Guillain-Barré syndrome seen in users of Isotretinoin

You might have just seen GBS mentioned in my most recent Coronavirus post.
Its worth making a note of this.

Guillain-Barré syndrome seen in users of isotretinoin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC437146/

1 Like

I might follow up on this when I get a chance.

Ganglionic acetylcholine receptor autoantibodies in patients with Guillain-Barré syndrome.

https://www.ncbi.nlm.nih.gov/pubmed/27235349
Patients with GBS may have circulating antibodies against gAChR, which may contribute to the autonomic dysfunction associated with this disease.

Ganglionic Acetylcholine Receptor Autoantibody, a marker of neurological autoimmunity

It looks like they pulled the first SSRI from the market strictly because of its tendency to cause GBS.

According to this document a second generation SSRI was not ruled out as a causative factor for inducing GBS in a small number of cases.

1 Like