and doesn’t convert to DHT.
Interesting…
Where did you read that Trestolone is known to favor the testosterone to estradiol pathway? This interests me because moonman like myself developed PFS from Saw P. I took dutasteride prior to taking Saw P and did not get PFS. This suggests that maybe even though the symptoms are the same that PFS from saw P and PFS from Fin or Dut do not have exactly the same mechanisms. And there is growing pattern of saw P cases improving from things that favor estrogen conversion
Those are some nice improvements and your experience sounds realistic. Instead of this vague story of “I took Trestolone and was cured”. Hopefully your results stick
Did you also get the other sexual sides such as poor orgasm, lack of sensitivity, poor semen quality and quantity?
Interestingly my experience from recent hops extract trials and my current 4 DHEA trial is similar to your experience in the regard that these things help with achieving and maintaining erections and “looking more full” during the course of the day. So far though the hops extract or my current 4 DHEA experiment has not been able to give me improvements in any of the other sexual sides though. Also I got even better results from my hops extract trials a few months ago with achieving and maintaining erections compared to what I am getting currently from my 4 DHEA cycle. I’m not sure if this is because hops extract works better then 4 DHEA for me or if it’s because I crashed from SAMe and amino acids during my hops extract trials and started this 4 DHEA trial after that crash. Hops contains a phytoestrogen which binds to and agonizes estrogen receptor alpha. There are two estrogen receptors. Era and Erb
So we both got PFS from saw P and I wonder if you would also get similar benefits from hops extract and 4 DHEA. If the answer is yes this further establishes a pattern
My pattern:
Do not get PFS from Dut
Get PFS from Saw P
Get worse from Clomid
Get worse from aromatase inhibitors
Get worse from zinc
Get worse from licorice extract
Get worse from taking Saw P again already in a Saw P induced state
Get worse from SAMe
Got almost completely better in all the sexual sides temporarily from mifepristone an anti androgen before fading back to baseline
Get improvements in some sexual sides from agonizing specifically estrogen receptor alpha with hops extract
Get improvements in some sexual sides from 4 DHEA which claims to increases testosterone and subsequent estrogen conversion through aromatase
Can you relate to any of these things ? Because a handful of other saw P guys can relate to almost every single one of these things. I believe that establishing patterns with “the different types of cases” is the key to getting improvements and not getting worse. It takes a lot of work, money, experimenting, documentation and organization though. It’s literally all of my time and money.
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I read on NCBI as well as Wikipedia that it doesn’t convert to DHT but converts to estrogen and Progesterone.
" Trestolone is not a substrate for 5α-reductase and hence is not potentiated or inactivated in so-called “androgenic” tissues like the skin, hair follicles, and prostate gland.[12] As such, it has a high ratio of anabolic to androgenic activity, similarly to other nandrolone derivatives.[4][3] Trestolone is a substrate for aromatase and hence produces the estrogen 7α-methylestradiol as a metabolite.[7][13]"
Studies are conflicting, as alwsys, but now that I read more in-depth about it, it seems it’s mostly converted to Progesterone. So, it may not be the best way to raise E2.
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This is good information . Especially the part about it being a substrate for aromatase
I would add a small dose of hcg, like 250 every 4 days and give it 3 months. Maybe you won’t need the pump.