Out of curiosity, has anyone else (thank you @Cbrandel) also had Prolactin out of range and if so, what happened? Did you take any course of action? What worked, what didn’t? Might not be a total cure, but can’t hurt to bring it down (naturally).
Saw my doctors again today. Here’s what’s been decided. Going to test my blood for a month. Need to see if Prolactin level was fluke. Also, will be doing these tests:
3 Alpha Androstenediol Glucuronide
DHT
Estradiol (E2) Sensitive
Vitamin D
If Prolactin remains high, I will have a Pituitary MRI on December 1st. If tumor is found, I will likely take pill. If no tumor is found (and we all agree this is most likely scenario), we will avoid pill. Not just because that could make things worse, but clearly the high Prolactin is just a stress response. Not the problem.
Any thoughts or similar experiences that could be shared would be greatly appreciated. Thank you.
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Got my Connective Tissue Disorders Panel DNA Testing Results. Only one odd thing found with: ADAMTSL4
It’s also worth noting, my samples took two weeks longer than most people. They were about ready to suggest swabbing my mouth again. Is that significant?
Anyone else discover this? Does it mean anything? Discussing with my doctors tomorrow. Thanks in advance!
Certain SNPs in ADAMTSL4 seems to affect the eyes negatively.
But the one you got isn’t linked to any specific disease in the literature that I could find.
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Thank you for sharing this. I found the eye information as well. You also literally quoted my doctor today “what I have is not linked to any specific disease (currently)”. I was told that Invitae the Company that runs the tests will reach out to me, should it ever be discovered that it is linked to any sort of disease, etc.
For the first seven months of this, the one thing that somehow stayed relatively normal was my erect penis size and strength (certainly not flaccid). Go figure. Unfortunately though, recently when it is erect, while the shaft is hard. The head is not. It’s soft, can be pushed in, pushed together, all sorts of weird ways. If you push down far enough you can feel some harder tissue (which I believe is what normally is there). My concern is the tissue in my penis head has wasted. Or, could it just be the fat that surrounded the tissue is hopefully just temporarily gone? Has this happened to you? Did it come back at anytime? Please let me know. Thank you.
P.S. I notice something sort of similar with the tip of my nose. I can grab the skin and bunch it together and feel the cartilage underneath. Whatever was in between is gone. Again, hopefully temporarily.
Super happy (and horny lol) to finally post some positive news!! First of all, to anyone on the fence about Pelvic Floor Therapy…DO IT!!! As mentioned above, my erect penis was finally starting to falter…was really worried…well, not anymore. In the middle of my session, she was working my lower abdominal/groin area…I felt the blood flowing thru the lower half of my body again, I felt re-born. Then, suddenly out of nowhere bam, the FULL SIZE FULLY BOOKED plane was ready for takeoff. Little embarrassing, but she was great about it and said it’s to be expected. We’re activating those areas. Anyway, when I got home, I tested things. I couldn’t help myself. Shaft and head were completely hard again and one of the most pleasurable orgasms ever. I’m talking PRE-SAW PALMETTO!! I cannot stress this enough. The belief is because of our muscles falling apart, it’s cutting off blood flow and putting pressure on nerves. This can be opened up with internal (yes, you read that right, like a long prostate exam, once initial shock over, not that bad, don’t worry) and external therapy. I even got micro needling therapy in Perineum (this worked wonders). They hurt going in a little bit, then went numb, and so far since then, I feel like my old self down there. Scratch that, better than ever!! I’m seriously tempted to “test run” things another time, but won’t push my luck. I have enough Prolactin, thank you very much!
