but I read curcumin is anti-androgen as well.
I’m sorry, but can you tell me what HC and NE stand for? Also, what is i PGE2? Are you referring to taking tylenol on a daily basis if DO have ED instead of NO ED? I will look up information on curcumin, but I am curious as to why you say to take tylenol.
Thank you very much martinM for your reply. I have to thank you also for all your dedication on this thread. That is very interesting what you say about Vitamin D. I will look up information on that as well. I have actually noticed notable performance increases when I began drinking 1,000IU of Vitamin D a day from the Emergen-C drinks. I do have about 800 IU of Vitamin D a day from the multi vitamins that I take, but I have not noticed any performance changes with that amount. I will check out those websites. Thank you for those links.
i read that stuff also but others say it doesn’t effect their hair whatsoever so if it influences dht a lot i don’t know for sure, but i am on testosterone as well 125 mg a week so there will be no deficiency of androgens there
i think i can handle a curcumin tab or two a day
JN,
thanks for the info. All of the research that I did prior to taking HC, was that 20-25mg should be the max dosage for a day. I never went higher than 20mg per day. Who knows, maybe I needed more of it.
I know what you mean regarding remembering to the take the doses, it’s really a pain in the ass. It’s not like you just take it once day. You need to take it 4 times a day at very specific times and I forget as well.
I never took just T3. I took Armour and only felt some effect from it in the beginning stages of taking it. Now that I see you are still having such good results with T3, I may try to locate a doctor that knows more about thyroid & adrenals.
He takes t4 as well I believe. 40mg of it.
JN- I believe 27mgs was the max recommended on STTM.com, but ive seen plenty of people who need more.
.
HC is hydrocortisone. Useful if your adrenals are underproducing at all times of the day, but if overproduction in the AM followed by underproduction in the afternoon is the issue, phosphatidylserine is a better option (have tried both, and have the saliva and serum cortisol tests to prove it).
Thank you for the information.
On another note: JN said this advice I advise anyone here to take their body temperatures at 4 different times throughout the day, get a full thyroid screen including Reverse T3 and a full adrenal screen via a saliva test.
Is this the same type of thing that Dr. Crisler does? I’m very confused about which treatment path I should attempt to take. Dr. Crisler says that he does some sort of HPTA restructure. Is this the same thing you are referring to? Right now I am going to get the recommend blood tests and talk to my doctor about what you have said JN. But not sure where to take it from there.
I see Dr. Crisler is known for his TRT type treatments so I am confused who I should be seeing. I have been browsing a lot over at stopthethyroidmadness and the real thyroid help forum. If I want to follow JN’s advice, should I be following advice from the thyroid related sites or does the HPTA restructuring thing work as well?
I am very sorry about my lack of information on the subject, I have been reading and trying to educate myself for about 8 hours last night and most of today to try to learn more on this subject. Thank you all for your input as it has proven so valuable to me any many others.
Hey chaps,
Just a couple of points after reading recent posts:
-
I don’t take Vit D supplements. I don’t believe in it. Good evidence suggests we probably aren’t universally low in Vit D. Also, evidence shows it increases ionised calcium, which gets deposited in arteries (bad) instead of bones. Hard calcified arteries are bad. Don’t take calcium supplements either.
-
Thanks for the advice re, HC. I’m currently taking 35mg per day, probably too much. However, and this is important, I’m introducing Florinef (fludrocortisone) which is probably being suppressed by T3.
To be succint, adrenal cortex makes 2 important hormones which I believe are suppressed by the T3 I am taking.
1st one is a corticosteroid (cortisol basically, so I take hydrocortisone)
2nd one is mineralocorticoid (aldosterone)
I know for a fact that my cortisol has been suppressed by T3. I feel better on hydrocortisone.
But I need to replace my mineralocorticoid activity, so I am taking fludrocortisone, starting off at 0.025mg per evening, (which is a quarter of a 0.1mg tablet, increasing my dose by a quater of a tablet every week). I take it with a teaspoon of salt and I’m eating 5 or 6 dried apricots per day. (salt to help the fludrocortisone boost my blood volume, and apricots as it’s an excellent source of potassium).
