Finasteride and Immune Depression

General Discussion
#1

A greeting to all those who have had problems with finasteride.
I would like to draw attention to a fact that will surely affect many of you, and naturally from the state in which I am: it is now scientifically established that finasteride acts suppressively on lymphocytes, especially on CD8, thus creating a decrease Of total lymphocytes and consequently also of leukocytes, often creating chronic leukopenia and lymphocytopenia.
This immune system creates a situation where viruses, bacteria and other pathogenic organisms have more strength to infect our organism, in my case it has happened with the virus ebv.
I’m doing cortisone therapies to lower the inflammation and the mild autoimmunity that has arisen with the defeat to the immune system and stimulate the bone marrow to produce more white blood cells that according to the reasoning of the immunologist specialist from which they should be followed then should then To the body to increase the number of lymphocytes.
Did any of you have an immune problem similar to mine? If so, how is he or she treated you or did you care? Did you hear the opinion of immunologists or infectologists about it?

Thank you, good luck at all.

#2

Scientifically established? Could you post a link if there is a research released on this please, as it’s the first time I hear of it.

#3

ncbi.nlm.nih.gov/pubmed/27253400

This is one, but I have noticed that physicians (especially immunologists and infectologists) share the fact that finasteride has a detrimental effect on the immune system.

#4

Hello Cedric,

Do you feel improvement with cortisone?

#5

Hi Blasé, then, cortisone therapy, according to my immunologist should primarily increase the number of white blood cells, and then redistribute the amount of lymphocytes, now low, and secondly decrease the inflammatory state but this was not sought after. A mere cortisone effect. What I can say is that at high dosage I was very good at 100% but with low dosage I was not at well. Now I’ve finished taking it, and in a two-week period i’m going to do the blood tests. Anyway I’m starting to feel good again. Within a few days I will do the exams and see if the effectiveness is also reported by the values.
How are you at the immunological level?

and Vanquish… how are you?

#6

I haven’t had any immune system problems post-fin, at least none that I’ve noticed. Other than that, I gave up looking for a cure, after 10 years of PFS I don’t think there will be a cure in my lifetime or at least when I’m still young. I might get a penile implant after summer, which won’t help with sides such as muscle wastage etc., but at least I’d be able to have somewhat normal sex.

#7

Hi Cedric,
How do you feel after experimenting with cortisone?

#8

Please take a look at the book “The Medical Medium” -very interesting insights into EBV and how EBV can play a roll in “Mystery Illness” which you’re on this forum, I would think you agree a lot about this illness is very much a Mystery.

#9

Hi Blasé;
Then, I used the medium/low dosage of flantadin first and gave me side effects like malaise and weakness. So the immunologist prescribed me Medrol at medium/low dosage: the first doses at average dosage were 100%, when instead I decreased dosage, i feel yet paresthesia, numbness, weakness, strong feeling of fever;
However, I have almost completed the expected timing of therapy. I did the examinations required by the immunologist, on weekends I will have the reports. Currently enough well.
How are you? Do you have immune problems?
Hello!

#10

Yes I have inflammation.
When you say 100% you mean it brings yoy back to 100%?

#11

Yes, in my case.
Now, i’m to 80% of condition. Maybe i do another cycle of cortisone. I’m waiting an answer from immunologist for whether or not to continue therapy.

#12

Cedric,

Are you still feeling pretty good ?

So if I’m following correctly you started with high dose cortisone which gave you great results, lowered your cortisone dose which made you feel bad and than switched to medrol at a high dose and felt good followed by decreasing the medrol and felt bad?

How long have you been on the cortisone and
Medrol for in total? have your lymphocytes increased on your latest labs?

Could you please post your labs for us so we can see exactly what to get tested for?

Justquitdut tried cortisone i believe and got improvements and if I remember correctly he contributed cortisone to being important in his recovery

#13

Hi, what dosage of Medrol is optimal for you? How long do you use it?

#14

Hi, sorry if I answer you now, but I was fine and did not write a bit about the forum.
So as I told you I did a last cycle (which I’m finishing) of cortisone (corton acetate, the same molecule as our body) for a month at a relatively low dosage. All of the symptoms before were no longer seen because the cause was only one: lowering potassium in the blood and symptoms like paresthesia, exhaustion, tachycardia, etc. This cycle made with potassium integration was totally without side effects. I feel at 90%, the lymphocyte count before this cycle was “good” according to the immunologist, in October / November I will do it, but I think it is very good for how I feel.
The white blood cells were on the verge of limitation, but I think they have now recovered.

#15

When I take the exams in October / November I will post them.
I took Medrol x 3 weeks, same time for Flantadin. Corton acetate 1 month ca.
The first was too bland, the second I did not understand the cause of the symptoms (we understood it later, when I had suspended it), with the acetate corton zero problems.

#16

Please dont stop to do that.

What do you think are the test we should measure to detect something is wrong with the inmune system?

Thank you

Finasteride definetly damage inmune system somehow, please keep us informed! I also had a recovery using prednisone and doing some protocols that lower inmune activity, I havent had a fever since pfs.

#17

Sorry for interrupting but I need to ask. All, I really mean all my PFS blood results show high lymphocytes and leukocytes, not low. What would that mean?

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#18

Hello have you have information about this issue? Im ectremly interestedd in test regarding inmune system while in pfs, could you direct me to some information about that?

#19

High leukozytes means you have an inflammation. It is probably your gut which is inflamed (leaky gut for example).

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