One thing I would like to say about this: PFS and cancer are vastly different. One will literally grow malignant tumours that kill you. That’s one of the main reasons cancer is so fucking hard to cure/treat - because often by the time it’s discovered, it’s far too late.
Yes, I understand that PFS is in some cases, progressive. But after the initial crash, the disease does appear to stabilise in many.
And thank you, @loops, you are absolutely right. The equation is simple. The more money we raise, and the faster we raise it, the sooner brilliant scientists can do their jobs and provide us answers.