I want to document that I woke up feeling maybe twice as good as I’ve ever felt since Invega.
No dyslexia like yesterday. I think I dodged a bullet by quitting the inositol after only 3 days instead of 4 weeks like I originally intended.
So I just performed that most scientific of all experiments (n=1 not 2 unfortunately) twice in succession and it was very anti-climactic. The relevant muscles barely worked at all. It seemed like a lot of output with almost nothing outputted, and now I have blue balls except deeper than my actual balls.
Also, my dick ended the experiment strongly identifying as a rubber garden hose, whereas just before it strongly identified as a 160 degree angle. I believe it is confused. On the bright side, my mood is still good enough to joke about the sorry state of my own penis. And being mentally functional is more important than otherwise. I never had the opportunity to know exactly what I’ve been missing out on the past 9 years, anyway.
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Keep us updated on your insoitol use! It caused a crash in me and caused dyslexia for me as well
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My bloodwork results have a lot of stuff, but here is what I figured is most relevant. I was told everything is normal except vitamin D, although I don’t see “Vitamin D” in the results.
| Creatinine | 1.0 mg/dL |
| Cholesterol | 124.0 mg/dL |
| Triglycerides | 52.0 mg/dL |
| HDL Cholesterol | 49.3 mg/dL |
| LDL | 64.0 calculated |
| TSH3 | 3.94 mIU/mL |
| Free T3 | 4.0 pg/mL |
| Free T4 | 1.15 ng/dL |
| FOLW | >24.00 ng/mL |
| Cortisol | 21.0 ug/dL |
| SHBG | 23.2 |
| Testosterone | 440.6 ng/dL |
| Free Testosterone % | 66.3 calculated |
| Free PSA | 0.27 ng/mL |
| PSA | 0.78 ng/mL |
| DHEA-S | 610.5 ug/dL |
| hGH2 | 1.118 ng/mL |
| LH | 6.48 mIU/mL |
| Estradiol | 20.8 pg/mL |
| Progesterone | 1.86 ng/mL |
| Prolactin | 18.70 ng/mL |
I replied in a private message but for the record, the dyslexia didn’t last more than 30 minutes and hasn’t come back.
Your TSH is in borderline hypothyroid territory.
DHEA-S is high.
Estradiol borderline low.
Progesterone is also way high.
Prolactin is slightly out of top range.
I had to convert everything because USA refuse to use international metrics for some reason. So I might have made some miscalculations but I don’t think so.
They didn’t give you any reference ranges?
Edit: Cortisol also slightly above range.
I found the Vitamin D entry. Here’s everything marked “high” or “low”:
| Name | Result | Flag |
|---|---|---|
| Vitamin D 25-Hydroxy | 26.8 ng/mL | Low |
| hGH2 | 1.118 ng/mL | High |
| Prolactin | 18.70 ng/mL | High |
Off-topic, but I want to note that the curvature and other deformations I described can be “fixed” manually at about 80%, but at >95% they correct themselves.
Also I know I swore off herbs earlier but I figured the dyslexia had to be from either the inositol or French maritime pine bark extract, and I wanted to recreate the previous couple of short-lived successes, particularly of the anorgasmia, so I again tried less than a capsule full of each of the following:
- Tribulus
- Tongkat Ali
- Muira Puama
- HGW
- Fenugreek
- Maca
- Cordyceps
Not a success. After a few hours I took the same thing again, and all I got was deep despair.
I also came across a Reddit post where nipple itching was described as one step away form gyno, and that scared me a lot because I was thinking that morning that my nipples might have looked slightly bigger, so I think I won’t touch any of these, especially the fenugreek, ever again. For real this time.
In the interests of transparency, I may have randomly subtracted or added 1 to the least significant digit of some of the results. I feel more comfortable posting my results that way and I don’t think it makes a relevant difference.
| Name | Result | Units | Reference Range |
|---|---|---|---|
| TSH3 | 3.94 | mIU/mL | 0.34 - 5.6 |
| DHEA-S | 610.5 | ug/dL | 85 - 690 |
| Estradiol | 20.8 | pg/mL | none |
| Progesterone | 1.86 | ng/mL | 0.14 - 2.06 |
| Prolactin | 18.70 | ng/mL | 2.64 - 13.13 |
| Cortisol | 21.0 | ug/dL | none |
Thanks for the pointers, I will do some more research on these specifically. In the meantime if anyone has any suggestions on how to correct anything that needs correcting, preferablly “naturally”, that would be great.
I hope the aforementioned herbs didn’t affect my results too much.
