benefits from dexa reinforce prostate theory
NF-kappaB Is Involved in Prostate Inflammation
Possible role of nuclear factor-kappaB in intraprostatic inflammation
NF-kappaB influences the activity of many genes involved in inflammation. To judge whether NF-kappaB is involved in prostate inflammation, the researchers injected a proinflammatory cytokine into mice with a gene that helped illuminate where NF-kappaB was in the body. They showed high levels of NF-kappaB activity in the intestine, spleen, lungs, prostate, thymus, and skin. Mononuclear cells, a type of white blood cell involved in inflammation, accumulated in the small blood vessels and in the prostate. Giving the mice the anti-inflammatory and immunosuppressive drug dexamethasone reduced the migration of the mononuclear cells and the severity of inflammation in the prostate.