Cortisol management the key?

yeah you are completely right. thats what I THINK he did… not 100% sure or not. yeah i will be more on the perhaps side, my bad mew.

Bowing to the wisdom, yeah.

Ok i’m not going to push any theories any more. I do advocate finding what works for you personally, though.

The reason I’m taking a step back from this is because I just had an long phone discussion with Professor Bouloux about PFS and his views on certain things were quite enlightening. I’ll probably post his thoughts on all our theorys in due course. Obviously everyone has different opinions anyway though but i do think almost all of this board don’t understand certain fundamentals of hormones so its a dangerous thing to think you know more than you do. That includes me.

Agreed. Sadly, the same problem afflicts many doctors/specialists too.

The only people who dont understand ‘certain fundamentals of hormones’ are the jokers that keep on posting in this thread! :smiley:

TBH it was really my polite way of saying even the more “in the know” guys on this forum trying to formulate complex theories are the biggest of jokers because they’re writing about stuff they in fact don’t know what they’re talking about. The deeper their theories go the less accurate they become as they just aren’t at the medical level (or close) to what would truly be needed to try and make a blanket explanation of why PFS happens. It’s guys like Professor Bouloux who have well-balanced mindsets as they treat so many variations of sufferer (he has over 30 guys) and realise every patient has different requirements.

Even more interesting would be for you to get a full thyroid panel done while on prednisone. Assuming that:

  1. you are taking a large quantity (30-40 mg a day),
  2. you are not sexually ok (as it sounds to me)

then, according to this theory, your T3 and T4 should be low (as well as RT3). Boosting the thyroid hormones at the same time of cortisol, according to chilln, should increase your metabolism, which would make it easy (again, according to him) for T/DHT to enter androgen receptors.

Let’s just pack up and let the doctors do the theorizing for us. They are so abundant, well funded and eager to help us out. Come on, most of them deny the existence of PFS! The few that do haven’t done fuck all to discover what is afflicting us.

Aka we dont have a clue but let’s try a bunch of shit til something clicks. That’s not much different than what happens around here.

I didn’t say the reality was bright, did i?

Look at Mew’s other post in the theories thread, as he says, we need these top drawer scientists to really get to the bottom of things. Currently we don’t have those guys’ real attention and im not sure we will anytime soon.

Oscar etc

Here is something interesting from this thread which is words from Dr Crisler

On adrenals:

propeciahelp.com/forum/viewtopic.php?f=27&t=1092

He also says:

Interestings a again.

Interestingly that guy “Steve Richfie1d” said this himself:

I have no idea on this guys background but if you read the context of that he says his opinion is that whatever finasteride was changed into in our bodies (poisin!!) that when we we stoped taking this stuff our bodies attempted to make more of these similar hormones to cover the shortfall now that it has been desensitized, exhausts its reserves of hormoneprecursors, you go into “steroid hormone shutdown” as he called it. Dr Crisler said he never heard of it. It’s an interesting theory though and would explain crashes etc.

If you read on you’ll see he’s probably just making random theories but the gist of the actual theory seems somewhat possible. Worth a read, obviously changing gears a little here!

Ok just for the purposes of this thread i am putting in Dr Crisler’s quotes from his forum on this subject…

musclechatroom.com/forum/showthread.php?3611-Official-Finasteride-Thread/page22

Basically Oscar came over with usually attitude asking questions. Anyway, here is what Dr C says about preg/cortisol/Adrenal fatigue…

…so that confirms it. AF does appear to have a strong connection with PFS. I think alot of us suspected this already.

Dr C did also state in that forum that he doesn’t necessarily advocate any of Chillin’s theories (about DHT metabolism), this is hardly a shock considering what they claim.

Oscar has repeatedly asked for some basis as to why we think AF (and thus cortisol, preg etc is so important) well now you have it from the horses mouth. IT’S BECAUSE MANY PFS VICTIMS PRESENT WITH AF. So Oscar you can pipe down asking for sources and all that malarky, things regarding PFS are far too undeveloped , if we seen connections in individuals that’s atleast something.

Ironically, i’ve now lost my “small improvements”. I realise now it was the preg that had helped me, definately. After i try arimidex i might commit to more preg (bigger dosages) if i don’t get the results im hoping for with the arimidex.

Consider that he could have said something like: “Hormone modulation is far more complicated than Chilln thinks”. The fact that he didn’t is very meaningful in my opinion. Also, the fact that he never (to the best of my knowledge) contradicts Chilln’s posts is also something that I find surprising, considering that he completely trashes other people’s ideas, such as he does at musclechatroom.com/forum/showthread.php?3611-Official-Finasteride-Thread/page3 (there are many more examples of him harshly criticizing others’ posts)

Now, suppose for a second that he totally agreed with Chilln’s theories. Would he (or anybody in his shoes) acknowledge the truthfulness of the theory, and, most importantly, the validity of the hormone modulation therapy that Chilln proposes? Have you thought about what he’d earn and what he’d lose by doing so? Just food for thoughts…

To be honest im uncomfortable with people trying to draw inferences like that. I mean, it is what is. If Dr C, was in complete agreement with such a potentially ground breaking theory he’d write a paper on it.

