I have read medical literature that stated high doses of testosterone has been beneficial to males with AR insensitivity, sometimes even correcting their problem. I remember that one member here, I think it was Dustin, had some benefits with very high doses of test.
I assume that high doses, super elevated levels, of testostorone could have some adverse affects on a males health.
But here is my thoughts on the matter. Maybe in a male with normal test levels, super high doses could affect his health.
But for us with pfs, itās the belief that are receptors are not working correctly so does having a high level of test in our blood mean anything?
If are receptors are not reconizing the test, why would it have any negative consequences? The main goal would be to try and squeeze as
much testostorone into our faulty receptors, overload it.
We would have to take arimidex to keep estrogen down. If this has helped men with AR why canāt it help us? Iām not a doctor and by no means thinks anybody should try this without one, or even if this is viable. I just wanted to write this and get varying opinions on this. Hopefully by those that have more of a sceintific base then I do.
I just know what Iāve read.
well we dont necessarily know if the AR is the issue, yet, but i think one of those papers mentioned something like R81 which is a very very strong testosterone analogue to correct AR issues if they are infact the problem.
Excuse my dumbness Golf, but what is a testosterone analogue?
I think he means this very closely(chemically) resembles the natural testosterone.
During my last trip to Dr. S that is exactly what he suggested. He suggested I take high doses of test cyp. He said he wanted me to inject high doses of Test cyp to wake up the receptors. He said Dr. Crisler is getting good results with this type of treatment. I have not tried it yet. I am still trying the synthroid first from another endo doctor I am seeing. If that does not work I will try the test cyp with a little HCG, which he also suggested to do along with the high doses of test cyp.
His protocol was to use .3 ml to start and work my way up to .5 ml injection. Taking a shot in the abdomen or anterior thigh two times a week. The needle to be used is a 25 gauge 5/8th needle. Additionally he also said to take 250 units of hcg two times a week to keep the bodies natural testosterone producing. The test cyp bottle says 200mg/ml oil injection sq. He did want blood test every two to three weeks to keep the estradiol checked. He said this treatement would definately get me feeling very good probably the best since taking propecia, with the hopes of waking up the receptors to keep me feeling good even after I would stop.
This may be some of the literature you are referring to:
Dr. Jacobs has reported success with pushing his patientsā free T levels to the upper envelope of what is considered to be a physiological dose. I have not yet tried this. When I doubled my dose from 1 to 2 tubes of Testim daily my T levels dropped below the levels I was at post-finasteride but pre-Testim while my DHT levels skyrocketed and my hairloss accelerated. I may be willing to try supraphysiological doses of T but will hold off on it for now.
please let us know your results if you go down this road
Its not uncommon on this thread to feel worse (at least sexually) after boosting testosterone levels. So i dont see it helping everyone.
Also, even the positive effects of high doses of T/DHT fade away after a while, this was the case with Dustin and whalen72 (viewtopic.php?f=5&t=3509&start=20).
Nobody undertaken this teatment with a PFS doc has ever mentioned anything about it on the forum, so it would be good to get some more feedback.
I would like to try testosterone injections, cause my situation is unbearable. But my testosterone levels are still in range (in the lowest part), so i canāt find a doctor in spain who accepts trying this option.
We have record here of Shippen trying this with two guys: boston332 and wtfhasthisshitdone, neither of whom appeared to get any benefit at all. I hope Crisler isnāt being economical with the truth.
what about this guy? - jeffO
Luckfax is right. That is exactly the protocol I tried last with Shippen. From the size of the needle you are referring to he took his shots Sub- q also. Iāve heard second hand that is the way Shippen takes his own T shots. I was up to over double or more the ānormalā dosage of Depo T and the only response from the T shots were a flushing to the face at the time of injection and of course extreme testicular shrinkage. Really donāt know where to go from here. Maybe thyroid hormone, hcg, arimidex and TRT together? I never really tried another ārestartā protocol after TRT so maybe another round of clomid/hcg? I really am not wild about the idea of going back onto TRT to be honest considering I had zero benefit before. Not to mention some offices are nearly impossible to work with when it comes to getting scripts for controlled substances.
What do you think about him? That its Dr Crisler or another PFS doc in disguise? (viewtopic.php?f=29&t=5600) Hes taking a high dose but its not āsuper highā.
It could just be some other random endo - I think JeffO lives in CA right?
Jacobs has also said he has some people who respond to very high test.
I also know someone personally who took fin for 7 years and now is on trt, he says most days are āpretty goodā
I would like to see if the AR is actually affected before trying this myself however.
Either this guy was contacted by a PFS doc or mew to take part in the magazine article. If not from mew it must be a PFS doc. If no other pfs patient was contacted by a PFS doc that makes the story suspectā¦ or am I just paranoid?
I would be interested to know where this information is from, is it information directly from Dr Jacobs? As far as I can tell this has not been the experience of people on this forum.
See this post from āppsā on Tue Jul 13, 2010 3:17 pm:
viewtopic.php?f=33&t=3757&start=20
I would be doing this right now if testosterone didnt make me feel worse.
The guy that got his T level up to 4000 I would love to know his estradiol level for that same time. It might well have soared out of control. I wish things were looked at in more specific detail.
I know ive had surges in libido from aromasin and arimidex which have been seemingly from the T increase as oppposed to E2 decrease.
word
I think Xhorndog can shed some light here. He was on Tinjection+clomid+Arimidex and stayed for long.