Oh also modafinil is a wakeful agent. It’s not even close to a real stimulant. It will do nothing for libido
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Forskolin also increases dopamine receptors as well as their sensitivity. This could be one explanation to why I’m seeing positive improvements after starting supplementation with Forskolin.
Forskolin-induced up-regulation and functional supersensitivity of dopamine D2long receptors expressed by Ltk- cells.
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That’s very interesting. In this video at the 2:11 mark it talks about the different variations of dopamine receptors (long and short). I have the C/C allele meaning I do not have “long receptors” or very little amount.
I should mention I took forskolin and baking soda yesterday with coffee (increase camp) and I had sex and masturbated three times after that. I was thinking what the hell is wrong with me, i have never done that even as a teenager. This is just a one off so I will try and replicate this.
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I see supplements ranging from 250 to 2100 mg
I took 500mg forskolin, 2 teaspoons of baking soda, 2 coffees.
I also took 300mg b6, 2.4g tyrosine, 1 teaspoon of mucuna, 30k iu vitamin A, 1.5g tribulis, 9mg boron, 10g creatine and 13g of BHB
Doing keto diet, only eating once a day and this day I lifted weights for 2 hours.
Forskolin and baking soda are the newest things I added to my supplements.
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Do you put ghee and MCT oil in your coffee?
I’ve been doing this every day and my mood and energy are improved.
It’s basically keto/ bulletproof coffee.
Only MCT, I intend to try ghee one day. Scared of the taste lol
the taste is not bad… It’s not “good”, but it’s not bad lol
You say you’re symptom free right now. Was is the forskolin?
Why baking soda?
I think it was the forskolin, keto and mixed cardio and weights on the same day. Those seem to be the things that make me symptom free. In terms of the mentals the best improvement came from hot jacuzzi to cold shower treatments. Best clarity after those.
Was reading how it increases receptor sensitivity. I was doing it for a bit and felt ok. Not bad.
Biggest improvement was not feeling lactic acid when I did weights
How long have you been doing keto? I might give it a go. I’ve also been doing mixed weights and cardio. I try to lift 3x per week in the morning and do cardio every morning I don’t lift as well as every evening
I did keto for like 3 weeks. I keep intending to get back on but it’s been one of those months. I still feel good but felt best on keto.
Stick to a keto diet free of artificial sweeteners and free of polyunsaturated fats. Macros maybe 40% protein 50% fat and 10% carb. Time your carbs pre workout.
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Did keto make you irritable? I did it for 3 weeks and felt like an asshole. I think it’s because your gut uses carbs to make serotonin.
I also think dopamine is a very important part of the puzzle. The lack of dopamine (or problem with the receptors) explains why most PFS people still have erections during the night (testosterone) but not during the day (dopamine). I’m also convinced it’s the main reason for the loss of libido. Dopamine releasing stimulants are the only way (temporarily) bringing back my libido.
The supplement uridine should be interesting, as it promotes the growth of new dopamine receptors in the brain. I have tried it but haven’t used it long enough to draw any conclusions.
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From doing some research it says uridine upregulates dopamine receptors, is our androgen receptors are likely upregulated than maybe dopamine is too? Wouldn’t this just make our symptoms worse to use uridine? @ithought
I don’t have the medical knowledge to answer that question but this wouldn’t make sense to me as we would be immune to chemicals or actions that release dopamine in the same way we are to androgens. I don’t have high expectations though, as some people on the forum have used it with initial improvements but no long term success.