Forskolin is one piece of the puzzle as it increases adenylate cyclase - cAMP - PKA. The main issue is why is adenylate cyclase inhibitied?
The biggest impact on my recovery to date has been chamomile tea, Ashwagandha and Forskolin. I stopped Chamomile tea for 3 days and I began having flushed skin, itchy body and nipples, ear canals aching, tinnitus, sleep problems, anxious, couldn’t think straight and heart irregularities and the feeling of increased estrogen, which i havent had since I started chamomile tea over 8 months ago…These are some of the main symptoms when I was at my worst. I read up a bit more about Chamomile tea as I already new about Apigenin and it’s benefits with star protein and it’s inhibitory effects on HDAC and methyltransferase.
The results shed light on what I feel is a major piece to PFS. We’re having autoimmune to increased histamin, which increases histamine and causes a brutal cycle. All these histamine symptoms that I was trying to overcome for over a year, comes down to increases estrogen levels. I had three chamomile tea bags in hot water last night and within 30min I was feeling back to normal. Turns out apigenin inhibits estrogen through inhibition of aromatase.
Apigenin also may have direct links to multiple pathways in regard to our condition. When I look back at my notes from the beginning of the year, I’ve written Chamomile is the key and instantly made me feel better.
Highly recommend if you have histamine, gyno issues.
