Amino Acid For neurological symptoms


#222

Day 2 of Sulforaphane. No change from yesterday’s dose. It’s a thick green gooey stuff that tastes weird at best and I have to use a spoon to take it. So no drops. I’ll increase by 1/4 tsp a day and see what happens.

So yesterday I must have taken 40 mg and today I’m at 100 mg. Tomorrow I’ll take 150 mg and in two days I’ll be at the suggested dose of 200 mg. The dosage for mice was 10 mg per kg and it was injected or mixed with DMSO to get in. So I would have to take way more than that to get a drastic effect. (or mix it with DMSO and bathe in it)

I guess I could go up to 600 mg taken orally if I don’t get any effects at lower dose. It will possibly be destroyed by the stomach’s enzymes so who knows if this will do anything ?

I’m 60 kg (down from 75 before the diet) so at 10 mg per kilo that would be 600mg. That’s 3 tsp of the stuff I bought. I could mix that in 3 tsp of DMSO and rub that all over my body (of course, I would start with smaller dose. I’m just comparing myself to a lab mouse receiving the same amount).

This is not practical and if the effect is only temporary, I guess it will just be for experimentation purposes.

Let’s see if I get results from oral doses first. The best would be to get results by oral intake at 200 mg. This could be feasible, I have enough supply for 3 months at that dose.

Update: I’m shifting in mood already. For one thing, I’m taking Horny Goat Weed, 500 mg, and I took 2 drops of Pine Pollen in DMSO rubbed on my forearms (plus 12 gr of Creatine). I got a testosterone rush which is making me more aggressive and irritable. So I did some training to let some steam off.

Then it’s 6:30pm and I’m feeling tired. This is kind of a first since I’m on the ketogenic diet. I would normally feel full of energy all the time until I take my sleeping pills, and only half an hour later they would knock me down and I would sleep. So maybe it’s only wishful thinking, but it could be the overlap of some ALLO on top of the Benzodiazepine I’m taking at night. They have a long half life so they are still acting on my GABA receptors and ALLO would also if there was some.

Too early to tell. But if I sleep better today and have problems waking up tomorrow, I will have to assume that I should start decreasing the sleeping pills.


#223

Day 3 of Sulforaphane experiment, Day 104 of Amino Acid experiment.

I slept better 8.5/10 and woke up quite drowsy. I will cut down Hydroxyzine from 7.5 mg (3/4 of pill) to 5 mg (1/2 pill). I still wake up around 4am but go straight back to sleep. The period between 4 and 6:30am had less dreams, less turning and tossing, and more deep sleep (or what felt like it)
Honestly, considering this is my last effect from pfs, I could live with that the rest of my life. But I’ll continue my efforts until I’m 100% and I don’t need so many supplements. I’ll keep the diet and exercise though, it’s very nice to be in a 28 yo body when I’m 51 (still no gray hair or wrinkles, people give me 35 yo). I’m still exploring what I can do. I feel like Captain America after being given the super soldier serum !

I’ll keep Clonazepam at same level for now, there is withdrawal symptom and last time I tried to lower by 15% I had a bad night.

Yesterday evening, my armpits smelled bad. It’s the first time in 9 months I smell like a man. I think Sulforaphane is having and effect but it’s too early to be sure.

Today, to avoid a testosterone rush, I will not use Pine Pollen DMSO. Only Horny Goat Weed, of which I’ll take 1000 mg.

I’ll also take 150 mg of Sulforaphane, 3 mg of Boron and 12 gr. of Creatine

Let’s see what happens.

Update: I have been having brain fog in the afternoon in the few last weeks. I compensated by taking 500 mg of Tyrosine like one would take an aspirin (by the way a small steak has 2000 mg of Tyrosine. I’m just pointing out how natural my approach is).
Today, I was highly motivated at doing my work, very focused and didn’t have to take Tyrosine at all. I have a strange feeling of calm joy I haven’t felt for a while. I have been so dreadfully serious in the past few years, it looks like I lost most of my joy of living (joie de vivre in French !)
It could all be psychosomatic (like a placebo effect) but for one thing, I had sex with my wife this morning and sex drive was still strong in the afternoon. So considering I’m having no ill effects from Sulforaphane (and maybe no effects at all, it may only be my imagination) I will take 50mg before sleep. That will bring me to 200 mg for today, which is the recommended dose and still 3 times less than the poor mice in the experiment.
It’s breaking my rules of prudence but since I began taking that stuff I’ve only been feeling good (Aside from the testosterone boost from combining Pine Pollen and Horny Goat Weed yesterday). Anyway, I want to see if taking it before sleep makes me sleep better.

