I also have somewhat anhedonia and emotional blunting. What’s interesting is that I can use magnesium (lactate seems best) to modulate this somehow. If I’m without magnesium and I start taking it, it brings temporary recovery to some degree; more emotions, libido and penis sensitivity. Then the body adapts and I go back to my PFS state, which today consists primarily of emotional and libido issues together with the hellish penis sensitivity issue.
If I then quit magnesium when I’m on it, another temporary recovery-like state appears. This goes on for some days but then I go back to the state I’m usually in.
I use Prescript Assist (PA) and it actually helps quite a bit with the penis sensitivity issue (!). So there is something happening with signals/receptors that is related to the gut and that helps me here.
Today I take PA and magnesium. I occasionally take some Citrulline Malate since it helps with blood flow and exercise gains.
However, if I take too much Citrulline, Glutamine or even touch BCAA I can get rather hellish anhedonia. I took 1-2 scoops of BCAA the other day and I was sitting in my sofa wondering what the point with being alive was. Pretty scary, mildly put. Citrulline also has a 6 week washout (atleast the corresponding NO) so I can actually feel it for those weeks. I feel somewhat vulnerable when I go down to baseline without it.
I will try tyrosine and levodopa but it doesn’t seem these are any silver bullets from what I’ve read on here, so I’m rather pessimistic.
If you decide to try magnesium (or if you’re on it) please be aware that magnesium oxide seems to lower stomach acid over time. I read this on the web, but I don’t remember where. This can completely wreak havoc for us PFS sufferers who probably have a vulnerable gut in the first place. It did to me; I developed malabsorption, anxiety, pelvic pain symptoms and sleep problems from it and I’m still taking loads of HCL pills trying to repair my digestion. I can take 10 and more of them without getting any acid reflux. When I started HCL my sleep problems subsided, as did the anxiety and many of the “stress response -> pelvic pain” problems I experienced. However, I must say that I would love to feel a bit anxious since I’m starting to forget how it feels.
I would advice anyone having PFS to try HCL to see if stomach acid is low.