JQD what about a high zinc doasage (100+ mg)
at this dosage zinc act as an aromatise inhibitor,this will lower E2 and raise T level and reverse the estrogen dominance
i have heard that many doctors are using the zinc protocols for patients with estrogen dominance
I wanted to mention to the forum a new form of testosterone that has been discussed here. Testosterone suspension, it will be part of the next generation of this protocol, it converts to dht heavily and has no ester. The problem with pfs is we cannot handle esters, propionate has the shortest ester and so is this manageable.
After propionate is injected we still have to deal with the aromatization, with propionate it is just something we can at least manage. With testosterone suspension there is no ester, the shortest half life of any form of test and the closest to our own testosterone thus. We inject it, it will heavily convert to dht and leave our system even faster than propionate.
This means we will need less AI and have more benifits, I will be experimenting with it as soon as I get my hands on it, currently this protocol works and is the best we have. Iâm working on something even better, I want to maximize the pharmacology available to the best of my ability before I move on. I want to leave with the most efficient and effective protocol possible.
I urge you all to go on my protocol and anyone who can afford it do so with dr Jacobs so he can learn from this and study it and your test results. A better protocol doesnât negate an old one, I am fascinated with testosterone suspension ever since I have read about it. Moonman beat me to posting about it, I had planned on keeping it a secret, but since itâs out of the bag.
In a few months this forum will look very different, we wonât be debating what pfs is, we will be posting different methods of managing it, now that we know whatâs going on.
Dr Jacobs is prescribing my protocol, that is its own evidence, anyone can confirm that, so obviously he agrees with me. You can check with Recent Quitter who verified all this with dr Jacobs in a phone call by the way.
I believe that terminated your attack on me.Frustrated, if I have reversed this in myself, if others are improving based on my theories, if dr Jacobs is prescribing my protocol and intrigued with my research (per recent quitterâs convo with him) what is the root of your attacks on me? I am helping people here and you sre so blinded by your own ego, because you could not figure out how to respond to hormones, that means no one can? I have extensive knowledge in a field of hormones that dr Jacobs is NOT familiar with, most doctors are not. These are newer generation hormones used in anti aging medicine and by body builders.
I donât understsnd your point in attacking me? Is it your desire that no one tries this protocol? I have suggested people go to dr Jacobs and go on this protocol, why would I do that if it were not true? It has already been verified by others, so maybe you should just keep quiet.
Not really, because whatâs much more important than having Dr. Jacobs interested in some alternate form of testosterone is to have the drug produce real, lasting benefits. I donât know if Dr. Jacobs thinks it is worthwhile to try the 43,384th drug you landed on but its ridiculous to proclaim youâve found a magical cure when not a single person on here has said they have had a full and sustainable recovery.
This is not an attack, is it a call to reason.
Even though you claim to have extensively read through the forumâs history, several years ago there was a poster that like yourself started proclaiming he found the grand solution and that PFS was really a case of chronic prostatitis. Several guys followed his advice and sought out an intrusive treatment from a doctor in Greece who by all appearances seems to be a fraud. It was a pretty awful situation. We donât really know what the deal was, but your claims share a lot of similarities.
Separately, several years ago a website appeared with video of a hired actor selling a cure for PFS for something like $100. I donât know if anybody took the bait but $100 for the cure would be a price worth paying. The website doesnât exist anymore but since you are so smart you should be starting to see a pattern here.
This has nothing to do w/ me so donât try to make it personal. I do not have the relevant background to solve this problem and have cautiously tried different treatments. I remain open minded as one should be but you are throwing up red flags all around.
Are you well informed? If so why did you take it?
Now that you mention that Maybe we should find a way to challenge some endocrinologists that do not believe in this syndrome to take a DHT inhibiter. That way we can get one of these âcreditableâ doctors to suffer from this syndrome.
This is a pretty disturbing thing to say. At the time I first took the drug, I was informed mostly through the doctors I consulted. Merck is pretty cunning in how they go about selling their drug which is why they channel it through dermatologists rather than endocrinologists who are much more suited to understand the effects of Propecia. You took it many years ago as well when there was much less publicly available information about the syndrome.
I have not spoken with a single endocrinologist who doubted the potential dangers of Propecia, though I have not actively sought them out. I would expect most endocrinologists would be able to understand that using anti-androgens can have been serious consequences in at least some people.
