What can you do to bring down Prolactin

[Bradwaggoner]

I’m one of those slightly high prolactin folks, just to document. 15.5ng/mL Range: 4.0-15.2ng/mL

[heyder]

I have high out of range Prolactin as well.

[visionquest99]

@heyder

I have high out of range Prolactin as well.

Have you guys taken Dostinex? If not, why not? I just read some positive reviews on this med.

[Mens_Rea]

Dostinex/Cabergoline (same thing) is the best

Take 0.25mg twice a week for 2 weeks and that should be enough.

[bluecloud87]

I am definitely going to try dostinex next. Just gotta find the cheapest supply in the UK.

[wlan]

I have taken 0.5 mg Dostinex 2 nights ago. Today, when i saw a hot woman on the street, I was excited like i did when i was a teenager. Your heart beats like crazy. I will continue taking Dostinex for 2 weeks. My regimen is: taking 0.5 mg Dostinex, 2 times a week, before sleep. I will inform you guys about its effects.

[toadstool]

from what Ive read its very potent stuff… be careful.

[bluecloud87]

Anyone else on cabergoline? I am thinking of buying Cabgolin (same thing) because it is cheap for me to get here in the UK!

[191]

I’ve found out I have high prolactin too. In the past it has been fine but it has gone up over the last few months first to 600 now to 771. The upper end of the range is 450. Can’t remember the units of the top of my head.

Thinking about starting quinagolide to get it down. Its a bit more expensive than cabergoline but it is a non-ergot derivative and therefore is a little bit safer.

I would also recommend abstaining from masturbation for a while as orgasm gives a rapid increase in prolactin. It is one of the things responsible for the refractory period after sex.

[191]

sciencedirect.com/science?_ob=ArticleURL&_udi=B6T3G-47STM4V-30&_user=10&_coverDate=09%2F30%2F1976&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1750756106&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=c1c8d4c9cc667328d14698ad546b58a7&searchtype=a

Effect of prolactin on vitamin D metabolism

The effect of ovine prolactin on the renal 25-hydroxycholecalciferol-1-hydroxylase was studied in the chick. Prolactin was found to increase the activity of this enzyme in both long-term and short-term experiments. In the long term, 7 days treatment with prolactin caused a marked stimulation of the 1-hydroxylase activity, however this effect was only seen when the enzyme was assayed 2–3 hours after the final injection of prolactin. A single subcutaneous injection of prolactin was also effective in increasing the 1-hydroxylase activity, this effect was maximal at one hour and had largely disappeared 3 hours after prolactin administration.

So increased prolactin can increase the rate of vitamin D metabolism.

[visionquest99]

Anyone heard of this new supplement “Cabergolean”?

Here’s a vid about it: Link

Here’s a write-up: Link

I cant purchase the real stuff - dostinex - (no one ships to Cda) unfortunately.

Chicago — June 1st, 2011 — Nutrigenomics Research Company has announced the release of its innovative, new supplement- Cabergolean.

Cabergolean is the most powerful HGH Booster, Prolactin Inhibitor, and Nutraceutical Nootropic ever to be sold as a nutritional supplement. Cabergolean also acts as a powerful Nitric Oxide (NO) Releaser, and Sleep Enhancer. Cabergolean naturally increases endogenous production of HGH through a clinically proven increase in GHRH (Growth Hormone Releasing Hormone) and through the suppression of GHIH (Growth Hormone Inhibiting Hormone or Somatostatin).

Cabergolean is a clinically proven, proprietary formula that you will not find in any other HGH Booster.

Here is what the science behind Cabergolean clearly communicates:

Cabergolean improves memory and the ability to focus

Cabergolean improves memory and the ability to focus by increasing the amount of the neurotransmitter Acetylcholine and Dopamine. Acetylcholine is involved with synaptic plasticity, specifically in learning, short-term memory and the ability to sustain attention and focus. Studies involving Dopamine’s effects on cognitive performance clearly illustrate the link between enhanced cognitive performance and Dopamine production(28,29).

Huperzine A, N-Acetyl-L-Carnitine, Pantothenic Acid, and dimethylethanolamine (DMAE) either facilitate the release and synthesis of Acetylcholine or inhibit Acetylcholinesterase (an enzyme that degrades Acetylcholine)(4,5,15).

