I made a thread here about my arimidex experience. In the end I took 7mg per week. I stopped it cold turkey with absolutely no change in symptoms which was very surprising. Maybe I felt even a bit better.
@Invictus weird, I definitely have improvement but, it is not like first days of my usage first week i was hit by extreme fatigue but most of the pfs symptoms disappeared even ed. Then i make a break for few days now i am still okay but it is not like first week. Thank god i keep my restored libido and excellent genital sensitivity. I think i am either have too much estrogen produced while i had break or my testicular production has skyrocketed so i will not be able to crash it again. I will try and reduce the dosage in few days but, i want to keep this dosage until i see the endocrinologist.
And guys when you are on trt your balls will shutdown so you can easily crash with any aromatase inhibitor. I am not in any TRT i just use arimidex I already have natural high T production also i have high SHBG and low end Free T. I think This helped me because it boosted my Free Testosterone. We will see if doc orders a test.
A little update, I am on 1 or 0.75mg arimidex everyday my libido is not crazy high but I am keeping it. Also, i still enjoy having sex and kept my sensitivity.
I hope it will not go down further for one week it stabilized on this base level.
May be I crashed estrogen too much but, I intend to keep this until I make a blood test.
Any updates on you @VinnyG?
what about erection quality?
im not very improved, decided to increase test / stop the AI, also put on 6kg in a week lol
Well it fluctuated a lot in first week I got bone hard erections and returned to pre pfs. Then it went down but I was not as bad as before arimidex then it improved a bit.
Current status is erections are really hard also I can be erect via visual stimulation and I might have one shot without any problem but for second and third time I have to augment it with cialis.
Before arimidex 2nd time was impossible, I had to wait for 3 days minimum. At the moment i have more full erections but it is still hard to keep them.
Summary
Libido restored
Sensitivity restored recovered
Visual response turned back and improving
Lust for sex restored.
For Ed more hard erections than my pfs baseline but, still I have to support it with pde5 inhibitor for longer duration.
Most disturbing side effect is that my eyes have bloodshot and feels like burning all the time.
As of tonight I have started Tribulus.
@slick1 Hello Brother how is your situation is everything going okay?
I have started Tribulus Terrestis, i got my painful morning woods immediately before this, i got them with arimidex but, they were not waking me up, as a matter of fact they were but, only in my first week.
Now for several days, i got them again also, my libido further boosted. But it gives me some kind of rage and obsessive thoughts thankfully i can manage them.
My dosage 1 mg arimidex every night some times i take 0.5 mg. Tribulus 1000 mg day 1000 mg night 3.day only 1000 in the morning.
Plus 10 mg methylfolate 1g niacin 2g epa fishoil 20mg methylphenidate.
Hello guys,
I can confirm that for last 2 weeks my condition is stabilized it is not going worse or going better, I am unable to achieve the improvement of the first week but, i am way more better then my baseline.
I have sensitivity restored almost pre pfs level late ejaculation problem disappeared.
I am able to achieve orgasm easily with little concentration.
For sex One time at day, i have no problem with ED but second and third times i needed pde5 inhibitor. My visual libido is really perfect i am aroused by visual stimulation refractory period reduced to hours if not minutes. Spontaneous erections depends on arimidex dose which i am failed to find sweet spot for it. But nocturnals are back and i woke up with painful bone hard erections may be 3 nights every week.
My worst side effect is my burning red dry eyes second is little joint pain i can manage it with high dose fish oil.
My dosage for last two weeks is 1mg arimidex in workdays 0.5 mg in weekends.
This was the second huge improvement for me to since i have started modafinil / methylphenidate.
Yesterday i saw the endocrinologist he was very attentive and interested in my case but he says my case is above his head so he sand me to his boss and gave me most detail Endocrine lab test of my life he checked almost every thing except DHT growth hormone to somatomedin c acth to cortisol and dhae sulphate full mineral plus full liver enzymes and thytorid i will share results when i have them.