I’ll post tomorrow.


#224

any idea if sulfuro could be aiding in decreasing the brain fog?

thats what some users reported on other platforms


#225

I suspect the increase in T from taking those supplements might be adding to the body odor, etc… It would have been interesting if you had gotten blood work done to see where your T levels were before you started this.


#226

I didn’t do any blood tests except the one right after crashing (everything was in range except very low vitamin D and elevated Cortisol)

However, I’m very sensitive to how I feel and I can actually tell my testosterone has been boosted by the herbs, considering my sex drive did. But it’s not the first time, I even took TRT at the beginning, and I never had smelly armpits. It’s something else, some metabolite of testosterone that does that in my opinion.

Although it’s too early to say, Sulforaphane may be what reduced brain fog and armpit smell. Otherwise, it’s quite a coincidence both happens 2 days after starting taking it. I’ll know more in the following days (weeks) if brain fog doesn’t come back. And I won’t put deodorant to see if the effect (of stinking) in persistent.


#227

Day 4 of Sulforaphane and day 105 of amino acid experiment.

I took an extra an extra 50 mg Sulforaphane before going to sleep and sleep quality has decreased (7.5/10). I woke up after 4-6 hours , I didn’t check the time, and kept waking up and dreaming after that. Weird thing, I continued on the same dream after every time I woke up to turned around and felt asleep the next 10 second. I didn’t have to bring my kids to school today and ended up sleeping 11 hours without realizing it. Looks like the sleeping pills are dragging on.

I did put an alarm to sleep no more than 8 hours, but it didn’t ring or I didn’t hear it.

Anyway, I won’t take Sulforaphane before sleep. I’ll take half (100mg) in the morning and half (100 mg) in the afternoon, same with Horny Goat Weed (500 mg) or whatever herb I’m on for the week, when it’s on a day I take it twice.

Update: I don’t have brain fog but I’m rather hyperactive and somewhat stressed (but not in a bad way. More like stimulated). Is it the Sulforaphane, the Horny Goat Weed, the 3 mcg of Boron or the Creatine ? I don’t know. That’s what happens when you start 4 things at the same time.

I can’t say I’m complaining, I’ve got tons of work and I’m chewing through it at a fast pace.

This is how I used to be before fin, when I started my third business in Canada. I would work non stop 110 hours a week, eating and showering in between and sleeping only 7 hours. I became successful in a few years.
I remember asking myself 3 years ago where did that fire go ? Would I ever be able to be like that again ?
At that time I didn’t know I was being affected by fin, but I knew something was poisoning me and I was getting worst each year.

Maybe it’s not the 4 new supplements that makes me hyper. I mean, I was hyper as a child (back in the 70’s, they didn’t drug us. They let us develop our potential). It looks to me like my motivation has come back, my drive, the way it was before I started taking this shit (fin). I would only stop working when there was no more work to be done, and when you own a business, that can take a long time.

I’m happy ! This is great ! The sky’s the limit again !


#228

Hello Ozeph, what part of your regimen to do you credit for ridding yourself of brain fog?

Thanks.


#229

Sulfotaphane 200 mg per day but it could be Creatine as well (12 gr. a day for 10 days then 2.5 gr a day) (or both)

Creatine boosts brain performance:

And whatever did it, it did more than that; it woke up feelings and sensation I didn’t have for the better part of the last 20 years (I took fin 20 years)


#230

Day 5 of Sulforaphane and Day 106 of Aminos experiment.

I didn’t sleep good and that’s not a surprise. After oversleeping 11 hours yesterday and being hyper all day, I knew I wasn’t going to sleep good. I especially had a hard time falling asleep, but I also woke up frequently.

This morning, I got up at 6:45 am but I could have slept a lot more.

Today, I took the Horny Goat Weed at 7am, and will not take another one later. I think that’s what makes me hyper. I’ll also take the Sulforaphane 100 mg on a full stomach right after breakfast and will take another 100 mg in the afternoon.

I doubt it’s the Boron 3 mcg or the Creatine.

But considering Sulforaphane is putting a few things back to their place, it’s also possible one of my regular amino became too much. I feel like there’s a surplus a something and I’m hyper again today. It feels like a testosterone rush but without being aggressive. Could be the GABA being overwhelmed by both benzodiazepine and ALLO (I wish)

I will stop the Horny Goat Weed for the time being and see what happens. I don’t care too much about sex anyway. What I want is my mind back and my ability to sleep.

Also after lunch, I will only take a half dose of 5-HTP, L-Dopa and Tyrosine.