5 alpha, let me explain, frustrated tried lots of hormones and never got them to work, so he has a lot of resentment towards me for that reason. There is a huge flaw in his argument and logic, one one hand he praises how great dr Jacobs is, and yet in the same sentence he dismisses my protocol and says he is âwearyâ of me. If in fact dr Jacobs is a great doctor (which I donât dispute) than him prescribing my protocol validates my arguments. His answer to that is that he doesnât know that dr Jacobs is prescribing my protocol, please⌠You canât attack me on one hand and praise dr Jacobs on the other and then not acknowledge that he is prescribing my protocol, stating that YOU are unaware of him prescribing it is absurd. Mew would immediately ban anyone making such claims if they were not true, this is all about your ego frustrated, you couldnât make this work and I could, and now you want to ruin it for everyone.
Frustrated, this can be easily solved, contact recent quitter who called dr Jacobs and confirmed he is prescribing my protocol and that he is intrigued with my research. If you are unwilling to do that then shut up, you are wasting space here. No one wants to hear your negativity and vitriole.
You are pretty dense. I have never said Dr. Jacobs is the greatest doctor, but I do trust him many times more than some erratic guy on here. I personally did not have a good experience with him along with many others. Like I said, there is a good chance he and Anne consider me one of his âtreatedâ patients which couldnât be further from the truth. If Dr. Jacobs thinks there is merit in your suggestions, let them be tested. There probably is not too much harm in referring people on here to Dr. Jacobs. Where you are going wildly wrong is you will not accept your one million approaches remain unproven, meanwhile you are manipulating the emotions of highly vulnerable patients.
I tried several hormone treatments and they did not work FOR ME. This does not mean the same treatments would certainly not be helpful to others. I am not resentful and I remain open to new ideas but no one protocol is likely to be the cure for all PFS patients.
By the way, Mr. Nobel Laureaute, the word is âwaryâ not âwearyâ. I am not growing tired of you but remain cautious about the incredible things you say. I realize this is petty, but honestly somebody who claims to be more of a technical expert than all of the specialized doctors should know the distinction.
I canât mention names, but many intelligent guys from here were against me till we spoke on the phone. I have a very deep understanding of this stuff, Iâll admit Iâm not the best at typing as I do all this on my iPhone hanging out downtown. My phone misspells things, you did not respond because you are estrogen dominant on a neurosteroidal level. With a fast acting and quick converting form of test we can induce your dht and get you going again.
I was non responsive for months, my protocols havenât changed, they have all evolved along the same theme. My principals have evolved and my theories have only evolved along the same theme, if you have followed me from day one, I have only figured out as I have experimented on myself. Look, whatever you may think of me, people are trying my approaches and imlroving and dr Jacobs is prescribing my protocol.
Iâm willing to explain it to you by phone in detail so you can understand if you are willing, pm me.
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Iâm on my iPhone, I post a lot and fast, I really think itâs ridiculous for you to be a grammar and spelling nazi, I have a business to run and a life to live. Do you think I would have been able to develop this protocol and help guys and get dr Jacobs to prescribe it if I spent time spell checking every post? You are being a jerk man.
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If heâs prescribing JQDâs protocol to others (no one has disproved this), then Dr. Jacobs either sees some value in it or heâs a pretty irresponsible doctor for following âsome erratic guyâ on the internet. Just sayin.
He doesnât care, he just wants to attack me, I mean why not? Maybe it gives him joy.
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Unbelievable that you can get this much typing done on your I Phone. JQD itâs obvious you are extremely intelligent. Dam anyone on here whoâs made It this far and more or less figured out that they have this syndrome on their own is no dummie. I honestly believe this thread does explain whatâs causing this syndrome. A strange type of estrogen domience makes sense. We are missing an important element as far as how male hormones are supposed to work because of are compromised 5 alpha reductase function. Because of this we are much more sensitive to estrogen.
Just curious frustrated, are you in med school? Somthing about your posts tell me you are⌠Itâs just a guess
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Iâm not in med school and donât really have much of a formal education in biology.
Frustrated, I know many quacks have come here and I understand your concerns, but try to understand that Dr Jacobs sees enough merit in my theories that he is prescribing my protocol. Surely that must mean something to you? That can easily be verified if you are a former patient of his, I wish to help you, not fight with you. My spelling and grammar may be off, but only because I sit downtown on my iPhone working and texting extremely fast on this form. I have said before that my brain works differently than others, I did not mean that to brag, it is a blessing and a curse.
I text on my phone as fast as I think, faster than I talk, people who see my text are often amazed, I have unique problem solving skills, I have made a living with these skills my whole life. I can solve all sorts of problems, it was bound to happen with this forum, someone would come along and solve this. I know what this condition is, I know how to treat it, my protocol is a prototype right now and it will give you the ability to have sexual function, a muscular body, and to feel normal.
