Cortisol management the key?

Ok this isn’t a coincidence. This week having used preg ive had the best quality and amounts of ejaculate in a long time. Higher libido too. No miracle changes but very notable. I’ve got no doubt there’s connections here.

I know this sounds a little lazy, but i don’t want to have to rely on putting a cream on every morning for the rest of my life. Don’t get me wrong if it got me back to 90-100% then i would, but buying cream etc for an extra 10-15% isn’t really something that seems feasible long term.

I’m going to try the arimidex and see if when i get my e2 levels down if i become more responsive to this stuff.

I had that too… then it all went away…Our bodies are not stable… to much inflammation… to much shit gone wrong…

I actually think people’s improvements dwindle because they (generally speaking) aren’t fixing the root issues.

I mean, you could increase libido in ANYONE with a tablet of proviron for instance. So just because someone with PFS feels “normal” again on proviron for a while, doesn’t mean much because what they are enjoying is a temporary articifical boost (beyond their new “base”). You aren’t actually fixing your base levels whatsoever.

In terms of this, i’ve no idea why your progress fell off. It may be due to lack of T3/T4? Either that or maybe your cortisol levels arent in fact the problem? OR lastly you need to address something else concurrently otherwise you’re tweaking one part of the puzzle but still straining your endoctrine system on another disrupted path.

The body i suppose will put up resistence as we’re supposedly “stable” in our new states. To “restart” we need to reset all problematic areas. Somehow…

Yep, I need to boast my thyroid hormones as well… Just waiting to see Crisler… Trying to ween myself off HC… im only taking 10 mg a day… Honestly I dont see a point in weening off them with me bcause I feel the same regardless if i take it a or not…

Probably. If you increase your cortisol (via pregnenolone for example) without boosting your thyroid hormones, then you will run out of thyroid hormones and your improvements will disappear – it happened to me too. There is not such a thing as “developing resistance” to pregnenolone. Therefore, you should consider the weening off of the improvement as a step forward, not backward – you fixed a problem, and another (a solvable one) has arised.

More than a “resistance”, it’s a change in other hormones I think.

I agree. Hopefully, we’ll be successful…

I forgot to include another case from one of our members, which further confirms the importance of a healthy cortisol production line: [b]correiovip /b.

He has been using prednisone for allergies, once a month for a year or so. He says that every time he took it (and stopped it) he was feeling overall better. He reached a point where he claims himself recovered, under all points of view: energy, metabolism, libido, etc… He also attributes most of his recovery to prednisone, and the rest to diet.

He seems to be one of the luckiest cases, as he only needed to boost his cortisol production line to improve so much. All other examples reported in this thread (Dury, JN, ithappens) needed to also address other hormones (T or GH) to reach a satisfying sex life.

m-81 - would you mind explaining how taking prednisone affected his cortisol production line? I’m confused by the connection. Thank you!

Here is an excerpt from the “guide” to boost one’s cortisol production line (link below). This passage compares the use of hydrocortisone (HC) to the use of medrol / prednisone / prednisolone to boost one’s cortisol – it says that HC is preferable, but both work.

[i]Medrol / prednisone / prednisolone are cortisol molecules which have added or substituted molecular fragments which cortisol does not have. These added or substituted molecular fragments ensure that medrol / prednisone / prednisolone is more slowly metabolized into downstream metabolites than HC. The interesting thing about medrol / prednisone / prednisolone is that it triggers many cortisol metabolism processes even before the added fragments are removed / metabolized.

This is why when medrol / prednisone / prednisolone is used to supply a person’s complete daily cortisol needs, the overall dose of medrol / prednisone / prednisolone is less than a person’s daily production of cortisol.
[/i]
http://www.musclechatroom.com/forum/content.php?118-cortisol-boost-101

Yes, I believe that’s the problem with many of us. We simply think we can take the thyroid meds and be better. It’s far more complicated. First your adrenals need to be working properly, in order for the thyriod hormones to even work. We should also be factoring in Vit C, Vit D, Vit E, Selenium, Zinc, Iodine, Vit B12/6. Many of these are an issue with hypo people. Some of these play a critical role in thyroid hormones gettin to the cells.

This thread is labeled, “Is Cortisol Management the key?”, but I don’t see any one mentioning being on HC treatment. Has anyone been able to stablize their body temp? This is critical in order to work thyroid hormones in. I have not been able to achieve this. Anyone?

I have mentioned it as have others. I’m interested in people’s experiences with HC, too.

Around a year ago I did a two week course of prednislone and noticed no improvement on it.

along with ferritein and iron and all your electrolytes in general…as to why those are so fucked up in a lot of us… i have no clue.

along with cortisol… isnt your body temp also screwed up when you have too much RT3 in your body? i was reading an article on RT3 and the doctor said that you dose T3 until you stablize your body temp, then you know you got rid of RT3 or something along those lines… buuuut if cortisol is also messing up body temp, then that can be an issue.

not sure if both effect body temp. i know cortisol does… RT3 might… that could be the reason why you cant stablize your temp…

Uhhhhh. What JN did was exactly that: he got a full thyroid hormone panel + 24 salvia test + took temperatures three times a day. Noticed that his adrenals/thyroid is out of whack and the Reverse T3 showed up to be high - ergo, he started taking (just/plain? i’m not sure whether he managed to clean himself out with armour though as that has T4. check that bit out!) T3 in order to first empty RT3 then he started his hydrocortisol and T4 and T3 respectively.