#231

Do you know if Sulforaphane and Creatine could cause a PFS crash?


#232

I’m getting really bad brain fog from what I think are the broccoli sprout extract capsules, I’m not sure how much sulforaphane I’m getting from these but it’s very intense brain fog that lasts a few days. It’s happened twice now after taking a single serving of 2 capsules


#233

Damn, sorry to hear that. Maybe the brand your taking has additional ingredients?


#234

Stop it. It’s not working for you.

L-Tyrosine 500-1000 mg is good at fighting brain fog.


#235

I doubt Creatine would. But considering it raises testosterone, 5ar and brain focus, it might as well cause a crash.

Sulforaphane can definitely make you crash. It plays exactly where we got hurt. It’s a delicate intervention, like neuro-surgery and it can go bad.

a meal in a Japanese restaurant made me crash 4 months ago…


#236

Day 6 of Sulforaphane and Day 107 of Aminos experiment.

I had a demotivated day yesterday, as much as I was full on, the day before.

However, I made 3 mistakes in my regimen. In the morning, I ate carbs, I didn’t take my morning protein shakes which also contains among other Pregnenolone and DHEA, which produce Progesterone, Testosterone and Estrogen and I took my hormone balance mix (which flushes excess Estrogen) at the same time as the electrolyte mix and ended up with a diarrhea. It means I didn’t digest the lunch pills. To top it all, I didn’t take Horny Goat Weed and Pine Pollen DMSO. All in all, Only the morning pills were effective and the afternoon I got a look at my baseline, without any supplements.

No anxiety, no brain fog but also low sex drive and low motivation. Motivation so low indeed that at 6pm, I didn’t even feel like playing with my phone or watching Youtube, I just wanted to sit down on my bed and wait for bed time. Yuk. Never got that low. Maybe the day before I depleted all my Dopamine, I’ll have to experiment more to know how to balance things.

Yesterday I also took my sleeping pills at 8 pm and went to sleep at 10 pm. It made it easier to wake up at 8am. That’s almost 10 hours of sleep considering I don’y fall asleep right away, i’ll adjust down so I sleep only 8 hours. But taking the pills earlier helps waking up earlier.

So this morning, I’m taking a coffee, a protein shake with all the extras in it, Pine Pollen DMSO, Horny Goat weed (I also want to check if body odors comes back with those 2), Hormone balance mix and Sulforaphane. I’ll miss nothing and it’s all on my list. I’m now playing with my hormone balance. I think I’m solid enough that I can take it, as long as I don’t get stubborn and insist on taking things that makes me feel bad for days or weeks.

update It’s 6 pm and the day went fine. I had energy and was calm and I motivated all day. However I can see these new changes in the supplements are depleting my Dopamine faster. Yesterday evening I was very low on Dopamine. Today, in the afternoon, I felt the need to take another 175 mg of L-Dopa (half a pill). But altogether I had a fine day.


#237

Day 7 of Sulforaphane and Day 108 of amino acids experiment.

I had a bad night of sleep. 4/10. The weird thing is I was tired at bed time and went to sleep fast but I just kept waking up and falling asleep lightly, dreaming all the time. The dreaming zombie state as I call it. I usually feel not rested after a night like that.

I made five changes in my regimen:

I’m taking Creatine. It could be it but it’s said to be to be non-stimulant and can be taken at any time during the day. (for non-pfs people anyway). It boosts testosterone and androgen, but only if you exercise which I haven’t done that much. I’m in the load up period and still suppose to load up for 3 days but I’ll just take the maintenance dose for now until I can fix my sleep.

I’m taking 4.5 mcg of Boron if adding my multivitamin. I doubt this makes a difference. The upper limit is 20 mcg. 10 mcg is used to boost testosterone.

I’m taking Horny Goat Weed once in the morning. Could be that, but it’s supposed to affect testosterone and sex drive, not sleep. Plus I stopped One day and sleep was bad anyway.

Sulforaphane. Yesterday I took around 300 mg. It did make me feel calm yet confident and motivated during the day, and I was sleepy before bed. But I slept bad while just a week ago, before any changes in my regimen, I was saying sleep was getting better. (8.5 or 9/10) Today I will reduce to less than 100mg and see what happens.

Sleep patterns: The 2 months school vacation just started in Thailand. My sleep patterns are all upset. I go to sleep at the same time but woke up at 8 instead of 6:30. So instead of 8 hours, I get 9 and half and that, by itself, has always caused bad nights on the next night.