Just take it for what it is. He uses Preg/HC to treat people he believes to have AF. Many PFS sufferers have AF which is probably not a coincidence. That’s the important part, really.

I’m uncomfortable too with people who try to draw inferences. That’s why I didn’t draw any conclusion in my previous post. I just clarified that usually, when he is in disagreement with something or someone, he clearly says it (e.g., his answer to Oscar). Regarding the open questions at the end of my post, there are many many possible answers to these questions, and they result in very different outcomes. Everybody is free to draw their own conclusion.

This is your own conclusion, which, as we both agreed, there was no need to share.

Agreed. This is the important stuff. Many people here are suffering from debilitating mental side effects and fatigue, which may be treatable by treating adrenal/thyroid issues.

This is no news. Crisler revealed this connection in 2008, and Mew posted it on a sticky. – viewtopic.php?f=27&t=1092

You’ll see i posted this earlier in the thread.

Oscar hasn’t responded since any of this has been flagged up. Maybe he should admit he’s been over-zealous in his campaign AGAINST this thread. He labelled it a “thread dedicated to your (my) ignorance”…i think it’s pretty clear who is being unhelpful in all of this.

I’ve put up a thread about something that has been PROVEN to help PFS sufferers (as agreed by Dr C), i think it’s quite important.

Well considering he’s openly said on numerous ocassions that he doesn’t have any outright cures for baldness and that he’s doesn’t know exactly what is going on with many PFS cases, then i think it’s pretty clear to conclude that his thoughts on the matters go much beyond “boosting the cortisol production line” as an all-encompassing solution to just about everything. Dr Crisler is a physician who could make many millions out of curing baldness and PFS if Chillin’s theory was completely true, i think it’s pretty safe to see what the situation is here. Be serious.

Lets just concentrate on what Dr Crisler HAS said instead of drawing inferences of his silence.

NB: This is not to say he doesn’t see some utility in this stuff other than for strictly adrenals, i’m just saying that it’s clearly not as black and white as Chillin presents it.

Actually, this was the thread to your ignorance: viewtopic.php?f=27&t=4945, but you can take your pick! :slight_smile:

As stated by myself, and more importantly Mew, it is unhelpful to post endless speculation without any sources. So its good to see that you have now dropped the whole ‘cortisol-production-line’ thing (I think you have anyway?) - but you must realise that the problem with it is that it is unsourced. If you had simply listened to me in the first place you would have realised that long ago!

His post didnt actually answer my question about that theory, which is unfortunate, and his actual answer seems to be some sort of compromise so as not to offend chilln. You can spin it in several ways. Unfortunately that has led to some confusion already! (Also, I have never read of Dr Cisler ever treating anyone for Adrenal Fatigue (whatever the hell that is anyway)).

I advocate fixing adrenal problems and the best ways of doing this is HC or Preg. Preg is a critical hormone. So, no, i haven’t dropped it if that’s what you mean. It’s been the most effective thing for my sexual function alongside cialis.

I’ve addressed the source issue perhaps 100 times now. Dr C has said his part - preg is very useful for many PFS sufferers. That’s a good enough source for me. The rest remains theory as it always was framed as. The rest is just your confusion on matters for no apparent reason.

Oscar, all jokes aside - you have symtoms of AF, you should atleast look at getting them assessed. ACTH stimulation test would be a start, alongside with all the bloods.

Figured this old info would be of interest in this thread, see the 17th post on page 2 of this thread, where I detail my experiences with topical cortisol, topical pregnanolone, and topical T:

viewtopic.php?f=5&t=1209&p=13254#p13254

It is worthwhile noting that the doctor who diagnosed adrenal fatigue and secondary hypogonadism had no idea PFS existed (and at the time neither did I).

After doing more extensive research, I decided I would need to increase my Cortisol again. I’m tyring to figure out what the threshold is in terms of mgs per day. I listend to a audio that someone posted a while back in which Chrisler was talking about this subject. I believe he said up to 40mg per day. Can anyone confirm that?

I definitely think I need to go higher than 20mg to stabilze my temps.

I initially reported having erections in the middle of night once I started the HC. When I weaned back down to 5mg, the night time erections went away. I now am back up to 25mg per day. The past few nights I had erections every night. One even mad it a little difficult to piss.