I got my partial results according to preliminary values even with 1mg everyday dose arimidex ineffective at the moment. This must be the reason about my failure of replicating first weeks improvement. Total e2 is 34 it was 35,5 3 years ago My total T went out of the charts⊠i will update when i got the other resultsâŠ
Okay i am still waiting for free T results i am sharing what i have now
Arimidex 1 month / Before arimidex
TSH 1.37 uIU/mL.
Free T4 1.01 ng/dL
Estradiol. 34 pg/ml. 35.5
FSH. 12.7 uIU/mL. 9
LH. 8.2 mIU/mL. 7.9
Prolactin. 15.2 ng/mL. 8.8
Total Testosterone 1230 ng/dL. 780
Free Testosterone
Glucose. 115 mg/dL
Insulin. 11 uU/mL. 7.9
Cortisol 9 ug/dL
ACTH. 12.5 pg/mL
Growth Hormone <0.05 ng/mL
IGF-1 113 ng/mL
DHEAS04. 238.5 ug/dL
Albumin. 47.2 g/L
Blood urea nitrogen. 17 mg/dL
Creatinine 0.96 UI/L
I think they lost my free T result or they confused with free T4
@VinnyG @Jaime @Invictus what do you think?
Should i change to aromasin for reducing estradiol to 22-25 range ?
Hey @DHT ! Where did you get this arimidex from? Is it an underground lab, or pharmaceutical grade? Iâve seen people on bodybuilding forums claim theyâve been taking arimidex and still have itchy nipples and high E2 symptoms. Then they check their E2 and it is very high (60) and they conclude itâs because they got sold fake, or ineffective underground arimidex.
Are you still taking 7 mg of arimidex per week? I feel like in most men, that would be enough to literally put you at an E2 level of 2. I have no idea how your E2 isnât tanked. I have two theories.
- You have mildly ineffective arimidex.
- PFS somehow is messing with your bodyâs hormones and has created a super high state of E2 that is only partially brought down by arimidex.
Also, did you test E2 via the sensitive assay? It is the gold standard and the most accurate.
Either way, I do not recommend aromasin. It is a irrerversible inhibitor meaning that your enzymes will be destroyed until rebuilt. That is exactly how I ended up here, taking an irreversible aromatase inhibitor. I know Iâm biased, but for that reason I donât recommend taking aromasin. Plus, the dosing and regimen will have to be retested and relearned until you know itâs safe to take.
The only thing I might recommend is trying to lower prolactin. I did that with cabergoline and it made me feel better while I was on it, but it wasnât really a cure. Again, thatâs a risk youâre willing to take and it might not be effective at all. As far as the very low growth hormone test, Iâve heard the gold standard of testing for it is the stimulation of GH test. Is that what you took, or simply a serum level?
I know your personal goal was to lower E2, but Iâm actually relieved you werenât able to achieve that because itâs really not safe to do so with the kind of dose you were taking. If you go to any bodybuilding forum and tell them youâre taking 7 mg of arimidex, they will think youâre absolutely insane. If you do want to take arimidex, be conservative and take waaaaay less. I know I sound like an old man harping away at your decisions, but Iâm just trying to keep you from really hurting yourself.
No judgements with whatever you decide to do, because it is your body in the end and I get that weâre all trying to find health again. But I just had to input that
nothing to worry about, beside your adex being bunk like others said
Lets hope not because if your free t is 1, youâd be immobile.
SHBG would be interesting to see as well.
Okay, Today I went to lab and yell them a bit.
They say my free Testosterone result is ready and just waiting for final approval. They send sample to another lab with a sensitive array i will summarize results down.
FSH 9 â> 12.7
LH 7.9 â> 8.2
Estradiol 35,5 â> 34 pg/mL
Total Testosterone 780 â> 1230 ng/dL
Free Testosterone 1.70 â> 4.61 ng/dL
Prolactin 8.8 â> 15.2 ng/mL
My first e2 and free T results are from 3-4 years ago others are from just a month ago Before arimidex.
