Hey guys,
Pax here. Haven’t been on in a little while, but I saw this and wanted to chime in a little bit.
First off, as far as one can be without having consumed the stuff, I’m pretty familiar with Ibogaine. I even have a small (but hopefully growing) Ibogaine fund for, well, potentially abating or ameliorating our mutual plight. Among new age shamans, herbalists, and those who subscribe to such trains of thought, Ibogaine is known as a powerful healer, allegedly able to, yes, repair DNA.
Whoa, whoa, whoa. Hold on there. DNA repair? Seriously?
[Size=4](you’ve got to be sh.tting me)[/size]
Let’s put the hocus-pocus on the backburner for a moment. In a nutshell, here’s what I do know about Ibogaine.
Tabernanthe iboga is a plant indigenous to the jungles of Gabon, in Africa, where local pygmy tribes such as the Bwiti consume its root bark as part of a rite of passage into adulthood. Some tribes only offer this to men. Some tribes whose belief systems have been influenced by missionaries allow women to undergo this rite as well. Blah blah blah. It lasts three days, and you pass through a diamond-shaped (or something) made of sticks tied together that symbolizes passing through the vagina (i.e. rebirth). During this entire process, the individual communicates with his/her spirit ancestors or the ancestors of the Bwiti people or both, whatever.
And so basically, you trip balls for a while, and are reborn. Sounds pretty cool.
Well, somebody with a heroin addiction tried Ibogaine, and it ended up curing him. The lengthening of nerves is encouraged by NGF, nerve growth factor. The sprouting of new neurons is influenced by the body’s production of BDNF, Brain-Derived Neurotrophic Factor. These are proteins, and there are many such like them that do different things. VEGF (Vascular Endothelial Growth Factor) enhances the growth of blood vessels. Growth factors are most often proteins that: grow stuff in your body!
Well, Ibogaine influences the production of a special growth factor called GDNF, or Glial Cell Line-Derived Neurotrophic Factor. Phew, that was a mouthful! Anyway, when you use drugs, your brain “turns to mush.” The more drugs you use and the longer you use them, the mushier your brain becomes. GDNF is like brain glue. I’m sure it has other functions, but one of the principal activities of GDNF is preventing the apoptosis of dopaminergic neurons in the midbrain. When you take Ibogaine, your body upregulates GDNF drastically, enhancing dopaminergic activity and sensitivity, creating a positive feedback loop where GDNF is bolstered not just for the duration of the drug’s psychological effects, but for an entire month.
There’s another substance that affects GDNF in the world of traditional medicine. Some of you have tried it, and with mixed results, some of you haven’t. It’s Royal Jelly, a special variety of “honey” that turns a regular ol’ bee into a queen. http://en.wikipedia.org/wiki/Royal_jelly. Touted for it’s anti-aging properties, RJ has a substantial, although comparatively mild, effect on the expression of GDNF. Practically, pre-dose RJ and go out binge drinking, retain some sort of clarity and wake up the next day feeling as fresh as clean linen. Yes folks, it works. I’ve read stories and tried it myself. Last New Years, I was consuming several mind-altering substances when a friend needed a ride, and I drove him around for a while. Then, after taking many, many rips of “tobacco” out of a waterpipe, I was still completely coherent.
So, they have clinics in Canada and Mexico where any heroin addict (with enough money, of course) can walk in, dose, and walk out. Clean. You have more than the power not to use again, you don’t even want to.
You can check out trip reports on erowid.org http://www.erowid.org/experiences/subs/exp_Ibogaine.shtml. 12-step and similar conventional substance abuse treatment centers are notorious for their appallingly low success rates.
Back to the hocus-pocus: so they say it repairs your DNA. Correct me if I’m wrong, but we’ve got some problems with our genetic code. Sounds too good to be true, though. If you read enough accounts of others’ Ibogaine experiences, you’ll read about people who’ve seen (Ibogaine trips are characterized by realistic, dreamlike visuals) their DNA fix itself, double-helix and all. Some people report the ability to decide to change, and then like the flick of a light switch, they do. Given the lack of empirical evidence and intellectual similarity to quackery, this phenomenon sounds optimally dubious, but the sheer volume of anecdotal evidence is compelling, at least.
Oh yeah, Ibogaine purportedly decalcifies and activates the pineal gland. Much other stuff too.
I forget what else to say, I may come back and update this post, but let me just say that IMO, Ibogaine has a better chance of giving us a normal life again than any other botanical out there.
PS theres also Sapo/Kambo, which is much different, and you don’t trip, but anyway, here, read about it:
http://www.erowid.org/culture/characters/gorman_peter/gorman_peter_article2.shtml
PSS goes without saying, feel free to pm me