Dear members,
We are working to conduct a Genome-wide association study(GWAS) across patient groups based on the SNP data provided with the DTC genetic testing service 23andme.
We will be using high powered software and computing resources to perform a research project for the community. We are hoping to identify associated SNPs, and possibly observe similarities between those suffering the respective conditions at the genomic level. It is hoped that this information will help us and our scientific contacts better understand possible underlying genetic susceptibilities that could contribute to development of these syndromes. This is in contrast to the majority of people therapeutically using these substances who do not suffer persistent and devastating health problems following cessation. If statistical analysis of symptomatic vs control data sets reveals interesting findings, we will endeavour to work with one or more scientists to help us deepen our investigation and publish the results in a peer reviewed journal.
UPDATE Jan 19, 2020: Acceptance of new submissions is closed until further notice and basic analysis on the current data set has begun. See the following post in this topic for more details:
To achieve this, we need your help. If you already have taken a 23andMe test in the past, please click here for instructions on how to obtain your raw data. If you have not taken a 23andme test and would like to contribute your personal data to our project, please consider ordering a 23andme at-home saliva sample kit from their website. The cheaper ancestry option is sufficient as we require the raw data file, which is identical with either product offered.
Once you have downloaded and extracted the raw text file, please rename the file before submitting including your forum username and substance taken in the following way:
ForumUsername_substance_23andme.txt
Examples would be as follows:
user1_finasteride_23andme.txt
user2_accutane_23andme.txt
user3_ssri_23andme.txt
user4_sawpalmetto_23andme.txt
user5_dutasteride_23andme.txt
user6_lupron_23andme.txt
This will help us track which users have submitted data and their respective conditions.
Once your file is named appropriately, please submit your raw data file (once) via the following link. By submitting your data, you consent to the use of the data for the aforementioned purposes.
(insert dropbox link here)
Thank you for your participation
– propeciahelp staff