A pretty familiar statement,
Is 70 of your immune system in your gut?
Indeed, gut-associated lymphoid tissue (GALT) is the prominent part of mucosal-associated lymphoid tissue (MALT) and represents almost 70% of the entire immune system; moreover, about 80% of plasma cells [mainly immunoglobulin A (IgA)-bearing cells] reside in GALT.
I keep going back to Align or strain 35624 specifically because of its possible role in vitamin a metabolism.
Role of Vitamin A in the Immune System - NCBI - NIH
www.ncbi.nlm.nih.gov › pmc › articles › PMC6162863
](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162863/)
by Z Huang · 2018 · Cited by 143 · Related articles
Sep 6, 2018 — Vitamin A (VitA) is a micronutrient that is crucial for maintaining vision, promoting growth and development, and protecting epithelium and mucus integrity in the body. VitA is known as an anti-inflammation vitamin because of its critical role in enhancing immune function.
VITAMIN A, INFECTION, AND IMMUNE FUNCTION* | Annual …
Vitamin A deficiency impairs innate immunity by impeding normal regeneration of mucosal barriers damaged by infection , and by diminishing the function of neutrophils, macrophages, and natural killer cells.
So you can see a possible dual role here.
I think it could be a matter of dosage for some.
This is a statement from a top researcher in the field,
“When there is dysbiosis in the gut microbiome more RA is produced that results in a higher antimicrobial activity that can kill gut bacteria.”
So one thought would be a dysbiosis based on RA deficiency (not necessarily vitamin a deficiency but its metabolite that could be produced or promoted by select bacteria)
Meaning the dietary vitamin a is already there, its just waiting to be turned over and put to use.