I am working on perfecting it with testosterone suspension, the fundamental problem with this condition is estrogen dominance on a neurosteroidal level. I have the ability to see things in different ways than a normal person does, as a result of my brain working differently than most people, I have suffered my whole life with lots of depression and other problems. I was very much isolated as a child as I did not think like other little children, I thought like an adult, I have done a lot of things in my life that are difficult to believe. I was in a deposition with a famous politician and the lawyer deposing me went through all the things I had done in my life as though they were hard to believe, he tried to disprove them only to find out they were all true.
My mother was not surprised I found a treatment for this condition, I am eccentric and think differently, my texts come across arrogant, I know, but it is not my intention. If you heard my speak you would understand that it is just the way I talk, I am very blunt and straight forward. Stop fighting with me, let me help you, my messages on here may sound crazy to you, but I am inspirational to many here who may otherwise be considering suicide. At minimum my protocol is viable if Dr Jacobs is prescribing it, and my messages are intended to uplift people who are very much in despair.
I believe that I was given this condition so that I would solve it to help others, regardless of your beliefs (we all believe something or nothing), but that is what I believe. I have my whole life been in unique situations, and too many coincidences to be coincidences, a normal person cannot solve this problem quickly, it would take someone who is a bit crazy like me lol.
Let me explain again whatâs going on, I offer you my help, I will speak with you on the phone and explain in detail everything.
We took a drug that blocks 5AR, 5AR enzymes have jobs, as these enzymes reduce testosterone to DHT they perform these jobs, sebum production, male pheromones, sexuality, muscles, 5ar type 3 (ocular and neurological function). So there are an array of problems right there alone, those functions taken out create multiple problems, without these enzymes testosterone is aromatized. This is occurring on a neurosteroidal level which makes me wonder about depression in men, since this is undetectable on blood tests, perhaps many problems men and women suffer occur due to these estrogen levels in the brain.
So injecting testosterone with an ester creates problems for us, we cannot reduce it to DHT, the long acting ester exhausts our compromised 5AR system and estrogen becomes dominant. These are not âcrashes,â more accurately they are âestrogen attacks,â estrogen must be lowered and then DHT stimulated with a very quick converting form of testosterone. I believe the ultimate form of testosterone for this condition is testosterone suspension, it has no ester, it will rapidly convert to DHT and leave nothing behind to aromatize.
The reason testosterone propionate works is due to the short ester attached to it, so while our system has trouble, it is manageable, it was propionate that lead me to suspension. Propionate will work with arimidex, the key is to keep your estrogen levels low enough so that your DHT is not shut down and your DHT (which is an irreversible suicide inhibitor of estrogen) can kill off the estrogen. When testosterone levels are high in a male, they are converted to estrogen, when estrogen gets too high it signals the system that something is wrong and testosterone is out of control and in response the system shuts down testosterone, DHT etcâŚ
So DHT has a 5 day half life, estrogenâs half life is about 13 hours, the key is to continuously induce our own DHT and suppress our estrogen so that DHT can build up and kill off the estrogen. There are no real AIâs I have found that work well enough, I am currently testing letrozole for the 3rd time, I believe long term use could be successful, I am having very good success so far, I do not recommend guys follow my experiments who do not understand what I am talking about.
Propionate and Arimidex is my last working protocol, I am onto a better one now, attacking me for evolving is really a sad thing to do. Thinking in a confined manor does not help us and is why this condition has never been treated, it cannot be treated with the same dose of everything every day, you must modulate your treatment to your hormones. In time your system WILL recover, due to your past hormone use I believe you are in a cyclical estrogen dominant state. Guys here who used hormones and got worse did so because they did not control estrogen and then stopped. The testosterone cypionate (or whatever) created a feedback loop of estrogen dominance, it made it worse, so that so much estrogen built up it shut everything else down, when you stopped the hormones your own testosterone was compromised (and would have been anyway) but the estrogen was even higher.
Letrozole does stop estrogen aromatization in the brain as well, this interests me, I would like to work with you and help you, my protocol for guys like who who have been on hormones and have been off for years and are non responsive is as follows. Letrozole 2.5mg 2X a day and testosterone suspension (not sure yet of the doses and frequency till I test it out). In the meantime propionate with arimidex will work and get you back up and running, it will take time though, you have to constantly lower your estrogen and induce your DHT and allow DHT to build up, the more you induce the more it collects (remember it has a long half life of 5 days).