How to take temperature properly and how to analyze the results: http://www.drrind.com/therapies/metabolic-temperature-graph#directions. Everything in that site is really good and there is stuff about supplements to take for adrenal recovery.

What i’m REALLY concerned though is his reasons for dropping cortisol and thyroid entirely (and how it is working out)… or more importantly, what the heck are the other treatments he is doing right now?!

I believe JN takes a injectable B12 and says that he gets great benefits from it, though i don’t know if it’s because of the boost to thyroids. http://www.drrind.com/therapies/adrenal-support-recommendation-sheet Here’s a good list of things to take for adrenals. Still, it will be hard to know what we are deficient on.

I’m not on HC yet as i need to first get right tests (salvia, temperature, large thyroid panel) in order to get a diagnosis of it. Everything in this friggin’ country requires prescription and it’s lucky that those three don’t (private sector, non-prescription). Just money which i’m pretty deficient upon. :laughing:

from what i understand, once you start using these, its used to jumpstart your own thyroid panel. so the reason he dropped T3 was because he got all the RT3 out of his body. And the cortisol levels, you bring your cortisol back up with the supplementation, then you are supposed to slowly wean off it, and your adrenals pick up the slack and continue to make the same amount. that’s why im suprised JN was able to just stop it completely, but he said he did it over 2 or 3 days, so he slowly decreased the doses and his adreanls picked up the slack.

I see. Sorry if some of this is false theorizing but i’m doing my best to learn about this stuff. Looks like my fight with hypothyroidism is far from over regardless. Grrr.

I GUESS the body stops to convert T4 to RT3 once the RT3 is out… only if you don’t have problems with your T4->T3 conversion itself from the beginning with? I mean JN sure didn’t supplement synthetic T4 from the beginning with, unlike i have. My part might be harder as i have been on 50mg T4 for a year already, even prior to finasteride. It did help me out but since no antibodies weren’t taken, i never got to know the real reason behind it. Apparently the thyroid HASN’T decreased or increased in size or anything when it was scanned in ultrasonic which was mysterious.

I wouldn’t wonder if my body has been converting the excess T4 to RT3 all this time because of PFS. I have been hypothyroid since high school without me knowing it and both my brother and mother are hypothyroid too. A strong genetical thing!

So the trouble will be to get to know what is up with my thryroid. Man, looks like i really need to find out properly what’s going on with my thryroid all these years anyways, to properly figure out whether my thyroid problems were due to structural problems in thyroid/antibodies/hashimotos or have the problems been in my adrenal gland. If only for my brother and mother. Thing is that either i can support my thyroid/adrenal gland with just supplements or i have to be on thyroid or cortisol treatment for the rest of my life, regardless the success in my PFS recovery.

Well you take T3 so you make less T4, so none of your T4 will be turned into RT3. So by you taking T4, you are basically making more RT3. Read this… it will give you more info then i can give you… not long, will tell you what you need to know regardign RT3:

medical-library.net/reverse_t3_dominance_syndrome.html

and what JN did was increase his cortisol, that was why he was making too much RT3. his low cortisol was causing his body to turn T4 into RT3. so he had to do T3 treatment to get rid of the RT3 and increase cortisol so his T4 wouldn’t turn into RT3 in the future. then when he got them straight… he weaned off them and his normal thyroid and adrenal glands picked up the slack to what he was dosing.

i bought the stop the thyroid madness book which made me learn all this… they put it in easy to learn wording and repeat it a lot through the book… thats how i get it. its only 20 bux online at their website.

You are not a doctor Bryce, please stop making claims and diagnoses which are impossible to prove over the Internet, especially as they pertain to someone else’s situation other than your own. This is all simply conjecture. It would be appreciated if you rephrase such comments in a more truthful manner, such as “PERHAPS (and I am hypothesizing here), JN…”.

None of us have the ability to look inside our bodies and know exactly WTF is going on, to post like we do and claim to have the answers to someone else’s situation is to show one’s ignorance of the complexity of this problem, not to mention nobody can remotely diagnose via text or is even qualified to do so.

Don’t take that the wrong way, it’s more of a reality check than anything. Additionally, posting comments such as the above without any scientific studies to back up statements that prove these things actually occur, simply makes it all personal opinion. I’m all for discussion but if you are claiming to know what happened to someone else, please at least provide peer-reviewed studies to support your views.

I am on this drug at the moment(prednisone) and i feel nuked, its for crohns.
Hopefully i feel improvements when my coarse is finished.