I started having terrible insomnia and worsening of PFS symptoms after taking methylcobalamin and SAMe. Started searching through all of the PFS/PAS/PSSD forums looking for a similar experience and found that @douglasmich and @Konflict both posted on solvePFS that something similar happened around the same time they took methylcobalamin (methylated B-12).
@adrian, There was a PAS patient I was in contact with years ago that said he had a severe worsening of sexual symptoms and after taking huge doses of D3. He also said the D3 triggered development of gynecomastia. I can’t remember the amount he took, but he was genuinely terrified by what it did to him.