So you have to stop the estrogen cycle you are in and start inducing your own DHT, if all fails, I have a nuclear option incorporating DHT replacement that uses Masteron (however it must be used in a specific way with testosterone or it will not work, and it takes a month). I do not believe DHT replacement is necessary, I have witnessed first hand that my system recovered over time with this methodology, I have been operating off of these principals since I first got PFS. Before I knew it was estrogen dominance I thought it was some strange effect of low 5AR, I induced my own HGH via my pituitary gland using HGH precursor peptides and HGH stimulates 5AR activity which then starts the cycle of test reduction to DHT etc etcâŚ
I did not want to make this protocol too complicated, so I came up with propionate and arimidex, this way everyone can get on it and recover themselves till I come out with something better. Also, we need smart guys like yourself, if you were to learn my theories and operate off of them, you could reverse your condition and perhaps add to what I am doing here. I do apologize for attacking you back, I am going to stop responding to attacks here, but I take this seriously, also I am on testosterone, so I can roid rage lol.
I feel that I must help everyone here before I move on, it is why I got this, it is why this occurred, I cannot move on until everyone knows what I know. I told Dr Jacobs he can have all the credit, I donât care, I just want the truth to get out so this whole forum can change from trying to figure out PFS to perfecting the protocol. None of you have to suffer, people are already improving based on these principals.
This is bigger than a protocol, this is a principal, a concept, you can replace my drugs with others, you donât have to live like this. I understand how hard this is, I do, I was suicidal for a long time, but I have so much to live for, young, good looking guy, money, girls, nice car, nice body, I wasnât going to let this do me in. Estrogen takes over the brain and makes you crazy, when you get it under control things change.
I consider PFS to have 3 stages, PFS stage 1 (hypogonadism caused by finasteride but treatable with standard HRT). Stage 2, PFS that we all have here, and stage 3 is your state, cyclical estrogen dominance after testosterone use, it is fully reversible, you are NOT androgen non responsive. The theory that people here are androgen non-responsive is absurd, you are all responding fine to estrogen, it is a problem which has a basic cause and when you look at it this way it makes sense. It would be one thing if this was all theory, but I have reversed it in myself, and others are improving based on these principals.
This cannot be ignored, we must move beyond this now and get everyone reversed and perfect the drugs used to treat this condition, I already know several guys have started this via Dr Jacobs. Frustrated, put your criticisms aside and join me, what have you to lose? If Dr Jacobs is prescribing this, what have you to lose?
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Justquitdut- you donât have to defend yourself against these morons. Iâm not even responding to them and itâs getting tiresome.
Over one month ago, you posted this thread (in caps) called FINAL PROTOCOL 100% PFS REVERSAL WITH DHT THERAPY - LASTPOST. If that was true, why have you felt the need to âevolveâ since you have been âcuredâ for months already.
Much of what you say has generally been known to this forum. I personally am not âestrogen dominantâ and its pretty ridiculous for you to try to treat me over the internet without me having explained my symptoms to you or looked at any blood tests. I did the proper bloodwork, used arimidex (which you didnât know about till maybe 1 month ago) and saw that my estrogen levels were at the appropriate levels while I was able to increase the T/E ratio as desired.
If you ran these ideas by Jacobs and he thought they were not insane (especially your previous/current? protcol for taking way too much arimidex) then maybe there is some value to it. But Dr. Jacobs has made claims that have not been backed up before. He has said he has treated other guys on here, his nurse thought I had improved as I stopped consulting with them (completely untrue), and he even asked me if I was interested in going back on finasteride at some point (completely insane).
What Dr. Jacobs says/does is only significant if guys come back here and start reporting that they are having success. You can his most recent blog post claims he can cure all these different types of guys with PFS and I have literally not seen a single one on here that confirms his claims.
Finatruth - have you tried out any (at all) of these treatments JQD has suggested? If so, what has been your experience?
By the way, these comments about neurosteroids are somewhat known and somewhat off base. There was a research study put out in Italy close to two years ago about they are known to have an impact on mood and cognitive ability. Merely adjusting sex hormones will affect one branch of the chemicals that are disrupted by 5-ar inhibitors but they shouldnât be affect neurosteroids which have been demonstrated to be very impaired in a small sample.
Estrogen has little to do with the neurosteroids which are separate, but possibly very imporant molecules that are created by other precursors. It sounds nice to say you are âestrogen dominant at the neurosteroidal levelâ but doesnât really mean much.