It is really weird it I was sure that I had estrogen crash when I started arimidex at 0,5 mg per 2 days or 3 days also my ed was almost disappeared.
Then I made a break for a week then I unable to crash my e2 to that levels, paradoxically opposite of tiredness, I became more awake and extremely energetic.
Now also I have high rage, thank got my self control is also increased but, I really want to smash some thing
At gym my performance almost doubled I am using maximum weights on the machines I was stuck at %75 of max weights for three years. Now in 4 weeks, I max outed them easily.
I have very mild joint pain when I take arimidex.
I got some restoration on brain dick connection also visual lost restored a lot until this time I had bad days good days but these improvements are huge for me especially visual lust.
I am sure that arimidex is legal and taken from legitimate pharmacy.
Like you say may be I am unable to crash it because of pfs.l or my balls generating to much testosterone and overwhelms arimidex or some how my receptors became oversensitive.
I can confirm that I have weird tingling sensations on my nipples but I do not know if itâs related with estrogen or prolactin.
For short after one month of arimidex my testosterone almost doubled my free testosterone increased more than x2.5
Also my prolactin doubled for some unknown reasonâŠ
May be I have to add SERM to my regimen instead of changing to aromasin
Tamoxifen, Raloxifene or Clomifene. With Receptor blockade may be i can reduce my estrogen activity to desired levels.
Or maybe my improvement in first week only related with neurosteroid changes and i will not be able to replicate or sustain same improvement
Yeah thatâs so interesting. I do believe itâs real arimidex and effective because your testosterone went up significantly. But how you havenât crashed it is a mystery to us.
As far as the SERMs go, they can actually mimic high estrogen symptoms because they act on the estrogen receptors. I took clomid and it gave me high E2 symptoms, but my E2 never rose above 25. It took my testosterone very high (1200) too. Clomid and tamoxifen usually raise E2 due to the high test. The way I understand it, ralox doesnât âjump startâ the HPTA like the other serms, but is very effective against gyno because it binds the chest receptors tightly for some reason.
Im glad youâre feeling better, man! Fingers crossed that it is sustainable for you.
According to my free T level my SHBG must be lowered a lot because normal ranges of free T is between 0.1% to 0.2% of total Testorterone. Mine is currently in supra-physiological range at 0.4% of my Total Testosterone.
Even with these values, I only got partial restoration.
My biggest improvement was in my first week, when I was hit by low estrogen symptoms but got almost total recovery from Ed.
I was able to hold it up more than 30 minutes without the help of any pde5 inhibitor. I thought it was impossible and I basically returned before start of the my first symptoms, which is 10 years before today. I can do anything to replicate that achievement.
Edit
As of today I increased dosage to 1.5 mg anastrozole per day. @VinnyG @Jaime @Invictus
I have increased arimidex 2mg per day my libido increased proportionally but still i am unable to crash my estrogen though i feel like i got flu i think my interleukin 6 jumped because of crashed aromatase inhibition if i get an estrogen crash i will let you know. At the moment my nocturnals and morning woods increased also my dreams are sex oriented weirdly i got a lot of sleep disruptions because of painful woods. Everybody thinks i am on steroids or Trt because my muscle mass increased a lot also my upper body enlarged a lot according to papers arimidex should not have acted like anabolic steroids and gives more muscles but my strength almost doubled since the start.
I got 3 kg lean body mass even with fasting i gain weight but not as fat. Also i suspect water retention because i got a little bit moon face.
This looks very interesting
It seems logical that DHT concentration would increase concomitantly with elevations in TST because DHT is a TST metabolite. Relative to the change in FT and the significant increases in DHT over the eight-week period, the present data suggest a role for 6-OXO in up-regulating the activity of the 5α-reductase enzyme. Unlike TST, DHT is a non-aromatizable androgen
I think that is pretty much what is going on for tribulus, which does for SURE hold anti-estrogen properties for some, and why longer cycles are needed.