Cabergolean also employs the use of N-Acetyl-L-Carnitine. N-Acetyl-L-Carnitine has been shown to improve memory, increase energy and allow the energy-producing organelles in our cells (mitochondria) to work more effectively by protecting them from free radicals(20,21). Cabergolean also employs NADH as a scavenger of free radicals. NADH is also referred to as Coenzyme 1. NADH (or Coenzyme 1) executes the scavenging of free radicals better than any other biological substance known to the body.

Cabergolean improves HGH output

Cabergolean significantly improves growth hormone production, and it does so in a two-fold process. The this two-fold process is critical! You can increase the production of growth hormone with many supplements; however, if Somatostatin is present than there will be no release or “pulse” of HGH. Somatostatin acts as a gate for your endocrine system so that HGH is not released from your Anterior Pituitary Gland.

1. Cabergolean produces a significant rise in plasma growth hormone via the production of L-Dopa which is found in Mucuna Pruriens and synthesized from the amino acid N-Acetyl-L-Tyrosine(3,6,7,33) and the coenzyme beta-nicotinamide adeninedinucleotide (NADH)(26). As a matter of fact, one University study** showed that 90 minutes after oral administration of 500mg L-Dopa, plasma GH levels increased from less than 1 ng/ml to 21.7 +/- 4.7 ng/ml in “most normal subjects”(34) (meaning those individuals without endocrine disease of any sort). That is over a 2000% increase in plasma GH.

**2 servings are required to replicate the efficacy of the referenced study.

Both Somatostatin and GHRH (Growth Hormone Releasing Hormone) are released from the Hypothalamus. Once the HGH is synthesized by the Pituitary Gland it goes into a “waiting area” or pool to be released.

Somatostatin inhibits the “flood gates” from being opened and a subsequent release of GHRH to the Pituitary Gland. Somatostatin also inhibits the “flood gates” from being opened and a subsequent release of HGH by the Pituitary Gland. So the key here is to “flood the pool” via the production of L-Dopa, which stimulates the Hypothalamus to produce GHRH and deliver it to the Pituitary Gland, and then to open the “flood gates”, by inhibiting Somatostatin, via the production of Acetylcholine.

Prolactin is a hormone produced by the Anterior Pituitary Gland primarily associated with lactation and plays a vital role in breast development during pregnancy. Now if you are a pregnant female or you plan on becoming a pregnant female in the near future, then Cabergolean is NOT for you; however, if you are a casual fitness enthusiast or any type of athlete then excess Prolactin may not be for you! Prolactin also acts as an inhibitor of Gonadotropin Hormone Releasing Hormone (GnRH) neurons, which indirectly stimulates the production of LH (Luteinizing Hormone) and Testosterone.

Research communicates that lowering clinically high Prolactin levels can improve libido significantly! Eliminate or reduce the signs of gynecomastia! Improve sperm motility! And increase Testosterone(9,30)! The decrease in Prolactin levels come via the increase in Dopamine from the compounds Mucuna Pruriens Extract, N-Acetyl-L-Tyrosine, and NADH (beta-nicotinamide adeninedinucleotid).

[toadstool]

Interesting… Right in my home town… perhaps Ill pick some up… Suppose to be way more potent then L-argintine, and that stuff really gives me a boost in my workouts as it is…

[Dubya_B]

Cabergoline is not a new drug by any means. Been around since 85’.

I think some members here have had some, although minimal, benefits from taking it. There are several threads where it has been discussed.

[toadstool]

@Dubya_B

Cabergoline is not a new drug by any means. Been around since 85’.

I think some members here have had some, although minimal, benefits from taking it. There are several threads where it has been discussed.

You clearly didnt read…

[visionquest99]

@Mew

Answers to your question have already been given above. You may also consider Mucuna Pruriens, a natural supplement containing L-DOPA (often given to Parkinson’s patients). Be aware that this can be very powerful and have side effects depending on dosage.

Sorry for the bump. Did anyone give Mucuna Pruriens a go?

[Rmoney96]

This is what I’m talking about sir

[Cooper]

My Prolactin is 32. It was 12 this summer. The hell is going on.

[BibFortuna]

What are the reference ranges? Did it go from below average to average? Or maybe average to above average?

[Cobra_Red]

My prolactin is high and above the range, I’m wondering if those medications Dostinex or Cabergolean were safe and if they helped?

[hopeless94]

Vitamin B6 is a natrual prolactin inhibitor, try that first…