According to my Google searches, it seems that:
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A high TSH3 would be 4 (mine: 3.94)
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High DHEA-S would be 640 (mine: 610.5)
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High estradiol would be 50 (mine: 20.8)
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High progesterone would be 0.9 (mine: 1.86)
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High prolactin would be 20 (mine: 18.70).
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High cortisol would be 20 (mine: 21.0)
Just as I reference, the ranges I used are from Swedens best university hospital where I got my blood tested (Karolinska).
TSH <4.2
DHEA-S <450
Estradiol <40
Progesterone <0.16
Prolactin <15
Cortisol (7-10 AM fasted) <20
It can vary depending on what testing method they use though, so generally speaking it’s best to use the reference ranges they provide (if they’re a legit lab).
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Is that a typo? My progesterone is 1.86, almost 12x higher.
I don’t think so, Karolinska has the refence range for males to <0.47 nmol/L.
Using this converter that equals to 0.1478 ng/mL.
But to be fair my local lab has the ref <2 nmol/L which equals 0.63 ng/mL.
I don’t know which to believe then, because on my paper it says:
Progesterone Results Interpretation:
Males: 0.14 - 2.06
Which implies my 1.86 is on the high side, but still okay.
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Yeah it’s kind of weird.
This is taken from Healthline.
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Progesterone is found in much lower levels in men and isn’t typically tested unless adrenal gland dysfunction is suspected. Normal levels are less than 0.20 ng/mL.
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Keep in mind that results can vary between laboratories. If you’re unsure about your test results, contact your healthcare provider.
If I were you I’d probably get re-tested with a different lab just to validate.
I want to document a few more things:
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This symptom still hasn’t come back, although I still have extremely mild face acne and rare nipple itching from the herbs I took so it’s possible I’m just riding the positive effects and the cringe will come back.
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Also, while taking the herbs my body odor would occasionally return. I didn’t even realize it was gone until the first time it came back.
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I have never “crashed”; e.g. had anything resembling a long-lasting reversion to a former, worse state from anything I ever did or ate.
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I’ve seen multiple hypothyroid people on Reddit cite inability to look people in the eye as one of their symptoms. I will have to investigate the possibility that hypothyroid medication may help, especially this particular symptom (if it ever returns).
6 days now without the “social cringe” that made it uncomfortable to look people in the eye. I can safely say I am cured from that now, after ~9.5 years.
Yesterday for a hot minute I had zero perceivable symptoms, and could interact, talk, walk, and laugh normally. I could feel everything fully, including how beautiful the day was and how nice the wind was blowing. I told myself, “I am in paradise.” 
I turned on some music and was stunned by how amazing it felt. I thought, this is absolute euphoria. But, my definition of euphoria has suffered severely since Invega. I can remember that before, listening to music was about the most enjoyable thing in the world to me, and I could completely forget how screwed I was from Lexapro if I laid down and closed my eyes while listening to it. This “euphoria” is something I used to experience every day.
Then POIS in the form of physical and mental fatigue suddenly hit me from an-O-mia that morning. I was snapped back to the reality that I am still far from the finish line.
Today was similar.
I think this is my new normal.
I am planning on TRT …
The improvement seems to have been permanent. Although, along with it something bizarre happened. Something else completely loss its characteristic odor, which has never happened before ever. Fortunately I was able to quash my fears of having become infertile with some very cheap equipment.
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It’s been years since those panic attacks, but in general I do feel worse in the morning and better around 2 PM, with mood declining afterwards. Looking at my labs again, which were taken at 8:45 AM after awakening at 7 AM:
| Measured | Reference Range (AM) | |
|---|---|---|
| Cortisol | 21.0 | 6.7 — 22.6 |
So, my AM cortisol is near the upper limit of “normal”?
Documentating and speculating some more miscellaneous things:
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In agreement with an observation made by someone else at the naked scientists forum, POIS is significantly less bad if focus had been on her pleasure. This even works with porn, and presumably pure imagination. Why? Does it increase a chemical (estrogen?) that somehow counteracts whatever is causing POIS?
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Post-Lexapro panic attacks began a handful of seconds after waking up and lasted several hours. I believe it was 3 hours. What hormone is released suddenly within a few seconds of waking up and then wanes over a few hours?
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The white spots vary in intensity but are always in the same place, even when the surrounding skin is purple. What causes skin to appear white when the surrounding skin is purple? Increased capillary blood flow? Why? Some sort of receptors in those specific, sub-millimeter regions are permanently (over a year) altered? What type of receptor?