Has anyone tried finasteride again after they crashed? I’m just curious if our bodies silenced the AR receptors because of DHT flooding back into the system then if we totally depleted DHT levels again wouldn’t the body resensitise the AR so that it could activate DHT. It’s seems counterintuitive and a scary prospect but I’m wondering theortically if this would work and if anyone tried?
I got it from a single dose and yes this would be extremely risky and that is why I want to know if anyone tried it.
I believe if we try to completely deplete DHT levels with duasteride then the body would have no choice but to unsilence the androgen receptors because DHT has reached a critical level. I know that my body is still producing DHT otherwise I wouldn’t have a beard but I know the AR receptors aren’t utilising the available DHT in all tissues.
But completely depleting DHT is what caused this in the first place! In theory what could work would be increasing DHT to downregulate receptors.
dont recommend it, some people have seriously messed themselves up 100x more taking fin again as well as other anti androgens after they had PFS
first they got better, then they crashed and got so much worse that many ended it
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People have tried this method and it doesn’t work an increase in DHT doesn’t seem to reawaken the AR receptors. We still have DHT flowing inside us which can be verified by bloods most of us with normal levels- the issue is with the receptor sites being silenced.
If we had high androgens to begin with we would have a higher susceptability to PFS and by us taking finasteride it blocked DHT being converted so our bodies silienced those receptors in response to resurging DHT which caused the infamous crash. I think a hugh number of receptors have been switched off if this is true then blocking DHT would theortically unsilence those receptors as the body upregulates the receptors in response to low levels of DHT.
So there’s been people who tried finasteride again while having PFS? I wouldn’t say theres many people that retried it after getting hit with PFS out of sheer fear and I probably wouldn’t either as my condition is dire.
just about everyone who tried finasteride or other anti androgens while having PFS, got screwed up again.
thats why very few try fin while having PFS
because no one wants to get 1000x worse.
no one knows what its like to be way worse, all we know is that if we take fin again we might know
I do, I’m basically disabled it couldn’t get any worse.
I think very few if anyone has tried finasteride again after they crashed because PFS scared the living daylights out of them. If you put your hand in a fire you def wouldn’t do it again and for that reason I can’t imagine why anyone would try it again.
My theory is if you brought DHT right down surely the body would resensitise those receptors in response to low levels.
If Gene’s are silenced to AR it’s not gonna do anything because they’re offline and basically dead in certain tissues…But as other’s have said Do NOT take it again for any reason…Moving dht levels up and down won’t un silence genes if that is even what is wrong with us…In any case it is not worth the risks it might actually cause other genes to up or down regulate??
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There’s been a few. Some got worse, others WAY worse, some got temporarily better, I don’t think anyone actually got cured.
Even I wouldn’t do it unless it started randomly fixing 90% of sufferers.
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I don’t think anyone on this forum has tried lowering DHT. We need to think outside the box if our genes switched off the androgen receptors due to an overflow of DHT rushing back into our systems then surely lowering it would signal the body to resensitive the receptors in response to low levels.
Is there anyone on this site that you know has tried it?
In a sort of way I have unknowingly!. I took fin on and off for 20 years. I had lots of issues with numerous symptoms appearing weeks after I stopped. I never tied these into finasteride as have rheumatoid arthritis, visits to doctors / consultants drew a blank. I’d generally have 9 month on and 3 off. I now have every symptom on the list as well as a few others. I believe I’ve had a number of crashes and have had no improvement only a worsening of symptoms. It would be like putting a gun to your head.
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I took finasteride again after developing pfs in 2012. Took it for another 9ish months in 2017 and all it did was give me mental symptoms this time around. Thankfully they subsided somewhat but my sexual symptoms remained the same and thankfully didn’t get worse
Interesting thank you for your clarity on the matter
In your case you took it for 20 years so I’d definitely expect some adverse sides for someone on it as long as you. Tell me something is your face still oily and has your hair loss continued I ask this because this would be a strong indication your DHT is online. In my regards I’m a one pill catastrophy so once I took the pill DHT instantly shut offline permanently in your case you took the drugs for 2 decades inhibiting the drug for that long is bound to come with health conditions. There must be a mechanism to get DHT working again and this seems like the only viable solution to turn those AR’s back on.
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The question is after you got PFS why did you risk it again.
My skin is as dry as sticks that started 6 years ago and has not recovered. I’ve lost hair coverage across the top and back. In answer I did not know I had PFS until two years ago. My symptoms were never tied into the drug. When I first took it the only side mentioned was a temp loss of libido nothing else so I never looked at this as the cause. The rheumatoid autoimmune disease was seen as the potential issue I was never convinced. As more and more symptoms appeared the doctors ran out of ideas then I was made to feel like I was imagining it all as bloods always came back normal. I stumbled across this site under 2 years ago and it all fell in to place. I immediately stopped taking propecia. If anything I’ve got a lot worse since.which I didn’t think was possible. The damage caused is long-term and in my opinion for me irreversible.
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Unless we get your androgen receptors back online that’s the solution to all our problems.
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Because at that point all I had was sexual symptoms and I was curious like you to see if it might help. Also i was losing hair again and I thought what could I lose, my symptoms aren’t getting better anyway. But it can always get worse
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