Thank you for elaborating a bit. I’ve looked into Clomiphene a bit more and see that it can raise SHBG levels. Given that I have pretty elevated SHBG levels as it is (53.1 with a reference ranged of 16.5 - 55.9 for my age group), I ultimately determined that this was not the route I wanted to take despite my doctor’s advice. I don’t think that there is anything wrong with my pituitary gland, so it’s probably not necessary to upregulate its activity.
Because I’ve decided not to use the Clomiphene, I figured I may as well run the Joekool protocol of 250 UI every other day for 3 days of the week rather than 1,000 UI every 3rd day. So while some of my HCG will go to waste (since it goes bad after 60 days of refrigeration) and I ultimately spent money on Clomiphene that I won’t use, I think it is the safer route so as not to increase my SHBG levels or desensitize my Leydig cells. I’ve been on countless websites and read parts of dozens of journals and found that high levels of HCG have been shown to desensitize leydig cell activity while low level therapies have actually shown to have the opposite effect! I should have flagged the specific studies that cite this earlier, but I can’t seem to find them now. Oh well.
So I started the protocol on 7/6/2021 and have since had two subcutaneous injections into my stomach with a 30 gauge insulin needle. Joekool said that he did subcutaneous injections but also mentioned that he injected it into his arm (???) so this is where I’m deviating from his method. It’s only been a few days but I feel night and day different and my libido is back to a place it hasn’t been since even well before the Finasteride usage. I almost cried tears of joy this morning when I woke up to morning wood and a very engorged member haha. I’ve had a couple occasions in the past couple days where I’ve been horny without the use of porn and I almost forgot what that felt like. I hope this dosage isn’t too high since it’s hitting me pretty quickly, but I’m going to try to reach out to Joekool to see what he weighs and possibly adjust my dosage accordingly.
I will keep this updated for the lurkers that are actually seeking help. For those of you that want to shit on everybody because misery loves company and you’re miserable people, go right ahead. I’m going to keep documenting this despite you.