P.S. My flaccid size is constantly fluctuating now between Saw Palmetto small and “nearly” pre-fin. This is after 3 one hour sessions too (2 days a week). So, looking very good. Also, doing regular physical therapy/workouts with a personal trainer (3 days a week). Tough and very sore each day, but pushing as hard as I can (think I’m getting a little muscle back, again not too many sessions yet, but will keep you posted). Hired diet specialist as well. Testing all sorts of things. Will share everything I learn here. You guys have helped me save some bucks, so let me return the favor 
So, bottom line, don’t give up on sexual symptoms, give Pelvic Floor Therapy a try! I mean even my mood is better
So since I made the plane reference earlier, I’ll leave you with this: Tower, this is Ghost Rider requesting a flyby 
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Hey mate, Good stuff! stoked you are doing well! I suggest reading the “headache in the pelvis”. Just started reading myself, pretty informative.
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Thanks buddy! Just ordered the book, looking forward to it. Appreciate the tip 
Amazing article about one hell of a son. This should give us all hope: https://www.nytimes.com/2021/11/04/health/sharif-tabebordbar-gene-therapy.html?utm_source=pocket-newtab
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Hey man, how is the pelvic floor therapy going? I have severe shrinkage as well after saw palmetto and willing to give this another go with a professional.
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Please do and definitely with a professional. This is not something that you can do on your own. It’s working wonders sexually and with urination/defecation. Bear in mind, I’m not 100%, but definitely a significant improvement. I’m only 3 sessions in, so keep that in mind too.
While unrelated, I also want to mention that my gum loss appears to have stopped. All my gum loss was on the right side of the mouth. I’m curious if that has any significance. In terms of brushing my teeth, I’m actually celebrating my first week of no blood. All knock on wood.
Unfortunately, my ever growing skin suit continues unabated. Very similar to @Dknighten.
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More excellent news! Earlier this year, I introduced myself to Dr. Michael S. Irwig (who of course needs no introduction here!). He has been incredibly kind, helpful and responsive. In our most recent discussion, he shared with me his latest medical journal publication: “How routine pharmacovigilance failed to identify finasteride’s persistent sexual side effects.”
While technically not finished yet, this is where it will appear, so please keep an eye on the following link: https://pubmed.ncbi.nlm.nih.gov/34713622/
I neglected to mention, I expect results for my latest tests this week:
3 Alpha Androstenediol Glucuronide
DHT
Estradiol (E2) Sensitive
Prolactin
Vitamin D
I’m also scheduled to take these tests later today:
Growth Hormone (Serum)
IGF-1 (Insulin-like Growth Factor 1)
I will of course post these results as well. The second I have them.
My best to you all! Stay strong!
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@Fighter1 thanks for the updates buddy. The following articles are extremely relevant to our plight:
Basically, what the studies have concluded is that there is no issue with hormones, it lies with the neurosteroids in the brain as 5AR is also required to synthesize progesterone to dihydroprogesterone which is then converted to allopregnanolone
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Very interesting. Thanks for sharing and your support, pal!
Ok, I got two of my results in today. Oddly enough, they were the most recent tests. My assumption is, that since the others were bundled together, until the last one’s analysis is complete, I won’t be sent anything. I’m told 3-Alpha can take 14-16 days. So, betting it’s that one holding things up.
So, without further adieu, here are today’s numbers:
And here’s what I’m waiting on:
3 Alpha Androstenediol Glucuronide
DHT
Estradiol (E2) Sensitive
Prolactin
Vitamin D
Eager to hear your thoughts. Especially yours, @Cbrandel, I think you missed your calling
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Not much to be said really, you have a very healthy IGF-1 level which is generelly good (don’t know about it’s role in PFS but I’d say it’s positive).
As I posted recently in some other thread here, GH is secreted in a pulsative manner during sleep.
So it’s normal to have low levels while awake. But your IGF-1 tells us your GH secretion is healthy.
I’ll check in here again when more results are in 
.
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@Fighter1 the lab that is doing your testing - do they offer blood tests for the following:
Pregnenolone
Progesterone
Dihydro-progesterone
Tetrahydro-progesterone (aka Allopregnanolone)
Another major function of the 5 Alpha Reductase enzyme is to catalyze the conversion of progesterone to Dihydro-progesterone and if there is an imbalance it could explain why we feel so down. This may be worth investigating… I would do it but none of my local labs perform those tests
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