Low Basal NO/NOx Levels and Proposed Regimen

Mario, did you feel your testicles getting bigger, fuller?
The volume and consistency of your sperm changed?
What about your eye floaters?

Do you intend to stop all supplements one time, because if you do and feel fine that means you got cured.

If I were you I would add two things, first high dosage of asparagus, check finatruth he got excellent results. Also raw unpeeled carrots. These two things will improve your androgen receptors, liver function and remove estrogen and toxins, with your high NO your body will remove it even faster and better that would be good to see if you get really cured by this because your body will enter in a great recovery mode with the combination of your protocol with 5AR stimulation, AR sensitive and estrogen detox.

I’m saying it because chi got cured by doing it, he said is about gut and I agree but he was eating tons of asparagus and detoxing the body, he hĆ” da crash on milk thistle he said it was the too fast liver cleanse on it but if you check you’ll see that it is very estrogenic.

Just thought I’d throw this one in there but I plan on doing a colon and kidney cleanse followed by liver flushing, I think this takes fasting/detox to the next level.

Testicles : Yes they became fuller
Sperm Consistency : Was very thick (sperm test revealed mucus) but now is neither thick neither watery
Eye floaters : The same now as before

I want to try to stop supplementation and see what happens. Before that though i must check the state of my Thyroid and Free Testosterone ( i had the blood test today) so i will know very soon (3-4 days from now).

Sorry eye floaters is the same as before fin or before your protocol?

Testicles fuller is a huge sign of recovery I remember my recovery phases my balls always got bigger.

Now your sperm is normal? It’s another thing to pay attention.

I hope your protocol lead to a cure for everybody. Now do you think you feel totally pre fin? What about gynecomastia, muscle wastage?

Try to decrease everything slowly tappering off.

Your protocol is good because is not HRT so it can be a cure. What worries me is that NO is being increased artificially, so when you stop, less NO will be used to increase blood flow to the penis, I don’t know if NO can increase ball size, that’s a great sign, but also NO could’ve helped the body detox or enzyme production. I will try to follow your protocol with asparagus and carrots. Did you follow any specific diet like no carbs no sugar? Do you intend to post a recovery thread once you get cured?

Yes the situation of floaters did not change. Actually i had floaters before Finasteride intake. IMHO fuller testicles are a sign that they are functioning properly (i.e they produce testosterone)

I believe that impaired NO production is because of Oxidative Stress and particularly ROS (Reactive Oxygen Species) that run wild and uncontrolled. I must say again that it is very important to keep Glutamate excitotoxicity and Oxidative stress in check.

I got the first blood results :

Ferritin and Iron levels are normal now. (Ferritin was low because of high nitrate levels)

T3 : 1.0 (0.8-2.0 ng/ml)
FT3 4.4 (3.2 - 6.8 pmol/L)
TSH 4.5 (0.3 - 4.5 μIU/ml)
Creatinine 1.1 (0.7 - 1.2 mg/dl)

So it appears that my Thyroid is borderline normal but -in all fairness- i will have to recheck in 20 days to see whether TSH is outside of normal levels.OTOH results are very promising since i did not have any thyroid medication for the past 3 months.

Creatinine is on the highest normal levels which suggests that there might be something going on with my kidneys. I believe i know what happens : Increased ROS has affected my kidney function somehow. I hope that this is reversible.

I will post the summarized information, i am just so damn busy these days…

I started taking Folate 800mcg and Wheatgrass powder about 3 weeks ago. Brain fog has lifted, my brain feels constantly stimulated and awake, mental clarity has improved and I’m more talkative. Just wondering if anyone else has had similar effects from Folate? Otherwise it must be the Wheatgrass.

excelmale.com/showthread.php … xide-Stack

Nitric Oxide Stack

Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

Andyuk yes i have this reaction to folate and b12.
its very noticeable and ive reproduced it a few times so it must be that

Recently changed methylcbmn with adenosylcobalamin and i seem to react better to it.

I seem less anxious and more motivated, even only woth just a few days on it… Cant be just placebo… Sleep seems to normalize a bit but nothing miraculous.

Nitric oxide seems to improve more sleep i think…

Thanks Xptriado. I also become anxious from methylcbmn b12, so I don’t take it anymore. I’ll give adenosylcobalamin a try.
What folate doses are you taking? I’m doing 800mcg x 3 per day, although I notice the effects I mentioned from just 800mcg P/D.

@andyuk: i don’t think you need to take a lot of metafolin, i just take once, 800mg, as soon as i wake up.

@mariovitali: I’m ordering supplements and I lost track of some of your changes:
- why did you leave acetyl-l-carnitine? was it just because GPLC promotes NO? Do you have a study, I found studies talking about it increasing NO but in combination with exercise only.
- why did you stop taking Alpha Lipoic Acid?

The reason being I want to try 2 or 3 different protocols and to save money, I’m trying to see if I can reuse the supplements.