I have bought a blood pressure cuff to ensure BP doesn’t go high.
Currently I feel a bit dizzy on standing up, and also I have frequent urination, which I believe is related to low mineralocorticoid activity.
I should really have checked my renin and aldosterone levels prior to having started florinef, but I haven’t got round to it, and I’ve had the florinef sitting in my fridge for a few months now.
Chaps, I’m not trying to scare anyone with science here, or be too crackpot, but I’m confident I need mineralocorticoid activity. See thyroid websites.
I reckon this could be the final piece of the jigsaw.
It is well stated in STTM that I should be able to reduce my dose of HC.
Could we move the conversation forward to discussing fludrocortisone?
Anyway, I’m feeling damn good. Surfing tomorrow, going to a nice restaurant, playing tennis…wow, life is good. Take care
JN
I started some threads about aldosterone a while back.
I thought many times of going on TRT but my past experience with Agel plus your long struggle…
I am neither as knowlegdeable as you are nor I have resources to these all. I wish you could come with a final solution sooner.
sps
do you think mineralocorticoid activity is important because of its ability to lessen inflammation?
JN do you have any study about VitD? I think vit D gave me new life. In Dec 2009 I was in very bad condition thinking daily I woud die. What about TUMs? My bones are very weak if I don’t take calcium supps then how should I increase bone density? If you google you will see pastuerized milk is not good too. Instead of giving calcium to bones , it draws out calcium from bones.
sps
"Hc saved my life and fixed my ED
before that, never, no go, no show, nothing, not even a bare function
theories:
our bodies are in an inflamed state, and has too much stress hormone norepinephrine
HC lowers NE sufficiently, adds to our depleted cortisol production line, and is anti inflammatory
take tylenol or curcumin if you have no ED and see if it improves your time… anti inflammatory andi PGE2
to everyone, thank me in a couple years"
I agree. I believe cortisone has cured me. I posted in the member section how taking Prednisone has recovered my body.
After Propecia i ve become severely alergic to a lot of foods, and i found it out the worst way, eating. So in the past year and a half i ended up taking Prednisone to treat my inflamed lungs about 15 times. So basically every month, i took it for 5 days, 40 mgs a day. Then after a month or so i would eat something and get inflamed lungs again. 5 more days of Pred. Everytime i took it, i felt more sensitivity sexually, and closer to normal mentally. It was as if my body was lacking the cortisone to heal itself. Now i follow a special diet, very strictly, and i feel very normal, with no need to take cortisone or any medication. And sexually, i have rock hard erections, great orgasms and love sex again.
It is as if Prednisone has restarted my adrenals.
But i think it is very risky to take HC on a daily basis. It will eventually stop your adrenals. And you will need to be on it for life. It is not easy to mimic your adrenals. From my experience, if you want to try cortisone, you can try it the way allergies are treated: no longer than 7 days (my doctor never prescribed it to me for more than 5 days). It is very safe and effective if done that way.
-
The body of scientific evidence strongly disagrees with you-- you mentioned surfing, australia, you may well have enough. But it’s a simple thing to get tested-- if you’re low, take D supps, if you’re not, don’t. It’s important to have enough, and the only way you will know is by testing.
-
I’m not sure about your wording here-- I don’t think T3 suppresses your adrenal cortex, but rather lowers your cortisol by the increased demand from the higher levels of T3. It could be a problem if your adrenals aren’t making enough to keep up with the demand, but this may not necessarily be a problem of the ac, but could also be your pituitary or hypothalamus. It’s an important distinction, I think.
-
Yes, you definitely should have.
-
Doesn’t seem a good reason to start taking it. I’ve also got a bottle of Florinef thats been in the fridge for 7 or 8 months, but without ensuring that I need it, I would never start taking it just because it’s there!?!
