My main query is that the funding required seems a lot higher than what was stated in previous posts, is this the case? Or perhaps I’m confusing it with another study. I’m referring to the one which states in awors post will be left aside for the time being.
Awor will need to clarify that, I do not know myself.
Regardless, scientific research costs a lot of money, so be prepared for that.
The discussion posts in this thread were split from the 2012 Scientific Research Initiatives into the Post-Finasteride Syndrome thread found here:
This thread is for continued discussion of the Scientific Research Initiatives updates.
I read through Awors complete theory write up, 28 pages. The theory is very plausible as it can possibly explain all the PFS side effects especially the mental ones that have been largely ignored and are in my opinion the worst by far.
where can i read the theory??
Please describe your mental side effects.
Can the study give us potential treatment to this disease?
Here is a diagram that shows alot of the potential players in AR signalling. Not everything is here like LSD1, jmjd2c, ARA70 etc… But it gives you an idea where we are looking.
Interesting… Assuming the correct gene is identified as being where thr problem resides what sort of treatment options can we start looking at? Or are we going to have develop am entirely new one from the ground up?
If we know where the problem is we can target it more accordingly. There are already alot of things out there which affect different parts differently. Otherwise we can potentially create work around solutions. It seems to me we need to know WHERE the issue is and then the HOW it has been affected to make progress.
The way i see it is we now have a plan and are no longer swaying in the wind. A few years ago we have no hope of finding out. Now we do. We know where to look.
Yes that’s what I’ve been telling people … Very good news overall. Hopefully we can all look forward to rebuilding our lives soon enough. If ya need anymore DNA samples let me know, I got hit by pfs pretty hard so I’m sure mine would work well for testing.
I’m sorry but this is wrong.
“Binding of Testosterone or 5alpha-Dihydrotestosterone to Androgen receptor induces its dimerization, which is needed for binding to Androgen receptor 's cognate response element and recruitment of co-regulators, such as transcriptional co-activator protein E1A binding protein p300”
Because of Merck we all know that Dihydrotestosterone does not have any essential physiological role in the adult male. The incredible, fully-competent FDA doctors can corroborate.
Yes, please do some research 19. You’re beginning to sound like a crazy man. DHT is nonessential and thus a path we shouldn’t be looking into. I’m much better off because I base everything I know off of Merck’s published studies. Therefore, logically this is all in our heads. And since typing that I’m already feeling better and my boys have magically grown back to size. Apparently, our imaginations can really make some pretty potent side effects.
Just adding to your sarcasm, Second
I don’t think you understand what I wrote. It infers that the problem is to do with androgen signalling not with testosterone or DHT directly.
none of you are scientists.
i’m just illustrating what sort of thing is being looked at by research scientists.
And on a note of celebration as of yesterday I am now a doctor. Its been tough but i got there!
SA and domino were just being sarcastic.
Congratz on your MD! NOW get out there convince the rest of the retards in the medical community that this is real.
What sort of Doctor - GP?
thanks mate!
No i’ve just qualified so completed medical school with a MbChb (UK MD equivalent). I do two years as a junior doctor in UK before specialty training. This includes being a GP for 4 months but everything i do is monitored by seniors etc…