Right now I think methylation is helpful.
I’m goign to try this reduction of oxidative stress and ros.
And Uridine+DHA+Choline

Not at the same time of course.

This product has good reviews for increasing energy levels. It’s claimed to increase NOx due to it being made from beetroot. It’s called CocoCardio by Madre Labs.

Hi Guys,

Sorry for not being around lately but as discussed i work many hours a day lately.

The positive :

-Consistent quality of erections (still)
-Sleeping a good 7-8 hours every night
-Skin more oily
-Weather changes do not affect me anymore
-No incidences of Depression, Panic Attacks

The negative :

-Orgasm sensation down to 10% (because i had to use the ā€œBig Gunsā€. Read below what this means)
-I continue to need around 2 minutes of stimulation to get an erection.

So why this happens? I believe that throughout all of these years that i experienced tinnitus, damage has been made to neurons that are responsible for orgasm sensation. Also damage has been made to the ā€œcircuitā€ responsible for ā€œvisual stimulationā€ erections (there are two different ā€œcircuitsā€ that are used so that an erection is achieved). This is why old men need more stimulation to reach an erection.

I discussed about ā€œBig Gunsā€ which in my case is Taurine. I had to add Taurine so that i can control excitotoxicity. Unfortunately i experienced again Tinnitus last week (=excitotoxicity which kills neurons) which means that K2 was not enough. Note that this might be true just for me but for another person, Vitamin K2 alone might do just fine.

Why did i lost 80% of orgasm sensation? Because it is a logical outcome from years of excitotoxicity ā€œkillingā€ slowly neuronal cells :

Imagine -for simplicity- that you have 100 neurons that are responsible for transferring the signal for orgasm sensation. Over these years these neurons have been ā€œkilledā€ by excitotoxicity and now you have 20. If you take any substance that has an inhibitory effect to your nervous system (=GABA, Taurine, Glycine) then the neurons that have been left (only 20 by now) may not be eligible to propagate any signal at all. This means anejaculation (at worst you cannot have any orgasm at all) and loss of orgasm sensation (a better scenario)

This is why i am saying that stopping excitotoxicity should be our #1 priority.

My regimen is as follows :

Morning : Metafolin, Ashwagandha, Selenium, C, Taurine, Ubiquinol, D3, K2
11:00 AM : Pycnogenol
Lunch : Ubiquinol, GPLC
Around 10:00 PM : Taurine
2 times a week : Methylcobalamin and P5P
I eat my greens but a lot less than i used to. My ferritin levels are back to normal now (they were high because of high nitrate ingestion from Spinach/Rocket)

I switched to GPLC so i can have some glycine (inhibitory effect to nervous system) as well.

Taurine totals to 1 gram a day. After 1 gram of Taurine /day i have a complete lack of side effects for more than a week. This is the first time this happens but i will have to see that this continues.

There might be a way that my consistently high cholesterol will be much better because of Taurine. We will see. I also added Ashwagandha to help my thyroid a bit.

So : Make sure you stop excitotoxicity. Important neurons are destroyed every time you experience tinnitus or a crash (My theory)

Guys,

I think the whole PFS thing is over for me. After Taurine supplementation everything is gone. Every slight side effect, nothing is there.

My heart palpitations are gone. I tried a DHT inhibitor on purpose (Basil is one of them) and stopped it and i was expecting a crash (=Tinnitus). Nothing happened.

Now can i say that i am cured? That is an interesting question because the way that i see it and being one of the oldest sufferers in here, i think that my body suffered an awful lot of excitotoxicity and oxidative stress because of PFS all of these years. So the truth is that -quite possibly- PFS has caused me some irreversible damage. Had i known how to tame excitotoxicity earlier, may be i would not be in this situation. But you have the time to act. Let me repeat again : Number one priority is to stop excitotoxicity

You will recall that i have rather high Cholesterol levels and also increased blood coagulation. It seems that my cholesterol is now 230 without any change in my diet (at some point in the past had readings well over 290). My urine is not so dark now and i also have to push my finger for some time to stop the blood if i take a blood sample. Why? Taurine as it appears is a major constituent for bile synthesis and it helps in elimination of Cholesterol and controls blood coagulation. I believe that impaired Taurine production has also taken place over the years.

Actually i feel entirely normal apart from the fact that my orgasm sensation has been lost to 80%. However if i want to remedy that then this means that excitotoxicity will become a problem again and it will continue its deleterious effects on various parts of my body. Unfortunately, the methylation protocol alone was unable to stop excitotoxicity. Only GABA and Taurine could do that but i prefer Taurine because it is not so antagonistic with the NMDA receptors.

Some questions that remain unanswered :

-Will my body heal (neurons/receptors) ?
-How/Why Finasteride led us to this mess?

I will soon post the text that explains it all, a photo that i always wanted to post and my finalized regimen. I will continue to log in from time to time but i will need some time off from Propeciahelp.

