In 2012 my doc prescribed me borage seed oil to treat seborrheic and atopic dermatitis.
This supplement didn’t have particularly effect so he prescribed me protopic 0,1% (tacrolimus).
Protopic worked greatly but after a while I developed sexual side effect like memory problems, completely impotence and zero sex drive.
At the time I attributed side effects to protopic but today I found out the prescription and I noticed that I started to use protopic about two weeks after stopped borage seed oil.
Borage seed oil contains high amounts of gamma-linolenic acid (GLA), a strong 5-alpha reductase inhibitor.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1132824/pdf/biochemj00131-0210.pdf