This enzyme converts Dopamine to Norepinephrine.
Please correct me if I’m wrong but I was surprised not to see this posted on/discussed in any searches.
As I’ve posted elsewhere I think that Norepinephrine can cause wakefulness/stress and obviously low Dopamine can cause sexual issues. As someone whose main symptoms are lack of sleep/libido it’s very relevant.
Less so for people with brain fog as I believe low Norepinephrine causes this; I don’t have that symptom and think mine is too high.
This would tie into poor reactions I’ve had to Carnitine and Tyrosine which both increase that hormone (directly or via Dopamine). Apparently same for Rhodiola, Maca and Gingseng though I’ve not tried them. Also explains why Zinc helps with sleep for me (see below).
Still looking at this but wanted to get a discussion going if anyone is interested. I am very interested in things that can tie together the reactions I’ve had to supplements.
‘Dopamine beta-hydroxylase (DBH) is a copper-dependent enzyme. Zinc can influence its activity by competing with the binding of copper. In a context of zinc insufficiency (which is rather common), the conversion of dopamine to norepinephrine might be excessive, because there’s inadequate zinc available to dampen the enzymes activity.’