The Baylor research will (hopefully) enlighten us further, but the best guess is that the research will show that we have silenced AR genes in certain tissues.
Its entirely possible that this is a downstream effect and in that scenario it opens a can of worms. Its entirely possible that this is more neursteroid related and that opens a seperate can of worms.
But based on the evidence we have so far, the most rational theory is summarized in sentence 1.
With that, further research will surely need to be conducted. I am 100% on board with helping to fund this research. Its a must.
BUT, the pace is too slow for us living in the now. We need a sub-group of us to pinpoint a lab or multiple labs in China that is willing to use CRISPR to edit our AR gene(s).
There are a number of barriers to this: (1) I’ve read a study that showed there is small chance that the change in the genome could ultimately go back to being modified (2) $$$$ (I am going to try to find out the price of such an experiment) (3) Finding legit labs willing to do this (4) China has cracked down in the past year on “black-market medicine” (5) Finding a few PFSers willing to be the subject.
I am going to begin contacting labs and scientists and seeing where I can get with this.
FWIW, I had set up an experiment with a lab in southern California around 4 years ago that would have used penile tissue to verify if we had silenced AR. We would have known the results 3 years ago, but unfortunately I was talked out of it by someone telling me to “just wait for the Baylor study its almost here”.
We need to continue to support the Foundation’s endeavors and future research while also taking part of this ball game into our own hands.
If anyone is interested in being a subject, please PM or post in this thread.
If anyone has reached out to any scientists or labs around the world to assess their capabilities and interest in this experiment please, let PM me or post in this thread.
I understand that this thread is probably better suited for SolvePFS.com, but that site has been merged with this one.