Mifepristone worked

Therapeutic Efforts
#310

fair enough

#311

The difference between you and @Ronnie99 and @slick1 is that you are PFS from dutasteride when the two others who had lasting improvement are PAS.

Not only accutane and fin could have methylated different genes but from my understanding if you have AR issues regarding these substance in most cases PAS have downregulated ARs and PFS have upregulated ARs. So if what has been written about the impact on ARs of mifespristone is correct, (that it upregulated ARs) it is normal for PAS to improve with mifepristone. For PFS youi might upregulated them even further. It’s a bit like taking fin again, some feel some improvement for a bit and then feel worse.
This just my logic with the current info I have, I’m sure the mechanism are more complex.

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#312

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#313

The only way to figure it out is by seeing the results on another, remember PFS doesn’t make sense anyway, so there’s a fair chance that the cure also won’t make any sense :joy:

#314

Good question.

Please read the study below, and it shows what it done to bio markers in the brain loke you said. Its main mechanism of action is on the glucorticoid system and progesterone receptors.
including the fox O which is important in any person, and a few others, please have a good read.

#317

If anyone has a truly legitimate source, we’re all ears. This stuff is impossible to find, much less a reliable source.

#318

Hello everyone,

Please note this topic will now be closed per our latest update to the propeciahelp terms of service. If you wish to continue providing updates about how Mifepristone has affected your symptoms, please do so via the new reporting form in your member story: Changes to propeciahelp towards a more effective patient advocacy: Please read this important post about changes to our terms of service

Thanks,
PH team

#319