So I’ll fix my night pattern, that’s the best educated guess I can take as oversleeping has always resulted in bad sleep the next night. I’ll cut down Sulforaphane to 100mg until I get better sleep. If after fixing my sleep patterns I still can’t sleep good, I’ll have to cut Sulforaphane.


#238

Day 8 of Sulfotaphane and Day 109 of Amino Acids experiment.

Sleep restored. 9/10. I barely woke up, just turned around in half sleep a few times and went back to sleep. I don’t even remember any dreams.

So I took my usual regimen, at this point I’m quite serious about the ketogenic diet, I’ve augmented saturated fat and diminished protein although I probably still take a little too much (like 10-16% too much).
However, I had a few carbs at dinner (like 1/4 potato and 1 tps of flour). Maybe that helped. I don’t mind a few carbs at targeted times if it helps.

Yesterday, of all 4 new supplements, I took:

Creatine 2.5 gr
4.5 gr Boron
Horny Goat Weed 500 mg (plus 2 drops of Pine Pollen DMSO) so I got body odors (that’s good I figure)
Sulforaphane 50 mg in the morning.

And I re-established proper sleep patterns. I counted 8 hours plus 15 minutes so I can fall asleep and woke up on time.

I’m going to try and maintain that for a while and then see if increasing Sulforaphane alone (no other changes) is beneficial or not.


#239

Recent day recapitulation.

A lot has been going on since I took Sulforaphane and the other supplements. So I think a recapitulation is in order.

First : This morning I took only 500 mg of Horny Goat Weed without the Pine Pollen DMSO and I’ve got my body odors back, so it’s Horny Goat that does this. Anything that went away with pfs and then comes back is a good sign. I will integrate Horny Goat weed into my regimen permanently, although I may alternate or take breaks to avoid tolerance.

Second : On Day 4 I took quite a lot of Sulforaphane and had a hyper-active day where I felt more motivated than I did in the last 10 years. I was calm, super confident and in a good mood, plus all brain fog was gone. That all points out at a high usage of Dopamine, Serotonin and Tyrosine, which can mutually deplete each others.

The following days I’ve been demotivated, began feeling depressed, had less confidence and slept bad. I didn’t notice any excessive brain fog. It seems to me the Sulforaphane did have an effect on something that went missing with pfs (hence the disappearance of brain fog and the feeling of being calm despite the other bad effects) but altered the balance of my other neurotransmitters.

Being demotivated point out at depleted (or lower) Dopamine. Being depressed and lacking confidence points out at depleted (or lower) Serotonin. Sleeping bad may be an interaction between ALLO, which regulates the GABA (A) receptors, and the intake of a benzodiazepine (clonazepam) which also acts on GABA (A)

Now I’m not sure about the sleeping part. But I’m pretty sure about Serotonin and Dopamine being low. I have experienced enough with those to feel the difference. This can happens when burning lots of Tyrosine, which would also deplete Serotonin and Dopamine. It would, in my opinion, also deplete Phenylalanine.

So today, I will try low doses of Phenylalanine and a low dose of St-John’s Worth, which is a unique Non- Selective All Neurotransmitters Re-uptake Inhibitor. I know it’s dangerous when taken with 5 HTP, but I will feel it and stop that herb if Serotonin is high.

Update: it’s 7:30pm and I had as normal a day as could be. In the last few months, I could control stress and anxiety with serotonin, which provides calm confidence but there was always this feeling of tension or stress inside. However I now feel more calm and relax inside without the rush of serotonin. I don’t know if it will last, but today I felt like all my neurotransmitters were more in balance. I felt normal, motivated, full of energy, focused etc…

I will monitor my feelings carefully and make sure I don’t overdose or deplete any neurotransmitters.


#240

In my opinion, you fixed your homeostasis. A normal person does not need all this stuff to work … I know people who eat badly and are much better off than I do on a controlled diet. I believe that what works for you is just a placebo effect.


#242

You have the right to have your opinion. I agree a normal person does not need all this stuff. I’m sick, I’m not a normal person. I disagree it’s just a placebo effect. If you read this whole thread, you would see I had many different negative effects as well as overwhelmingly positive ones that were not sustainable so it can’t be placebo.
I believe what bothers you is I’m taking 5-HTP and you consider this to be a poison whereas it is only one if you combine it with a SSRI, alcohol or certain herbs like St-John’s Worth. This is what got you sick. Now I’m combining 5-HTP with a low dose of St-John’s Worth and monitoring the situation carefully (I’m ready to stop the herb as soon as I feel I have too much serotonin)
Do you still think 5-HTP only gives a placebo effect or it actually does something ?
That’s my opinion and just like you, I’m allowed to have one.