-
You do, but you may not need to supplement with fludro to get it. What evidence do you have that you need it? Sure, lots of people with thyroid/adrenal problems need it, but lots don’t. And taking it when you don’t need it is a bad idea. Sorry to sound like a broken record, but test test test.
-
Truly glad to hear it.
Are you planning on getting a 24 hour urinary cortisol test to make sure the HC dose you’re taking is appropriate?
definitely
HC lessens inflammation as corticosteroids do
i have a 90-95% reduction in hayfever symptoms from this shit as well, awesome
over on the musclechatroom board everything starts with adrenals, and chilln is pimpin transdermal preg as a precursor to all adrenal hormones for maximum effect, but haven’t tried that yet
vitamin d is major important. even in sunny countries you’re still probably low… don’t think it is bad for you… for me it took my test levels from 300 to 550 after 6 weeks of 10.000 iu daily and it took me to almost top of the range
it needs to be balanced with other vitamins as well such as vitamin a, since that can become lower
i really recommend getting a good multi vitamin in high dose, energy revitalization system is pretty good according to reviews on iherb
also for ppl with adrenal issues who don’t want to go to HC straight there are adrenal cortex glandulars… another one i read good reviews on iherb is adrenal stress end by enzymatic therapy
fludrocortisone haven’t tried that but would def be willing, but at the moment im cruising along fine like JN is
only issue still is wood, which improves for me on high dose arimidex… i am considering switching/testing aromasin as this is stronger and is a suicide inhibitor meaning it makes aromatase inactive
arimi is a competetive inhibitor and it doesn’t do the job good enough for me… after my test shot for 5 days i will feel really sweaty in the armpits and if i don’t take arimi on shot day i end up soaking the bed cloth with sweat
i need to try some more regular higher dosing of arimi since it is way cheaper than aromasin, but could be harmful on the lipids which i need to measure if i go on that higher dose
JN good to hear you’re doing great, and good luck trialling fludrocortisone, let us know how it goes… many ppl on the thyroid boards are helped with it, so let us know how it goes
please indeed be careful of high blood pressure since you may have it naturally, but is amplified by TRT… HC also increases blood pressure (good for those with low cortisol and low blood pressure) but may be too much for you… how much is it now? be careful when adding fludrocortisone
You need to clear out liver, so it can deal with e2 effectively.
You need to keep on HC and maybe increase it and thyroid hormones so that e2 is lowered.
After being on HC for a week, I feel like my inflammation has increased. I feel it more in my eyes and when I pee, but I have no prostate problems… This only happens ever so often… so weird…
JN, you should also get your sodium/potassium level checked out if youre going to take Flurinef. I remmeber someone on here, I think his login was Letsconvince and he had a hair test done and his sodium/potassium ratio was reallly screwed up…
Hey guys.
-
Thanks for the advice, discussion and points thrown forward. Thanks growlingmadscientist for your points especially; you make good points.
-
I took florinef for 2 days. It gave me a headache and did little else. 2 hours before starting, I noted I did not have a postural drop in blood pressure. I don’t think I need it. I don’t have true adrenal fatigue (prior to T3 I had high cortisol, DHEA, prgesterone). I have, as growlingmadscientist stated, suppression of cortisol due to high T3.
-
Over the last 2 days, I have ceased T3 therapy. Yes, slowly reduced over 48 hours. When I wake up tomorrow morning, I will not take a dose of T3. May I say I feel better already. I have got 2 spontaneous erections of 100% quality, I got out of bed due to the call of nature and to test myself, and I annoyed my girlfriend earlier with serial demands for sex.
The problem with taking hydrocortisone (for the rest of one’s days) is that a man doesn’t have a spontaneous on-demand rise in cortisol required for immediate sex or for extreme exercise. I am struggling to keep pace with a high demand tennis match and my tolerance for exercise is somehow less on hydrocortisone.
I have got rid of all my reverse T3 (and have proved it on bloodtests). Now I will try to come off. I will continue to take hydrocortisone for a few more weeks, but gradually wean myself off it.
So far, so good.
Take care,
JN