I went from 1000 ui of vitamin D3 to 10000 ui of vitamin D2 and 1000 ui of vitamin D3. I’m seeing an improvement on my sleep. I wake up just as often, but I’m very drowzy, go back to sleep immediately and sleep is giving me good rest, so no fatigue in the day time.
I increased to 20000ui of D2 as well as 1000 ui of vitamin D3, also increased magnesium intake and the results were not so good. Nights were more hellish, feeling less rested in the day time. So I went back to a total of 11000 ui. I will test if half of that gives better results.
Vitamin D is often deficient in pfs sufferers (it is in me according to my blood test) and we need it to transform tryptophan into 5-HydroxyTriptophan (5-HTP) which in turn makes serotonine and melatonine (the sleep hormone !). It also takes magnesium and calcium for this transformation to take place.
No doudts, those suffering from anxiety and insomnia like me have a lack of serotonine, melatonine, dopamine, endorphine, allopregnanonlone and tetrahydrodeoxycorticosterone (WTF is that right ? It is synthesized from deoxycorticosterone with the help of 5α-reductase (oups) and some other stuff we have right). All promotes calm, peace, a sense of contentment, and relaxation and all are pretty messed up for those of us with the neurological symptoms. Apparently, the GABA receptors in the brain are also not working properly. Benzodiazepine like Alprazolam works directly with the GABA receptors, relieving both anxiety, insomnia and erectile dysfunction.
Allopregnanolone activate the GABA (A) receptors. Of all damage done by finasteride, allopregnanolone got the worst. Taurine can also help activate the GABA (A) receptors. I will try it.
I just noticed the protein shake I take everyday contains tons of amino acids, including Arginine, Glycine, Tryptophan, Tyrosine, Glutamine and all three BCAA, Isoleucine, Leucine and Valine.
To fix insomnia, I read GABA (250-750 mg) and glycine (1000 mg) work in pair to improve sleep. Some says 5gr of Glycine before bed works better (!!!)
Also read 5-HTP (normal people produce that from Tryptophan) and L-Theanine can fix insomnia.
I read elsewhere that taking all four of them plus Glutamine would fix insomnia. Those also helps for anxiety and depression. Add Tyrosine to the mix and brain fog should disappear.
@alteredlife also take L-Arginine and L-Citruline as well as Glutamine to fix sexual symptoms as well as muscular ones. Thanks to your success alteredlife, I’ll use aminos to experiment on the neurological symptoms (those are what curses me), and if we find a cure, I will pay your airplane ticket to Stockholm so we can go pick up our Nobel prize together. (ha ha !)
I should also note for those with zero night time erection and complete erectile dysfonction, if this is going on for too long you may end up with structural problems to your penis. We actually get nocturnal erections to prevent that. Good news, if you take Alprazolam it fixes that problem (although it’s another problem of itself).
I took Alprazolam for 1 month before being prescribed a less addictive sleeping pill, and during the time I took it, I was horny as hell, needed to have sex everyday, had strong erection and orgasm. All of which went back to what it was before when I stopped. So it’s not a cure at all, but it can prevent structural damage to your family jewels.