Forskolin reportedly promotes weight loss and increases AR... Has anyone tried it?

Forskolin is one piece of the puzzle as it increases adenylate cyclase - cAMP - PKA. The main issue is why is adenylate cyclase inhibitied?

The biggest impact on my recovery to date has been chamomile tea, Ashwagandha and Forskolin. I stopped Chamomile tea for 3 days and I began having flushed skin, itchy body and nipples, ear canals aching, tinnitus, sleep problems, anxious, couldn’t think straight and heart irregularities and the feeling of increased estrogen, which i havent had since I started chamomile tea over 8 months ago…These are some of the main symptoms when I was at my worst. I read up a bit more about Chamomile tea as I already new about Apigenin and it’s benefits with star protein and it’s inhibitory effects on HDAC and methyltransferase.

The results shed light on what I feel is a major piece to PFS. We’re having autoimmune to increased histamin, which increases histamine and causes a brutal cycle. All these histamine symptoms that I was trying to overcome for over a year, comes down to increases estrogen levels. I had three chamomile tea bags in hot water last night and within 30min I was feeling back to normal. Turns out apigenin inhibits estrogen through inhibition of aromatase.

Apigenin also may have direct links to multiple pathways in regard to our condition. When I look back at my notes from the beginning of the year, I’ve written Chamomile is the key and instantly made me feel better.

Highly recommend if you have histamine, gyno issues.

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I’m not saying Apigenin is the key to our recovery, but it may lead to key links to the root cause.

Apigenin : a proposed research target for ME/CFS, PFS, GWIS and more

algogenomics.blogspot.com/2019/0

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Nice.
I am sure AR problems are one of pfs causes.
Do you think forskolin is safer than tribulus?
I will try tribulus based on April protocol,but it may affect me nothing,so I want to have many choices.
I also drink coffee every day and take carnitine every other week,but I don’t find outstanding improvement.

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Also I am interested in this.
an approach different from tribulus or forskolin.

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add.

and this

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@Trump_1776 @CursedLemon how is it going?

I am putting in an order of Forskolin now. I think I am going to run cycles of that and tribulus, apart from each other, so two weeks on one then two weeks on the other.

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I returned it to Amazon, didn’t get anything out of it.
Moving on :stuck_out_tongue:

Did you take it on an empty stomach, as soon as you woke up?

Nope

I read it needs to be taken like that to be effective. I am going to get some in and take that approach, will feed back.

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No significant changes, I’ve also been taking chamomile tea frequently along side it and my brain fog has been slightly better since - but that fluctuates anyway.

Are you taking it on an empty stomach as soon as you get up?

Yes.

So what’s the difference between tribulus and forskolin?
Not just AR increasing?or strength?

Tribulus is a testosterone booster, while Forskolin is purported to promote hormonal balance (as well as weight loss, which it is primarily marketed for).

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hmm
Then considering reports,testosterone booster is more effective than hormon balance promoter?
Tribulus affects stronger in terms of producing AR than forskolin?

There is no definitive answer, as everything is so unknown, but I am an adherent to the idea that our hormonal balance needs to be restored, which Forskolin seems more apt for, whereas Tribulus is more useful for pure T boosting (and I have certainly noticed improved penile sensitivity and ejaculation sensation while cycling it).

Given that both supps seem to be best cycled, I am intending to cycle them each two weeks on interchangeably, so from tomorrow for two weeks, I will cycle tribulus, and then during my two weeks off of tribulus I will cycle Forskolin, and then repeat.

‘Hormonal balance’ was thrown out the window 10+ years ago if you read through the forums far back enough, if this was a simple matter of too little test or too much estrogen for example then we wouldn’t still be discussing it. Almost all mentions of Forskolin on this forum are usually mentioned with the intention of increasing cAMP which it is well known for - see the thread I linked in the fourth post of this thread for the reasoning behind that.

That being said, I doubled my dosage of Forsk’ yesterday and have noticed some mental improvement lasting into today. It’s difficult to specifically describe it but I certainly feel some brain fog relief, improved mental clarity and less depressed than usual. It’s only been a day and half however so I’ll post an update in a week or so at the same dosage to see if things continue this way.

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Forskolin affect dopaminergic system also.

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