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Something of interest (if not already posted)
mendeley.com/research/17-betaestradiol-induced-prostatitis-rat-autoimmune-disease/
'17 beta-estradiol induced prostatitis in the rat is an autoimmune disease'
Abstract
PURPOSE: Studies suggest that alteration in steroid hormone levels may be one of the factors causing nonbacterial prostatitis (NBP) in rats. We hypothesized that hormonally induced prostatitis in the rat may be an autoimmune disease. Studies were carried out to prove this hypothesis. MATERIALS AND METHODS: We injected 17 beta-estradiol (E2; 250 micrograms/kg. subcutaneously) or vehicle into 1-year-old male rats for 30 days, and isolated and cultured the splenocytes in the presence of con-A (Experiment 1). Approximately 10(7) splenocytes were adoptively transferred into young naive syngeneic rats. To find out whether or not the inflammation is mediated by T-lymphocytes, a pure population of T-lymphocytes from E2-treated 3-month-old rats was injected into young naive syngeneic rats (Experiment 2). To rule out the possibility that the inflammation was due to con-A itself, we cross-linked some T-cells with anti-CD3 antibody before adoptive transfer (Experiment 2). RESULTS: The recipients of splenocytes from E2-treated animals presented evidence of inflammation in terms of lymphocytic infiltration and presence of degranulated mast cells. Furthermore, we observed in these animals an increase in histamine-releasing peptide (HRP) levels, an indication of plasma extravasation. The T-cells stimulated by anti-CD3 antibody produced a similar degree of inflammation, thereby ruling out the possibility that the inflammation was due to con-A. The results also indicated that the immune response to antigen(s) is not dependent on the age of the animal but is dependent on a population of CD3+ T-cells. CONCLUSION: Our results demonstrate that hormonal imbalance and autoimmunity in male rats produce the symptoms of nonbacterial prostatitis.
I took them because of a history of IBS (although diet changes managed that)ā¦and previous antibiotic usage (acne) and suspected candida. Doc wanted to clean me out. Prostatitis wasnāt remotely on the radar at that point in time. And the antibiotics were taken for only 10 days.
Iām taking nothing now.
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I took the same but with nexium (acid blocker) instead of the metro. I was taking it for gut bacteria (h-pylori). As I mentioned beforeā¦I felt a little noticeable improvement/relief in my Fin sides while on these meds. That clarithormycin is the killer, fucked me up that week badly.
My hormonal status is post-andropausal impotent 30-something male. 
Iām awaiting some fresh baselines of the full array of hormones (full thyroid panel, 3adiolG, etc) away from all medications from this weekās blood draws.
These labs are from 1 month after quitting armour thyroid, 2 months after quitting a brief flirtation with Clomid, and Tongkat Ali usage.
5-10-11 labs(I didnāt get ranges from this particular doc, but I believe they are standard ranges)
FSH: 6.1
LH: 6.1
TSH: 1.0
Free T4: 1.2
TESTOSTERONE: 540
SHBG: 42
CalcFT: 90
I was also given Omeprazole (Prilosec) and Pepto to calm the stomach, but I was still messed up, inside out, running to the bathroom all day, gurgles in the stomach, felt weak, feverish and anemic. I hate even thinking about it. This was a proactive therapy based on history, we had no tests confirming anything.
What did he get banned for?
For having an idea?
That is quite possibly correct?
Ppppfffffffffffffffffff.
you can judge yourself from his posts, however i will say he did lack really any scientific proof at that time, just claimed to go to med school.
UK20
If I was you, I wait to see if the treatment works out for āsolonjk, gefinauser, noniman, blaseā first.
i.e. wait for feedback from all of these members first before going to Greece and spending 5000 EUROS that you donāt have.
In the meantime, you have free health care on the UK, so if i was you, iād get referred to a urologist asap by your GP.
Ask your urologist for a trans rectal ultrasound of your prostrate and check for inflammation/infection/calcifications.
This seems to be the first bit of advice that solonjk is recommending in this thread.
I have noticed some improvements after therapies from Dr Georgiadis, but it is still early days.
I will know better in a few weeks as to how things are going.
There are 4 guys receiving treatment now, and i think about 5 more heading over very soon - i am hoping that in two months time we will see whether this has benefited them all.
Solonjk, when can you clarify whether you have fully recovered? surely within the next 2 months?
He was a tool constantly on the wind-up, and jumped back and forth from theory to theory.
So in summary:
Solonjk, gefinauser and noiman are being treated.
Blase has also been diagnosed by a separate doctor.
If things are reproducible then this may very well play a part in our issues. However, I would still if you have numbness issues and are based in Europe take part in Awors scientific study.
Every bit helps.
Absolutely. If anyone can participate in the studies, or anything useful towards the cause we must carry on doing so. It would be silly to put all our eggs in one basket, nobody knows whether this will indeed turn out to be āthe cureā. The fact of the matter is, if 10 guys are going out to see Georgiadis, and the treatments resolves there issues - itās pretty damn clear where the problems lie.
Until then, we just have to waitā¦
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Is is only me or this thread doesnt show up anymore in the ālatest forum postsā list (on propeciahelp.com home page) when a new post has been made, even when Iām logged in? Until yesterday everytime a new post was made in this thread, it would appear in that list (if logged in).
Could it be further precaution made by mew to hide the thread from Merks spys? I know they would most probably jump on āthe prostatitis is the cause of your troubles, not finā theory, but itās pretty certain than fin should be the trigger anyway by causing radical changes in the local immunity of the prostate.
really it is his forum and he is allowed to show what posts show up and what do not. He is not preventing you from seeing Dr G or thinking that prostatitis is the issue. Anything that leads to merck no longer producing this drug, which includes our lawsuit, is a good thing - no matter what the cause.
Nop. you are wrong his theory is not about penile numbness/insensitivity only. It is about intercellular DHT metabolism. I think by far this is the best theory which answers all of questions like
1-Many of us have above normal level total testosteron and DHT yet feel /have all symptoms of hypogonadal males. In other words despite higher than normal DHT or testosterone we are hypos. It dosenot matter how your total testerone is higher than normal naturally (in case of JN) or by means of TRT ( in case of to-robin).
Only it can describe why we have smaller balls now.
2-Many people inculding myself when applied TRT felt nothing and testosterone stayed at a higher level months after stopping TRT. My testosterone was good even after 40 days after stopping Agel.Again since it was being metabolised very slowly it kept floating in me blood.
3-It describes why some people got worse or even got gyno months after stopping fin / SP.
4- this is the only theory which covers both male and female getting affected alike at cellular level.
The prostatitis theory covers most of this PLUS A HELL OF A LOT MORE, except when it comes to your 4th point which I couldnt really give a shit about. I dont care about women who are having problems, nor hermaphrodites, nor trannys. Nor, either, do I care for people on here that are complaining about sides and putting others down when they havent even taken finasteride.
One thing I wonder about is what types of bacteria other than the āclassicā STDs can instigate a prostatitis situation?*
Would one necessarily have to be promiscuous? or just unfortunate? or immuno-compromised?
How much sexual experience do the younger PFS guys, have, for example? The 19, 20 and 21 year olds? (Feel free to speak up young impotent lads).
Could debilitating prostatitis stem from sex with a girlfriend while on her period?
Or sex with a girlfriend while experiencing an as-yet undiagnosed urinary tract infection? Or something similar?
[Size=4]*which is either cultivated BECAUSE of (or further accelerated and exacerbated by) finasterideās direct action on the prostate and/or immuno-suppressing qualities?[/size]