In case i find something worthwhile i will let you Guys know.

Take care,

Mario

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1st day of beetroot juice (1carrot,1curcumin,1beetroot,60g spinach, 1apple,1broccoli, and some fiber from the disposals of the machine, drank half of it.):
Woke up middle of the night and as soon as i drifted off to sleep again i was gettibg jolt awaken. When i finallybfell asleep again, i woke up with noise but had already slept aroubd 7-8 hours so got up. I could have slept more if it wasnt that noise. Sleep was not continuous.
Nornally i sleep 5 and then lie awake for 2hours and then its an incognito if i am able or not to sleep 2hours more.
Woke up with a morning erection which hasnt happened withouth benzos in…months

Overally i slept well and better than before.

Today will be the second day…

Mario, did you stop supporting NO directly?

Not needed anymore xptriado, i just some greens as i normally would. It appears that :

Oxidative Stress => Low endothelial NO Production

NO downregulation could be a mechanism to protect us from further oxidative damage or something else is going on. As soon as Oxidative stress is taken care of, everything falls into place.

Mario, I’m restarting the protocol. Should I start with pycnogenol twice daily for oxidative stress or replace pycnogenol supplement with Glisodin and Curcumin or just add these two supplements to the regimen? Also do you have any recommended time lengths on how long to take pycnogenol?

xptriado how many times a week are you taking B12 Adenosylcobalamin?

Thanks guys

I’ve got some questions and some considerations.

1 - Mario did you stop all the supplements? I mean, are you now med/supp free and feeling 100% normal?
2 - Did you have loose stools? With this NO protocol you did, did you notice any difference like normal stool and bowel movement? This is really important because it would mean that your liver was/is better.

Now please I will copy what I wrote in another thread and will try to write more things too.

Please guys try to search anything on this line Estrogen Dominance, Digestion, Liver improvement.

I think we have estrogen dominance and I will tell you why.
You took propecia, I ate too much soy, drank too much green tea to lose weight (it is 5AR blocker). If you search for people who have the same issues we’re facing you will see they took, propecia or accutane, SSRI, Birth Control Pills, Gall bladder removed.

Finatruth said he is recovered from asparagus (it stimulates the 5AR, body balance, improve digestion) but I don’t know what will happen if he stops. When we stimulate the body like this, get a great digestion I think it’s the best time to do all we can do to detox the excess estrogen.

Justquitdut got better by increasing 5AR expression, you said you’re not cured but symptom free, I think the problem of taking too much hormones that when you start to stop the use you will get another imbalance and will be harder to be free of it.

Letsconvenience got cured by removing estrogen/copper, he used ox bile, antiestrogen food and suplements.

Chi got cured or better by eating asparagus (he ate so much that I think all the results he got wasn’t about diet or anything else) he also got a crash by taking milk thistle that is highly estrogenic.

IHP got cured by improving digestion with enzymes, food, herbs. He said he would feel worse on Diflucan (it increase E and lower adrenals)

Elb got cured by doing the progesterone treatment in his own way. He said everytime he would drink or smoke marijuana he would get a crash.

Beekay got 95% cured by doing progesterone cream while decrease estrogen at the same time (I think he just couldn’t reach 100% because he took clomid that block estrogen and then increase it right after).

Light at the end got totally cured and I think he also did this elimination of estrogen by Maca, progesterone, food, exercise.

Cdnuts got cured by decreasing estrogen too.

Marioitali got symptom free by increasing NO production it does all the things a normal hormone profile would do like digestion, wood, sensitivity, etc. I think would be a great time to expell estrogen.

All the people who got better or got cured has something in common, detoxing estrogen and improving digestion. Mario did the same thing but in other way increasing NO. He said all symptoms cleared and I know that when we get hormone balanced our body produce naturally NO. You can see when normal people try TRT or cycle steroids their veins get bigger, get more muscle mass. When our body produce NO the brain receive oxygen again and we get cleared from brain fog.

Another 2 questions to Mario.

1 - You said you still have eye floaters, but your vision got better overall? Like no more blury?
2 - Do you think your hormones got balanced now? I mean no more estrogen dominance symptoms like no libido, no morning wood, ED, increased body fat, bloating, awakening tired, etc. If not if you get better why don’t you try to go to the progesterone cream protocol or any other way to reduce the rest of estrogen that is inside your body like the eye floaters that still need to be repaired? I’m saying that because when I first used the progesterone cream and it worked I felt great 70% normal, just a little bit more energy and libido I would be feeling normal, but now it is not working anymore I’m still trying to figure a way to the cream be effective again.

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Asparagus and a high fat zero carb diet!! My results have been jaw dropping from this diet. I am no longer bloated. I couldn’t even sleep last night because I was hard as a rock.

Everything seems to work for you though. :stuck_out_tongue: